50S ribosomal protein L10e - Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

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P60617 (RL10_HALMA) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 66. History...

Clusters with 100%, 90%, 50% identity |

Documents (3) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
50S ribosomal protein L10e

Gene names

Name:	rpl10e
Ordered Locus Names:	rrnAC2357

Organism

Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui) [Complete proteome] [HAMAP]

Taxonomic identifier

272569 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Haloarcula

Protein attributes

Sequence length	177 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	This is 1 of 5 proteins that mediate the attachment of the 5S rRNA onto the large ribosomal subunit, stabilizing the orientation of adjacent RNA domains. Modeling places the A and P site tRNAs in close proximity to this protein. HAMAP MF_00448
Subunit structure	Part of the 50S ribosomal subunit. Weakly binds 5S rRNA. Probably binds the A and P site tRNAs. Ref.2 Ref.3 Ref.4 Ref.5 Ref.6 Ref.7 Ref.8 Ref.9
Sequence similarities	Belongs to the ribosomal protein L10e family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding tRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	3D-structure Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 177

177

50S ribosomal protein L10e HAMAP MF_00448

PRO_0000147132

Secondary structure

177

Helix Strand Turn

Details...

Sequences

Sequence

Length

Mass (Da)

Tools

P60617 [UniParc].

Last modified January 4, 2005. Version 2.
Checksum: E7A72FE3683D2BDB
Show »

FASTA

177

19,908

        10         20         30         40         50         60 
MSDKPASMYR DIDKPAYTRR EYITGIPGSK IAQHKMGRKQ KDADDYPVQI SLIVEETVQL 

        70         80         90        100        110        120 
RHGSLEASRL SANRHLIKEL GEEGDYKMTL RKFPHQVLRE NKQATGAGAD RVSDGMRAAF 

       130        140        150        160        170 
GKIVGTAARV QAGEQLFTAY CNVEDAEHVK EAFRRAYNKI TPSCRIKVER GEELLIA

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of Haloarcula marismortui: a halophilic archaeon from the Dead Sea." Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W., Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E., Hood L., Ng W.V. Genome Res. 14:2221-2234(2004) [PubMed: 15520287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
[2]	"The complete atomic structure of the large ribosomal subunit at 2.4 A resolution." Ban N., Nissen P., Hansen J., Moore P.B., Steitz T.A. Science 289:905-920(2000) [PubMed: 10937989] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF THE 50S SUBUNIT. Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
[3]	"The structural basis of ribosome activity in peptide bond synthesis." Nissen P., Hansen J., Ban N., Moore P.B., Steitz T.A. Science 289:920-930(2000) [PubMed: 10937990] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF THE 50S SUBUNIT. Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
[4]	"A pre-translocational intermediate in protein synthesis observed in crystals of enzymatically active 50S subunits." Schmeing T.M., Seila A.C., Hansen J.L., Freeborn B., Soukup J.K., Scaringe S.A., Strobel S.A., Moore P.B., Steitz T.A. Nat. Struct. Biol. 9:225-230(2002) [PubMed: 11828326] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.1 ANGSTROMS) OF THE 50S SUBUNIT. Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
[5]	"The kink-turn: a new RNA secondary structure motif." Klein D.J., Schmeing T.M., Moore P.B., Steitz T.A. EMBO J. 20:4214-4221(2001) [PubMed: 11483524] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF THE 50S SUBUNIT. Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
[6]	"The structures of four macrolide antibiotics bound to the large ribosomal subunit." Hansen J.L., Ippolito J.A., Ban N., Nissen P., Moore P.B., Steitz T.A. Mol. Cell 10:117-128(2002) [PubMed: 12150912] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH FOUR MACROLIDE ANTIBIOTICS. Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
[7]	"Structural insights into peptide bond formation." Hansen J.L., Schmeing T.M., Moore P.B., Steitz T.A. Proc. Natl. Acad. Sci. U.S.A. 99:11670-11675(2002) [PubMed: 12185246] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF THE 50S SUBUNIT. Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
[8]	"Structures of five antibiotics bound at the peptidyl transferase center of the large ribosomal subunit." Hansen J.L., Moore P.B., Steitz T.A. J. Mol. Biol. 330:1061-1075(2003) [PubMed: 12860128] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH FIVE ANTIBIOTICS AT THE PEPTIDYL TRANSFERASE CENTER. Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
[9]	"Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit." Schmeing T.M., Moore P.B., Steitz T.A. RNA 9:1345-1352(2003) [PubMed: 14561884] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF THE 50S SUBUNIT WITH TWO DIFFERENT E SITE SUBSTRATES.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AY596297 Genomic DNA. Translation: AAV47175.1.

RefSeq

YP_136882.1. NC_006396.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1FFK	X-ray	2.40	F	14-129	[»]
1JJ2	X-ray	2.40	H	14-130	[»]
1K73	X-ray	3.01	J	14-130	[»]
1K8A	X-ray	3.00	J	14-130	[»]
1K9M	X-ray	3.00	J	14-130	[»]
1KC8	X-ray	3.01	J	14-130	[»]
1KD1	X-ray	3.00	J	14-130	[»]
1KQS	X-ray	3.10	H	14-130	[»]
1M1K	X-ray	3.20	J	14-130	[»]
1M90	X-ray	2.80	J	14-130	[»]
1N8R	X-ray	3.00	J	14-130	[»]
1NJI	X-ray	3.00	J	14-130	[»]
1Q7Y	X-ray	3.20	J	14-130	[»]
1Q81	X-ray	2.95	J	14-130	[»]
1Q82	X-ray	2.98	J	14-130	[»]
1Q86	X-ray	3.00	J	14-130	[»]
1QVF	X-ray	3.10	H	14-130	[»]
1QVG	X-ray	2.90	H	14-130	[»]
1S72	X-ray	2.40	H	4-166	[»]
1VQ4	X-ray	2.70	H	4-166	[»]
1VQ5	X-ray	2.60	H	4-166	[»]
1VQ6	X-ray	2.70	H	4-166	[»]
1VQ7	X-ray	2.50	H	4-166	[»]
1VQ8	X-ray	2.20	H	4-166	[»]
1VQ9	X-ray	2.40	H	4-166	[»]
1VQK	X-ray	2.30	H	4-166	[»]
1VQL	X-ray	2.30	H	4-166	[»]
1VQM	X-ray	2.30	H	4-166	[»]
1VQN	X-ray	2.40	H	4-166	[»]
1VQO	X-ray	2.20	H	4-166	[»]
1VQP	X-ray	2.25	H	4-166	[»]
1W2B	X-ray	3.50	H	14-130	[»]
1YHQ	X-ray	2.40	H	1-177	[»]
1YI2	X-ray	2.65	H	1-177	[»]
1YIJ	X-ray	2.60	H	1-177	[»]
1YIT	X-ray	2.80	H	1-177	[»]
1YJ9	X-ray	2.90	H	1-177	[»]
1YJN	X-ray	3.00	H	1-177	[»]
1YJW	X-ray	2.90	H	1-177	[»]
2OTJ	X-ray	2.90	H	4-166	[»]
2OTL	X-ray	2.70	H	4-166	[»]
2QA4	X-ray	3.00	H	4-166	[»]
2QEX	X-ray	2.90	H	1-166	[»]
3CC2	X-ray	2.40	H	1-177	[»]
3CC4	X-ray	2.70	H	1-177	[»]
3CC7	X-ray	2.70	H	1-177	[»]
3CCE	X-ray	2.75	H	1-177	[»]
3CCJ	X-ray	2.70	H	1-177	[»]
3CCL	X-ray	2.90	H	1-177	[»]
3CCM	X-ray	2.55	H	1-177	[»]
3CCQ	X-ray	2.90	H	1-177	[»]
3CCR	X-ray	3.00	H	1-177	[»]
3CCS	X-ray	2.95	H	1-177	[»]
3CCU	X-ray	2.80	H	1-177	[»]
3CCV	X-ray	2.90	H	1-177	[»]
3CD6	X-ray	2.75	H	1-177	[»]
3CMA	X-ray	2.80	H	1-177	[»]
3CME	X-ray	2.95	H	1-177	[»]
3CPW	X-ray	2.70	H	1-177	[»]
3G4S	X-ray	3.20	H	1-177	[»]
3G6E	X-ray	2.70	H	1-177	[»]
3G71	X-ray	2.85	H	1-177	[»]
3I55	X-ray	3.11	H	1-174	[»]
3I56	X-ray	2.90	H	1-174	[»]

ProteinModelPortal

P60617.

SMR

P60617. Positions 4-174.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

3130436.

GenomeReviews

Gene locus rrnAC2357 in contig AY596297_GR.

KEGG

hma:rrnAC2357.

NMPDR

fig|272569.1.peg.2163.

Organism-specific databases

CMR

Search...

Phylogenomic databases

HOGENOM

HBG512729.

OMA

RENPMAT.

PhylomeDB

P60617.

ProtClustDB

PRK04199.

Enzyme and pathway databases

BioCyc

HMAR272569:RRNAC2357-MONOMER.

Family and domain databases

HAMAP

MF_00448. Ribosomal_L10e.
[Tree]

InterPro

IPR001197. Ribosomal_L10e.
IPR016180. Ribosomal_L10e/L16.
IPR022981. Ribosomal_L10e_arc.
IPR018255. Ribosomal_L10e_CS.
[Graphical view]

K02866.

Pfam

PF00252. Ribosomal_L16. 1 hit.
[Graphical view]

PIRSF

PIRSF005590. Ribosomal_L10. 1 hit.

SUPFAM

SSF54686. Ribosomal_L10e/L16. 1 hit.

PROSITE

PS01257. RIBOSOMAL_L10E. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

RL10_HALMA

Accession

Primary (citable) accession number: P60617
Secondary accession number(s): Q5UZX7

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2004
Last sequence update:	January 4, 2005
Last modified:	December 14, 2011
This is version 66 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Secondary structure

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry information

Relevant documents