Reviewed, UniProtKB/Swiss-Prot P60989 (PIP_PANTR)

Names and origin

Protein names

Recommended name:
    Prolactin-inducible protein homolog
Alternative name(s):
    Prolactin-induced protein

Gene names

Name:

PIP

Organism

Pan troglodytes (Chimpanzee)

Taxonomic identifier

9598 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Pan

Protein attributes

Sequence length	146 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Subunit structure	Monomer. Interacts with AZGP1 By similarity.
Subcellular location	SecretedBy similarity.
Sequence similarities	Belongs to the PIP family.

Ontologies

Keywords
Cellular component	Secreted
Domain	Signal
PTM	Glycoprotein Pyrrolidone carboxylic acid
Gene Ontology (GO)
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 28	28	By similarity
	Chain	29 – 146	118	Prolactin-inducible protein homolog		PRO_0000024291
Amino acid modifications
	Modified residue	29	1	Pyrrolidone carboxylic acid By similarity
	Glycosylation	105	1	N-linked (GlcNAc...) Potential
	Disulfide bond	65 ↔ 91		By similarity
	Disulfide bond	89 ↔ 123		By similarity

Sequences

	Sequence		Length	Mass (Da)
	P60989-1 [UniParc]. Last modified April 26, 2004. Version 1. Checksum: 792863048C9E8BF0	FASTA	146	16,575
	10 20 30 40 50 60 MRLFQLLFRA SPATLLLVLC LQLGANKAQD NTRKIIIHNF DIPKSVRPND EVTAVLAVQT 70 80 90 100 110 120 ELKECMVVKT YLISSIPLQG AFNYKYTACL CDDNPKTFYW DFYTNRTVQI AAVVDVIQEL 130 140 GICPDDAAVI PIKNNRFYTT EILKVE

References

[1]	"Divergent evolution of the prolactin-inducible protein gene and related genes in the mouse genome." Osawa M., Horiuchi H., Tian W., Kaneko M. Gene 325:179-186(2004) [PubMed: 14697523] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Origin and evolution of gene for prolactin-induced protein." Kitano T., Tian W., Umetsu K., Yuasa I., Yamazaki K., Saitou N., Osawa M. Gene 383:64-70(2006) [PubMed: 16949771] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Isolate T028 and Isolate T030.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB098482 Genomic DNA. Translation: BAD04930.1. AB251899 Genomic DNA. Translation: BAF35619.1. AB251900 Genomic DNA. Translation: BAF35620.1.
RefSeq	NP_001009170.1.
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSPTRG00000019801. Pan troglodytes. [Contig view]
GeneID	494144.
KEGG	ptr:494144.
Phylogenomic databases
HOVERGEN	P60989.
Family and domain databases
InterPro	IPR007990. SV_autoAg. [Graphical view]
PANTHER	PTHR15096. SV_autoAg. 1 hit.
Pfam	PF05326. SVA. 1 hit. [Graphical view]
PIRSF	PIRSF002572. PIP-GCDFP-15. 1 hit.
ProDom	PD021604. SV_autoAg. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

PIP_PANTR

Accession

Primary (citable) accession number: P60989
Secondary accession number(s): A0A883

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 26, 2004
Last sequence update:	April 26, 2004
Last modified:	November 25, 2008
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)