ID   GBRL2_RAT               Reviewed;         117 AA.
AC   P60522; O08765; Q9DCP8; Q9UQF7;
DT   01-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2004, sequence version 1.
DT   13-OCT-2009, entry version 42.
DE   RecName: Full=Gamma-aminobutyric acid receptor-associated protein-like 2;
DE   AltName: Full=GABA(A) receptor-associated protein-like 2;
DE   AltName: Full=Golgi-associated ATPase enhancer of 16 kDa;
DE            Short=GATE-16;
DE   AltName: Full=Ganglioside expression factor 2;
DE            Short=GEF-2;
GN   Name=Gabarapl2; Synonyms=Gef2;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Wistar; TISSUE=Brain;
RA   Ogura K.;
RT   "Expression cloning of a cDNA encoding a ganglioside expression
RT   factor-2 (GEF-2).";
RL   Submitted (MAY-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Liver, and Pituitary;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Involved in intra-Golgi traffic. Modulates intra-Golgi
CC       transport through coupling between NSF activity and SNAREs
CC       activation. It first stimulates the ATPase activity of NSF which
CC       in turn stimulates the association with GOSR1 (By similarity).
CC   -!- SUBUNIT: Monomer. Interacts with GABRG2, ULK1, NSF, GOSR1 and
CC       beta-tubulin (By similarity).
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus (By similarity).
CC   -!- PTM: Phosphorylated upon DNA damage, probably by ATM or ATR (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the MAP1 LC3 family.
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DR   EMBL; AB003515; BAA19975.1; -; mRNA.
DR   EMBL; BC058145; AAH58145.1; -; mRNA.
DR   EMBL; BC088139; AAH88139.1; -; mRNA.
DR   IPI; IPI00195649; -.
DR   RefSeq; NP_073197.1; -.
DR   UniGene; Rn.64537; -.
DR   SMR; P60522; 1-117.
DR   Ensembl; ENSRNOT00000026274; ENSRNOP00000026274; ENSRNOG00000019425; Rattus norvegicus.
DR   Ensembl; ENSRNOT00000047078; ENSRNOP00000043130; ENSRNOG00000033345; Rattus norvegicus.
DR   Ensembl; ENSRNOT00000048998; ENSRNOP00000040067; ENSRNOG00000019425; Rattus norvegicus.
DR   GeneID; 64670; -.
DR   KEGG; rno:64670; -.
DR   UCSC; NM_022706; rat.
DR   CTD; 64670; -.
DR   RGD; 620510; Gabarapl2.
DR   HOVERGEN; P60522; -.
DR   NextBio; 613665; -.
DR   ArrayExpress; P60522; -.
DR   Genevestigator; P60522; -.
DR   GermOnline; ENSRNOG00000019425; Rattus norvegicus.
DR   GermOnline; ENSRNOG00000033345; Rattus norvegicus.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR004241; MAP1_LC3.
DR   PANTHER; PTHR10969; MAP1_LC3; 1.
DR   Pfam; PF02991; MAP1_LC3; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Golgi apparatus; Phosphoprotein; Protein transport;
KW   Transport.
FT   CHAIN         1    117       Gamma-aminobutyric acid receptor-
FT                                associated protein-like 2.
FT                                /FTId=PRO_0000212375.
FT   REGION        1     22       Interaction with beta-tubulin (By
FT                                similarity).
FT   REGION       36     68       Interaction with GABRG2 (Potential).
FT   MOD_RES      10     10       Phosphoserine (By similarity).
FT   MOD_RES      24     24       N6-acetyllysine (By similarity).
FT   MOD_RES      39     39       Phosphoserine (By similarity).
SQ   SEQUENCE   117 AA;  13667 MW;  17ACB540FD5B975B CRC64;
     MKWMFKEDHS LEHRCVESAK IRAKYPDRVP VIVEKVSGSQ IVDIDKRKYL VPSDITVAQF
     MWIIRKRIQL PSEKAIFLFV DKTVPQSSLT MGQLYEKEKD EDGFLYVAYS GENTFGF
//