P61004 (PATR_CORDI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative phenylalanine aminotransferase
EC=2.6.1.-

Gene names

Name:	pat
Ordered Locus Names:	DIP0178

Organism

Corynebacterium diphtheriae [Complete proteome] [HAMAP]

Taxonomic identifier

1717 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	344 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May catalyze the transamination reaction in phenylalanine biosynthesis By similarity. HAMAP MF_01513
Cofactor	Pyridoxal phosphate By similarity. HAMAP MF_01513
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

Ontologies

Keywords
Ligand	Pyridoxal phosphate
Molecular function	Aminotransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 344	344	Putative phenylalanine aminotransferase HAMAP MF_01513		PRO_0000153510
Amino acid modifications
	Modified residue	213	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	P61004 [UniParc]. Last modified April 26, 2004. Version 1. Checksum: 97057C59E9FEB49D	FASTA	344	37,000
	10 20 30 40 50 60 MIRKDLSQIP TYVPGKRNDH ALKLSSNEVT HRPLPSAAQA MAEAAAGANR YPDMGVTELR 70 80 90 100 110 120 GALSEHLGVP AEQIAVGCGS SALCQQLVQI TCTPGDEVVF PWRSFEAYPI FVQVVGATPV 130 140 150 160 170 180 AVPLTSDGFN DLDAMAAAIT PKTKLVFVCN PNNPSGTVVR REAFLEFMAK VPADVVVALD 190 200 210 220 230 240 EAYTEYVRDE DTIFATEILS EFPNLVGLRT FSKAFGLAGV RVGYAFGPHE LIDALNKVAL 250 260 270 280 290 300 PFGVNAVGQA GALASLNNLD ELMEHTEEVV AVRDRVADHI GAAHSQANFV WIPAESRSET 310 320 330 340 PFEIAEKLAA HDVLVRAFPE GVRITVTNEE ESDRLLAAWD ASFA

References

[1]

"The complete genome sequence and analysis of Corynebacterium diphtheriae NCTC13129." Cerdeno-Tarraga A.-M., Efstratiou A., Dover L.G., Holden M.T.G., Pallen M.J., Bentley S.D., Besra G.S., Churcher C.M., James K.D., De Zoysa A., Chillingworth T., Cronin A., Dowd L., Feltwell T., Hamlin N., Holroyd S., Jagels K., Moule S. , Quail M.A., Rabbinowitsch E., Rutherford K.M., Thomson N.R., Unwin L., Whitehead S., Barrell B.G., Parkhill J. Nucleic Acids Res. 31:6516-6523(2003) [PubMed: 14602910] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700971 / NCTC 13129 / Biotype gravis.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX248354 Genomic DNA. Translation: CAE48682.1.
RefSeq	NP_938570.1. NC_002935.2.
3D structure databases
ProteinModelPortal	P61004.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2648854.
GenomeReviews	Gene locus DIP0178 in contig BX248353_GR.
KEGG	cdi:DIP0178.
NMPDR	fig|257309.1.peg.161.
PATRIC	21481507. VBICorDip47633_0166.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG646350.
OMA	NNTKIVW.
PhylomeDB	P61004.
ProtClustDB	PRK03321.
Enzyme and pathway databases
BioCyc	CDIP257309:DIP0178-MONOMER.
Family and domain databases
HAMAP	MF_01513. Phe_aminotrans_2. [Tree]
InterPro	IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR024892. AroT. IPR005861. HisP_aminotrans. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00817.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01141. HisC. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PATR_CORDI

Accession

Primary (citable) accession number: P61004

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 26, 2004
Last sequence update:	April 26, 2004
Last modified:	January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program