Reviewed, UniProtKB/Swiss-Prot P60820 (SELD_METMP)

Names and origin

Protein names

Recommended name:
    Selenide, water dikinase
    EC=2.7.9.3
Alternative name(s):
    Selenophosphate synthetase
    Selenium donor protein

Gene names

Name:	selD
Ordered Locus Names:	MMP0904

Organism

Methanococcus maripaludis [Complete proteome] [HAMAP]

Taxonomic identifier

39152 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	335 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Synthesizes selenophosphate from selenide and ATP By similarity. HAMAP MF_00625
Catalytic activity	ATP + selenide + H2O = AMP + selenophosphate + phosphate. HAMAP MF_00625
Cofactor	Magnesium By similarity. HAMAP MF_00625
Sequence similarities	Belongs to the selenophosphate synthetase 1 family. Class I subfamily.
Sequence caution	The sequence CAF30460.1 differs from that shown. Reason: Erroneous termination at position 7. Translated as Sec.

Ontologies

Keywords
Coding sequence diversity	Selenocysteine
Ligand	ATP-binding Magnesium Nucleotide-binding Selenium
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP selenide, water dikinase activity Inferred from electronic annotation. Source: HAMAP selenium binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 335	335	Selenide, water dikinase HAMAP MF_00625		PRO_0000127647
Regions
	Nucleotide binding	235 – 241	7	ATP Potential
Sites
	Active site	7	1	Potential
	Site	10	1	Important for catalytic activity By similarity
Amino acid modifications
	Non-standard residue	7	1	Selenocysteine Potential

Sequences

	Sequence		Length	Mass (Da)
	P60820-1 [UniParc]. Last modified February 26, 2008. Version 2. Checksum: D0E7FE9BE8BBC5FA	FASTA	335	36,152
	10 20 30 40 50 60 MVTLHGUACK LPDTELENLV KGIISEDDLK HAKVGLGDDA AVVIKNGMAI VKTIDVFTPI 70 80 90 100 110 120 VDDPYLQGRI AACNSTSDVY AMGISEIIGG LVFLGIPPEL PVPVAKKMLQ GFQDFCREND 130 140 150 160 170 180 TTIIGGHTIL NPWPLIGGSI TGVGKEEDIL TKAGCKNGDV LILTKPLGNQ SAMALSRVTE 190 200 210 220 230 240 EFEDLIDIPK EEQKYIFEKT IELMTTSNRI ALLHLRELEN ELGEKIANAM TDVTGFGILG 250 260 270 280 290 300 HSQEMAEQSD VEIEISCLPV IKGTPELASL FGHALCSGKG AETAGGLLIS TKPEYKDKLI 310 320 330 QKFKENNVYA FEVGKIVNNG VGIAKLSENV EILEI

References

[1]

"Complete genome sequence of the genetically tractable hydrogenotrophic methanogen Methanococcus maripaludis." Hendrickson E.L., Kaul R., Zhou Y., Bovee D., Chapman P., Chung J., Conway de Macario E., Dodsworth J.A., Gillett W., Graham D.E., Hackett M., Haydock A.K., Kang A., Land M.L., Levy R., Lie T.J., Major T.A., Moore B.C. , Porat I., Palmeiri A., Rouse G., Saenphimmachak C., Soell D., Van Dien S., Wang T., Whitman W.B., Xia Q., Zhang Y., Larimer F.W., Olson M.V., Leigh J.A. J. Bacteriol. 186:6956-6969(2004) [PubMed: 15466049] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S2 / LL.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX950229 Genomic DNA. Translation: CAF30460.1. Sequence problems.
3D structure databases
ModBase	Search...
Genome annotation databases
GenomeReviews	Gene locus MMP0904 in contig BX950229_GR.
KEGG	mmp:MMP0904.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG383791.
OMA	CRENDTT.
Enzyme and pathway databases
BioCyc	MMAR267377:MMP0904-MONOMER.
BRENDA	2.7.9.3. 20956.
Family and domain databases
HAMAP	MF_00625. SelD. [Tree]
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR016188. PurM_N-like. IPR004536. SelD. [Graphical view]
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
PIRSF	PIRSF036407. Selenphspht_syn. 1 hit.
TIGRFAMs	TIGR00476. selD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SELD_METMP

Accession

Primary (citable) accession number: P60820

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	February 26, 2008
Last modified:	February 9, 2010
This is version 34 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)