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P61084

- DEOC2_STAAM

UniProt

P61084 - DEOC2_STAAM

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Protein

Deoxyribose-phosphate aldolase 2

Gene
deoC2, SAV2137
Organism
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity.UniRule annotation

Catalytic activityi

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei151 – 1511Schiff-base intermediate with acetaldehyde By similarity
Active sitei180 – 1801 By similarity

GO - Molecular functioni

  1. deoxyribose-phosphate aldolase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbohydrate catabolic process Source: UniProtKB-HAMAP
  2. deoxyribonucleotide catabolic process Source: InterPro
  3. deoxyribose phosphate catabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Ligandi

Schiff base

Enzyme and pathway databases

BioCyciSAUR158878:GJJ5-2196-MONOMER.
UniPathwayiUPA00002; UER00468.

Names & Taxonomyi

Protein namesi
Recommended name:
Deoxyribose-phosphate aldolase 2 (EC:4.1.2.4)
Short name:
DERA 2
Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase 2
Phosphodeoxyriboaldolase 2
Short name:
Deoxyriboaldolase 2
Gene namesi
Name:deoC2
Ordered Locus Names:SAV2137
OrganismiStaphylococcus aureus (strain Mu50 / ATCC 700699)
Taxonomic identifieri158878 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000002481: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 220220Deoxyribose-phosphate aldolase 2UniRule annotationPRO_0000057258Add
BLAST

Proteomic databases

PRIDEiP61084.

2D gel databases

World-2DPAGE0002:P61084.

Interactioni

Protein-protein interaction databases

STRINGi158878.SAV2137.

Structurei

3D structure databases

ProteinModelPortaliP61084.
SMRiP61084. Positions 7-215.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0274.
HOGENOMiHOG000241645.
KOiK01619.
OMAiSGGIHSR.
OrthoDBiEOG6QZMW5.
PhylomeDBiP61084.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00114. DeoC_type1.
InterProiIPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/FbaB/lacD_aldolase.
IPR028581. DeoC_typeI.
[Graphical view]
PANTHERiPTHR10889. PTHR10889. 1 hit.
PfamiPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFiPIRSF001357. DeoC. 1 hit.
TIGRFAMsiTIGR00126. deoC. 1 hit.

Sequencei

Sequence statusi: Complete.

P61084-1 [UniParc]FASTAAdd to Basket

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MNSAKLIDHT LLKPESTRTQ IDQIIDEAKA YHFKSVCVNP THVKYAAERL    50
ADSEVLVCTV IGFPLGASTT ATKAFETEDA IQNGADEIDM VINIGALKDG 100
RFDDVQQDIE AVVKAAKGHT VKVIIETVLL DHDEIVKASE LTKVAGADFV 150
KTSTGFAGGG ATAEDVKLMK DTVGADVEVK ASGGVRNLED FNKMVEAGAT 200
RIGASAGVQI MQGLEADSDY 220
Length:220
Mass (Da):23,341
Last modified:April 26, 2004 - v1
Checksum:i4C658CF15A637077
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000017 Genomic DNA. Translation: BAB58299.1.
RefSeqiNP_372661.1. NC_002758.2.

Genome annotation databases

EnsemblBacteriaiBAB58299; BAB58299; SAV2137.
GeneIDi1122153.
KEGGisav:SAV2137.
PATRICi19565152. VBIStaAur52173_2211.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000017 Genomic DNA. Translation: BAB58299.1 .
RefSeqi NP_372661.1. NC_002758.2.

3D structure databases

ProteinModelPortali P61084.
SMRi P61084. Positions 7-215.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 158878.SAV2137.

2D gel databases

World-2DPAGE 0002:P61084.

Proteomic databases

PRIDEi P61084.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB58299 ; BAB58299 ; SAV2137 .
GeneIDi 1122153.
KEGGi sav:SAV2137.
PATRICi 19565152. VBIStaAur52173_2211.

Phylogenomic databases

eggNOGi COG0274.
HOGENOMi HOG000241645.
KOi K01619.
OMAi SGGIHSR.
OrthoDBi EOG6QZMW5.
PhylomeDBi P61084.

Enzyme and pathway databases

UniPathwayi UPA00002 ; UER00468 .
BioCyci SAUR158878:GJJ5-2196-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00114. DeoC_type1.
InterProi IPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/FbaB/lacD_aldolase.
IPR028581. DeoC_typeI.
[Graphical view ]
PANTHERi PTHR10889. PTHR10889. 1 hit.
Pfami PF01791. DeoC. 1 hit.
[Graphical view ]
PIRSFi PIRSF001357. DeoC. 1 hit.
TIGRFAMsi TIGR00126. deoC. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Mu50 / ATCC 700699.

Entry informationi

Entry nameiDEOC2_STAAM
AccessioniPrimary (citable) accession number: P61084
Secondary accession number(s): Q99SC2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: April 26, 2004
Last modified: July 9, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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