P60781 (RNP3_METMP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 3
Short name=RNase P component 3
EC=3.1.26.5

Gene names

Name:	rnp3
Ordered Locus Names:	MMP0430

Organism

Methanococcus maripaludis (strain S2 / LL) [Complete proteome] [HAMAP]

Taxonomic identifier

267377 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus › Methanococcus maripaludis

Protein attributes

Sequence length	232 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00756
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00756
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Molecular_function	ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 232	232	Ribonuclease P protein component 3 HAMAP-Rule MF_00756		PRO_0000140042

Sequences

	Sequence		Length	Mass (Da)
	P60781 [UniParc]. Last modified April 13, 2004. Version 1. Checksum: 1BE3FFFB9096C7EA	FASTA	232	26,452
	10 20 30 40 50 60 MLEGIFDINH VFDEEGIKTL KRFGWDGSVA VQNHNEYSEE KINTAVEYGE NCEFKVYSGV 70 80 90 100 110 120 KISTKNQNEM EKAVKKYRNK VDILLVEGGD VKINRRVLEM NDVDILSTPE LNRMDNGLDH 130 140 150 160 170 180 ILARLGSTNR VAVELNFGNL LKSKNYDRSK ILWAFQRNLK LSKKYDTPVV ISSGANDIYG 190 200 210 220 230 IKAPGDLRGF LNTVADPLYS KKIIETTSKI IDYRLYLKNK NVLMPGLEIV EE

References

[1]

"Complete genome sequence of the genetically tractable hydrogenotrophic methanogen Methanococcus maripaludis." Hendrickson E.L., Kaul R., Zhou Y., Bovee D., Chapman P., Chung J., Conway de Macario E., Dodsworth J.A., Gillett W., Graham D.E., Hackett M., Haydock A.K., Kang A., Land M.L., Levy R., Lie T.J., Major T.A., Moore B.C. , Porat I., Palmeiri A., Rouse G., Saenphimmachak C., Soell D., Van Dien S., Wang T., Whitman W.B., Xia Q., Zhang Y., Larimer F.W., Olson M.V., Leigh J.A. J. Bacteriol. 186:6956-6969(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S2 / LL.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX950229 Genomic DNA. Translation: CAF29986.1.
RefSeq	NP_987550.1. NC_005791.1.
3D structure databases
ProteinModelPortal	P60781.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-59366N.
STRING	267377.MMP0430.
Protocols and materials databases
DNASU	2762077.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAF29986; CAF29986; MMP0430.
GeneID	2762077.
KEGG	mmp:MMP0430.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1603.
HOGENOM	HOG000296348.
KO	K03539.
OMA	STPELNR.
ProtClustDB	CLSK876467.
Enzyme and pathway databases
BioCyc	MMAR267377:GJ77-457-MONOMER.
Family and domain databases
HAMAP	MF_00756. RNase_P_3.
InterPro	IPR016195. Pol/histidinol_Pase-like. IPR023539. RNase_P_comp-3_arc. IPR002738. RNase_P_p30. [Graphical view]
Pfam	PF01876. RNase_P_p30. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP3_METMP

Accession

Primary (citable) accession number: P60781

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	April 13, 2004
Last modified:	May 1, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program