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Protein

Protein TsgA

Gene

tsgA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • response to selenite ion Source: EcoCyc
  • transmembrane transport Source: InterPro

Enzyme and pathway databases

BioCyciEcoCyc:YHFC-MONOMER

Protein family/group databases

TCDBi2.A.1.7.14 the major facilitator superfamily (mfs)

Names & Taxonomyi

Protein namesi
Recommended name:
Protein TsgA
Gene namesi
Name:tsgA
Synonyms:gutS, yhfC, yhfH
Ordered Locus Names:b3364, JW3327
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11262 tsgA

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 10CytoplasmicSequence analysis10
Transmembranei11 – 31HelicalSequence analysisAdd BLAST21
Topological domaini32 – 50PeriplasmicSequence analysisAdd BLAST19
Transmembranei51 – 71HelicalSequence analysisAdd BLAST21
Topological domaini72 – 77CytoplasmicSequence analysis6
Transmembranei78 – 98HelicalSequence analysisAdd BLAST21
Topological domaini99 – 100PeriplasmicSequence analysis2
Transmembranei101 – 121HelicalSequence analysisAdd BLAST21
Topological domaini122 – 133CytoplasmicSequence analysisAdd BLAST12
Transmembranei134 – 154HelicalSequence analysisAdd BLAST21
Topological domaini155 – 161PeriplasmicSequence analysis7
Transmembranei162 – 182HelicalSequence analysisAdd BLAST21
Topological domaini183 – 205CytoplasmicSequence analysisAdd BLAST23
Transmembranei206 – 226HelicalSequence analysisAdd BLAST21
Topological domaini227 – 244PeriplasmicSequence analysisAdd BLAST18
Transmembranei245 – 265HelicalSequence analysisAdd BLAST21
Topological domaini266 – 272CytoplasmicSequence analysis7
Transmembranei273 – 293HelicalSequence analysisAdd BLAST21
Topological domaini294 – 296PeriplasmicSequence analysis3
Transmembranei297 – 317HelicalSequence analysisAdd BLAST21
Topological domaini318 – 331CytoplasmicSequence analysisAdd BLAST14
Transmembranei332 – 352HelicalSequence analysisAdd BLAST21
Topological domaini353 – 360PeriplasmicSequence analysis8
Transmembranei361 – 381HelicalSequence analysisAdd BLAST21
Topological domaini382 – 393CytoplasmicSequence analysisAdd BLAST12

GO - Cellular componenti

  • integral component of plasma membrane Source: EcoCyc
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002064941 – 393Protein TsgAAdd BLAST393

Proteomic databases

PaxDbiP60778
PRIDEiP60778

Expressioni

Inductioni

By selenite or tellurite. Maximal expression was detected at concentrations of 10.0 and 0.5 micrograms/ml for sodium selenite and sodium tellurite, respectively.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4261086, 10 interactors
STRINGi316385.ECDH10B_3540

Structurei

3D structure databases

ProteinModelPortaliP60778
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4106DTQ Bacteria
COG0477 LUCA
HOGENOMiHOG000290517
InParanoidiP60778
KOiK06141
OMAiRFGFVLM
PhylomeDBiP60778

Family and domain databases

CDDicd06174 MFS, 1 hit
HAMAPiMF_01044 MFS_TsgA, 1 hit
InterProiView protein in InterPro
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
IPR023528 MFS_TsgA
PANTHERiPTHR43702:SF2 PTHR43702:SF2, 1 hit
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit

Sequencei

Sequence statusi: Complete.

P60778-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTNSNRIKLT WISFLSYALT GALVIVTGMV MGNIADYFNL PVSSMSNTFT
60 70 80 90 100
FLNAGILISI FLNAWLMEIV PLKTQLRFGF LLMVLAVAGL MFSHSLALFS
110 120 130 140 150
AAMFILGVVS GITMSIGTFL VTQMYEGRQR GSRLLFTDSF FSMAGMIFPM
160 170 180 190 200
IAAFLLARSI EWYWVYACIG LVYVAIFILT FGCEFPALGK HAPKTDAPVE
210 220 230 240 250
KEKWGIGVLF LSVAALCYIL GQLGFISWVP EYAKGLGMSL NDAGTLVSNF
260 270 280 290 300
WMSYMVGMWA FSFILRFFDL QRILTVLAGL AAILMYVFNT GTPAHMAWSI
310 320 330 340 350
LALGFFSSAI YTTIITLGSQ QTKVPSPKLV NFVLTCGTIG TMLTFVVTGP
360 370 380 390
IVEHSGPQAA LLTANGLYAV VFVMCFLLGF VSRHRQHNTL TSH
Length:393
Mass (Da):43,166
Last modified:April 13, 2004 - v1
Checksum:i75445C6136809691
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA Translation: AAA58161.1
U00096 Genomic DNA Translation: AAC76389.1
AP009048 Genomic DNA Translation: BAE77926.1
M28363 Genomic DNA Translation: AAA23771.2
X14202 Genomic DNA No translation available.
PIRiG65130
RefSeqiNP_417823.1, NC_000913.3
WP_000185247.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76389; AAC76389; b3364
BAE77926; BAE77926; BAE77926
GeneIDi947869
KEGGiecj:JW3327
eco:b3364
PATRICifig|1411691.4.peg.3365

Similar proteinsi

Entry informationi

Entry nameiTSGA_ECOLI
AccessioniPrimary (citable) accession number: P60778
Secondary accession number(s): P21229, P37612, Q2M730
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: April 13, 2004
Last modified: March 28, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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