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Protein

Putative transport protein YidE

Gene

yidE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:EG11536-MONOMER.
ECOL316407:JW3662-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative transport protein YidEUniRule annotation
Gene namesi
Name:yidEUniRule annotation
Synonyms:yibE
Ordered Locus Names:b3685, JW3662
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11536. yidE.

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei4 – 24HelicalUniRule annotationAdd BLAST21
Transmembranei28 – 48HelicalUniRule annotationAdd BLAST21
Transmembranei65 – 85HelicalUniRule annotationAdd BLAST21
Transmembranei95 – 115HelicalUniRule annotationAdd BLAST21
Transmembranei158 – 178HelicalUniRule annotationAdd BLAST21
Transmembranei371 – 391HelicalUniRule annotationAdd BLAST21
Transmembranei393 – 413HelicalUniRule annotationAdd BLAST21
Transmembranei439 – 459HelicalUniRule annotationAdd BLAST21
Transmembranei464 – 484HelicalUniRule annotationAdd BLAST21
Transmembranei493 – 513HelicalUniRule annotationAdd BLAST21
Transmembranei533 – 553HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002087971 – 553Putative transport protein YidEAdd BLAST553

Proteomic databases

PaxDbiP60872.
PRIDEiP60872.

Interactioni

Protein-protein interaction databases

BioGridi4260808. 166 interactors.
DIPiDIP-12444N.
IntActiP60872. 1 interactor.
MINTiMINT-1257845.
STRINGi511145.b3685.

Structurei

3D structure databases

ProteinModelPortaliP60872.
SMRiP60872.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini191 – 276RCK C-terminal 1UniRule annotationAdd BLAST86
Domaini279 – 361RCK C-terminal 2UniRule annotationAdd BLAST83

Sequence similaritiesi

Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily. [View classification]UniRule annotation
Contains 2 RCK C-terminal domains.UniRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105D0C. Bacteria.
COG2985. LUCA.
HOGENOMiHOG000013110.
InParanoidiP60872.
KOiK07085.
OMAiELGDYLH.
PhylomeDBiP60872.

Family and domain databases

Gene3Di3.30.70.1450. 2 hits.
HAMAPiMF_01016. YidE. 1 hit.
InterProiIPR006037. RCK_C.
IPR023018. Transpt_YidE_put.
IPR006512. YidE_YbjL.
[Graphical view]
PfamiPF06826. Asp-Al_Ex. 2 hits.
PF02080. TrkA_C. 2 hits.
[Graphical view]
SUPFAMiSSF116726. SSF116726. 2 hits.
TIGRFAMsiTIGR01625. YidE_YbjL_dupl. 2 hits.
PROSITEiPS51202. RCK_C. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P60872-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDIALTVSI LALVAVVGLF IGNVKFRGIG LGIGGVLFGG IIVGHFVSQA
60 70 80 90 100
GMTLSSDMLH VIQEFGLILF VYTIGIQVGP GFFASLRVSG LRLNLFAVLI
110 120 130 140 150
VIIGGLVTAI LHKLFDIPLP VVLGIFSGAV TNTPALGAGQ QILRDLGTPM
160 170 180 190 200
EMVDQMGMSY AMAYPFGICG ILFTMWMLRV IFRVNVETEA QQHESSRTNG
210 220 230 240 250
GALIKTINIR VENPNLHDLA IKDVPILNGD KIICSRLKRE ETLKVPSPDT
260 270 280 290 300
IIQLGDLLHL VGQPADLHNA QLVIGQEVDT SLSTKGTDLR VERVVVTNEN
310 320 330 340 350
VLGKRIRDLH FKERYDVVIS RLNRAGVELV ASGDISLQFG DILNLVGRPS
360 370 380 390 400
AIDAVANVLG NAQQKLQQVQ MLPVFIGIGL GVLLGSIPVF VPGFPAALKL
410 420 430 440 450
GLAGGPLIMA LILGRIGSIG KLYWFMPPSA NLALRELGIV LFLSVVGLKS
460 470 480 490 500
GGDFVNTLVN GEGLSWIGYG ALITAVPLIT VGILARMLAK MNYLTMCGML
510 520 530 540 550
AGSMTDPPAL AFANNLHPTS GAAALSYATV YPLVMFLRII TPQLLAVLFW

SIG
Length:553
Mass (Da):58,939
Last modified:April 13, 2004 - v1
Checksum:i688CE1DC1F2A1F3B
GO

Sequence cautioni

The sequence AAA62037 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti339 – 347FGDILNLVG → RTDRNAKLL in AAA24426 (PubMed:1356969).Curated9

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10328 Genomic DNA. Translation: AAA62037.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76708.2.
AP009048 Genomic DNA. Translation: BAE77609.1.
M94104 Genomic DNA. Translation: AAA24426.1.
PIRiF65170.
RefSeqiNP_418140.4. NC_000913.3.
WP_001279752.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76708; AAC76708; b3685.
BAE77609; BAE77609; BAE77609.
GeneIDi948193.
KEGGiecj:JW3662.
eco:b3685.
PATRICi32122863. VBIEscCol129921_3807.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10328 Genomic DNA. Translation: AAA62037.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76708.2.
AP009048 Genomic DNA. Translation: BAE77609.1.
M94104 Genomic DNA. Translation: AAA24426.1.
PIRiF65170.
RefSeqiNP_418140.4. NC_000913.3.
WP_001279752.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP60872.
SMRiP60872.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260808. 166 interactors.
DIPiDIP-12444N.
IntActiP60872. 1 interactor.
MINTiMINT-1257845.
STRINGi511145.b3685.

Proteomic databases

PaxDbiP60872.
PRIDEiP60872.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76708; AAC76708; b3685.
BAE77609; BAE77609; BAE77609.
GeneIDi948193.
KEGGiecj:JW3662.
eco:b3685.
PATRICi32122863. VBIEscCol129921_3807.

Organism-specific databases

EchoBASEiEB1498.
EcoGeneiEG11536. yidE.

Phylogenomic databases

eggNOGiENOG4105D0C. Bacteria.
COG2985. LUCA.
HOGENOMiHOG000013110.
InParanoidiP60872.
KOiK07085.
OMAiELGDYLH.
PhylomeDBiP60872.

Enzyme and pathway databases

BioCyciEcoCyc:EG11536-MONOMER.
ECOL316407:JW3662-MONOMER.

Miscellaneous databases

PROiP60872.

Family and domain databases

Gene3Di3.30.70.1450. 2 hits.
HAMAPiMF_01016. YidE. 1 hit.
InterProiIPR006037. RCK_C.
IPR023018. Transpt_YidE_put.
IPR006512. YidE_YbjL.
[Graphical view]
PfamiPF06826. Asp-Al_Ex. 2 hits.
PF02080. TrkA_C. 2 hits.
[Graphical view]
SUPFAMiSSF116726. SSF116726. 2 hits.
TIGRFAMsiTIGR01625. YidE_YbjL_dupl. 2 hits.
PROSITEiPS51202. RCK_C. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYIDE_ECOLI
AccessioniPrimary (citable) accession number: P60872
Secondary accession number(s): P29211
, P76732, Q2M7Z7, Q8X537
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: April 13, 2004
Last modified: November 30, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.