Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P61084 (DEOC2_STAAM) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Deoxyribose-phosphate aldolase 2

Short name=DERA 2
EC=4.1.2.4
Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase 2
Phosphodeoxyriboaldolase 2
Short name=Deoxyriboaldolase 2
Gene names
Name:deoC2
Ordered Locus Names:SAV2137
OrganismStaphylococcus aureus (strain Mu50 / ATCC 700699) [Complete proteome] [HAMAP]
Taxonomic identifier158878 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length220 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity. HAMAP-Rule MF_00114

Catalytic activity

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP-Rule MF_00114

Pathway

Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP-Rule MF_00114

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00114.

Sequence similarities

Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandSchiff base
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbohydrate catabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

deoxyribonucleotide catabolic process

Inferred from electronic annotation. Source: InterPro

deoxyribose phosphate catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiondeoxyribose-phosphate aldolase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 220220Deoxyribose-phosphate aldolase 2 HAMAP-Rule MF_00114
PRO_0000057258

Sites

Active site1511Schiff-base intermediate with acetaldehyde By similarity
Active site1801 By similarity

Sequences

Sequence LengthMass (Da)Tools
P61084 [UniParc].

Last modified April 26, 2004. Version 1.
Checksum: 4C658CF15A637077

FASTA22023,341
        10         20         30         40         50         60 
MNSAKLIDHT LLKPESTRTQ IDQIIDEAKA YHFKSVCVNP THVKYAAERL ADSEVLVCTV 

        70         80         90        100        110        120 
IGFPLGASTT ATKAFETEDA IQNGADEIDM VINIGALKDG RFDDVQQDIE AVVKAAKGHT 

       130        140        150        160        170        180 
VKVIIETVLL DHDEIVKASE LTKVAGADFV KTSTGFAGGG ATAEDVKLMK DTVGADVEVK 

       190        200        210        220 
ASGGVRNLED FNKMVEAGAT RIGASAGVQI MQGLEADSDY 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000017 Genomic DNA. Translation: BAB58299.1.
RefSeqNP_372661.1. NC_002758.2.

3D structure databases

ProteinModelPortalP61084.
SMRP61084. Positions 7-215.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING158878.SAV2137.

2D gel databases

World-2DPAGE0002:P61084.

Proteomic databases

PRIDEP61084.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB58299; BAB58299; SAV2137.
GeneID1122153.
KEGGsav:SAV2137.
PATRIC19565152. VBIStaAur52173_2211.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0274.
HOGENOMHOG000241645.
KOK01619.
OMASGGIHSR.
OrthoDBEOG6QZMW5.
PhylomeDBP61084.

Enzyme and pathway databases

BioCycSAUR158878:GJJ5-2196-MONOMER.
UniPathwayUPA00002; UER00468.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00114. DeoC_type1.
InterProIPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/FbaB/lacD_aldolase.
IPR028581. DeoC_typeI.
[Graphical view]
PANTHERPTHR10889. PTHR10889. 1 hit.
PfamPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFPIRSF001357. DeoC. 1 hit.
TIGRFAMsTIGR00126. deoC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDEOC2_STAAM
AccessionPrimary (citable) accession number: P61084
Secondary accession number(s): Q99SC2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: April 26, 2004
Last modified: July 9, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways