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P60656

- SPEB_SALTY

UniProt

P60656 - SPEB_SALTY

Protein

Agmatinase

Gene

speB

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 1 (29 Mar 2004)
      Previous versions | rss
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    Functioni

    Catalyzes the formation of putrescine from agmatine.UniRule annotation

    Catalytic activityi

    Agmatine + H2O = putrescine + urea.UniRule annotation

    Cofactori

    Manganese.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi126 – 1261ManganeseUniRule annotation
    Metal bindingi149 – 1491ManganeseUniRule annotation
    Metal bindingi151 – 1511ManganeseUniRule annotation
    Metal bindingi153 – 1531ManganeseUniRule annotation
    Metal bindingi230 – 2301ManganeseUniRule annotation
    Metal bindingi232 – 2321ManganeseUniRule annotation

    GO - Molecular functioni

    1. agmatinase activity Source: UniProtKB-HAMAP
    2. manganese ion binding Source: InterPro

    GO - Biological processi

    1. putrescine biosynthetic process from arginine Source: UniProtKB-UniPathway
    2. spermidine biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Polyamine biosynthesis, Putrescine biosynthesis, Spermidine biosynthesis

    Keywords - Ligandi

    Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciSENT99287:GCTI-3098-MONOMER.
    UniPathwayiUPA00534; UER00287.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    AgmatinaseUniRule annotation (EC:3.5.3.11UniRule annotation)
    Alternative name(s):
    Agmatine ureohydrolaseUniRule annotation
    Short name:
    AUHUniRule annotation
    Gene namesi
    Name:speBUniRule annotation
    Ordered Locus Names:STM3078
    OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
    Taxonomic identifieri99287 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
    ProteomesiUP000001014: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 306306AgmatinasePRO_0000173742Add
    BLAST

    Proteomic databases

    PRIDEiP60656.

    Interactioni

    Protein-protein interaction databases

    STRINGi99287.STM3078.

    Structurei

    3D structure databases

    ProteinModelPortaliP60656.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the arginase family. Agmatinase subfamily.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000204320.
    KOiK01480.
    OMAiKPDYSLY.
    OrthoDBiEOG6R2GW5.
    PhylomeDBiP60656.

    Family and domain databases

    Gene3Di3.40.800.10. 1 hit.
    HAMAPiMF_01418. SpeB.
    InterProiIPR023694. Agmatinase.
    IPR005925. Agmatinase-rel.
    IPR006035. Ureohydrolase.
    IPR023696. Ureohydrolase_domain.
    IPR020855. Ureohydrolase_Mn_BS.
    [Graphical view]
    PANTHERiPTHR11358. PTHR11358. 1 hit.
    PfamiPF00491. Arginase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF036979. Arginase. 1 hit.
    TIGRFAMsiTIGR01230. agmatinase. 1 hit.
    PROSITEiPS01053. ARGINASE_1. 1 hit.
    PS51409. ARGINASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P60656-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSTLGHQYDN SLVSNAFGFL RLPMNFQPYD SDADWVITGV PFDMATSGRA    50
    GGRHGPAAIR QVSTNLAWEH HRFPWNFDMR ERLNVVDCGD LVYAFGDARE 100
    MSEKLQAHAE KLLSAGKRML SFGGDHFVTL PLLRAHAKHF GKMALVHFDA 150
    HTDTYANGCE FDHGTMFYTA PKEGLIDPHH SVQIGIRTEF DKDNGFTVLD 200
    ACQVNDRGVD DILAQVKQIV GDMPVYLTFD IDCLDPAFAP GTGTPVIGGL 250
    TSDRAIKLVR GLKDLNIVGM DVVEVAPAYD QSEITALAAA TLALEMLYIQ 300
    AAKKGE 306
    Length:306
    Mass (Da):33,603
    Last modified:March 29, 2004 - v1
    Checksum:i6C26A30691F2C3D3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006468 Genomic DNA. Translation: AAL21953.1.
    RefSeqiNP_461994.1. NC_003197.1.

    Genome annotation databases

    EnsemblBacteriaiAAL21953; AAL21953; STM3078.
    GeneIDi1254601.
    KEGGistm:STM3078.
    PATRICi32384905. VBISalEnt20916_3261.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006468 Genomic DNA. Translation: AAL21953.1 .
    RefSeqi NP_461994.1. NC_003197.1.

    3D structure databases

    ProteinModelPortali P60656.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 99287.STM3078.

    Proteomic databases

    PRIDEi P60656.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL21953 ; AAL21953 ; STM3078 .
    GeneIDi 1254601.
    KEGGi stm:STM3078.
    PATRICi 32384905. VBISalEnt20916_3261.

    Phylogenomic databases

    HOGENOMi HOG000204320.
    KOi K01480.
    OMAi KPDYSLY.
    OrthoDBi EOG6R2GW5.
    PhylomeDBi P60656.

    Enzyme and pathway databases

    UniPathwayi UPA00534 ; UER00287 .
    BioCyci SENT99287:GCTI-3098-MONOMER.

    Family and domain databases

    Gene3Di 3.40.800.10. 1 hit.
    HAMAPi MF_01418. SpeB.
    InterProi IPR023694. Agmatinase.
    IPR005925. Agmatinase-rel.
    IPR006035. Ureohydrolase.
    IPR023696. Ureohydrolase_domain.
    IPR020855. Ureohydrolase_Mn_BS.
    [Graphical view ]
    PANTHERi PTHR11358. PTHR11358. 1 hit.
    Pfami PF00491. Arginase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF036979. Arginase. 1 hit.
    TIGRFAMsi TIGR01230. agmatinase. 1 hit.
    PROSITEi PS01053. ARGINASE_1. 1 hit.
    PS51409. ARGINASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: LT2 / SGSC1412 / ATCC 700720.

    Entry informationi

    Entry nameiSPEB_SALTY
    AccessioniPrimary (citable) accession number: P60656
    Secondary accession number(s): Q8XG05
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 29, 2004
    Last sequence update: March 29, 2004
    Last modified: October 1, 2014
    This is version 71 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3