50S ribosomal protein L21 - Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

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P60492 (RL21_THET8) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 63. History...

Clusters with 100%, 90%, 50% identity |

Documents (3) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
50S ribosomal protein L21

Gene names

Name:	rplU
Ordered Locus Names:	TTHA1783

Organism

Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

Taxonomic identifier

300852 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus

Protein attributes

Sequence length	101 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	This protein binds to 23S rRNA in the presence of protein L20 By similarity. Found on the solvent side of the large subunit. HAMAP MF_01363
Subunit structure	Contacts protein L20 By similarity. Part of the 50S ribosomal subunit. HAMAP MF_01363
Sequence similarities	Belongs to the ribosomal protein L21P family.
Mass spectrometry	Molecular mass is 11048 Da from positions 1 - 101. Determined by MALDI. Ref.3

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	3D-structure Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 101

101

50S ribosomal protein L21 HAMAP MF_01363

PRO_0000181018

Secondary structure

101

Helix Strand Turn

Details...

Sequences

Sequence

Length

Mass (Da)

Tools

P60492 [UniParc].

Last modified March 29, 2005. Version 2.
Checksum: 3117549029950A0C
Show »

FASTA

101

11,047

        10         20         30         40         50         60 
MFAIVKTGGK QYRVEPGLKL RVEKLDAEPG ATVELPVLLL GGEKTVVGTP VVEGASVVAE 

        70         80         90        100 
VLGHGRGKKI LVSKFKAKVQ YRRKKGHRQP YTELLIKEIR G

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of Thermus thermophilus HB8." Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S. Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HB8 / ATCC 27634 / DSM 579.
[2]	"Identification of the 50S ribosomal proteins from the eubacterium Thermus thermophilus." Katsani K.R., Tsiboli P., Anagnostopoulos K., Urlaub H., Choli-Papadopoulou T. Biol. Chem. 381:1079-1087(2000) [PubMed: 11154066] [Abstract] Cited for: PROTEIN SEQUENCE OF 1-18.
[3]	"Extending ribosomal protein identifications to unsequenced bacterial strains using matrix-assisted laser desorption/ionization mass spectrometry." Suh M.-J., Hamburg D.M., Gregory S.T., Dahlberg A.E., Limbach P.A. Proteomics 5:4818-4831(2005) [PubMed: 16287167] [Abstract] Cited for: MASS SPECTROMETRY.
[4]	"Crystal structure of the ribosome at 5.5 A resolution." Yusupov M.M., Yusupova G.Z., Baucom A., Lieberman K., Earnest T.N., Cate J.H.D., Noller H.F. Science 292:883-896(2001) [PubMed: 11283358] [Abstract] Cited for: STRUCTURE OF THE RIBOSOME.
[5]	"Translational operator of mRNA on the ribosome: how repressor proteins exclude ribosome binding." Jenner L., Romby P., Rees B., Schulze-Briese C., Springer M., Ehresmann C., Ehresmann B., Moras D., Yusupova G., Yusupov M. Science 308:120-123(2005) [PubMed: 15802605] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (5.5 ANGSTROMS) OF THE RIBOSOME.
[6]	"Structure of the 70S ribosome complexed with mRNA and tRNA." Selmer M., Dunham C.M., Murphy F.V. IV, Weixlbaumer A., Petry S., Kelley A.C., Weir J.R., Ramakrishnan V. Science 313:1935-1942(2006) [PubMed: 16959973] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 1-101 OF THE RIBOSOME.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AP008226 Genomic DNA. Translation: BAD71606.1.

RefSeq

YP_145049.1. NC_006461.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1YL3	X-ray	5.50	2	1-89	[»]
2HGJ	X-ray	5.00	U	1-101	[»]
2HGQ	X-ray	5.50	U	1-101	[»]
2HGU	X-ray	4.51	U	1-101	[»]
2J01	X-ray	2.80	V	1-101	[»]
2J03	X-ray	2.80	V	1-101	[»]
2V47	X-ray	3.80	V	1-101	[»]
2V49	X-ray	3.80	V	1-101	[»]
2WDI	X-ray	3.30	V	1-101	[»]
2WDJ	X-ray	3.30	V	1-101	[»]
2WDL	X-ray	3.50	V	1-101	[»]
2WDN	X-ray	3.50	V	1-101	[»]
2WH2	X-ray	3.45	V	1-101	[»]
2WH4	X-ray	3.45	V	1-101	[»]
2WRJ	X-ray	3.60	V	1-101	[»]
2WRL	X-ray	3.60	V	1-101	[»]
2WRO	X-ray	3.60	V	1-101	[»]
2WRR	X-ray	3.60	V	1-101	[»]
2X9S	X-ray	3.10	V	1-101	[»]
2X9U	X-ray	3.10	V	1-101	[»]
2XG0	X-ray	3.20	V	1-101	[»]
2XG2	X-ray	3.20	V	1-101	[»]
2XQE	X-ray	3.10	V	1-101	[»]
2XTG	electron microscopy	7.80	V	1-101	[»]
2XUX	electron microscopy	7.60	V	1-101	[»]
2Y0V	X-ray	3.10	V	1-101	[»]
2Y0X	X-ray	3.10	V	1-101	[»]
2Y0Z	X-ray	3.10	V	1-101	[»]
2Y11	X-ray	3.10	V	1-101	[»]
2Y13	X-ray	3.10	V	1-101	[»]
2Y15	X-ray	3.10	V	1-101	[»]
2Y17	X-ray	3.10	V	1-101	[»]
2Y19	X-ray	3.10	V	1-101	[»]
3FIN	electron microscopy	6.40	V	1-101	[»]
3HUX	X-ray	3.10	V	1-101	[»]
3HUZ	X-ray	3.10	V	1-101	[»]
3I8F	X-ray	3.10	2	1-101	[»]
3I8I	X-ray	3.10	2	1-101	[»]
3I9C	X-ray	3.50	2	1-101	[»]
3I9E	X-ray	3.50	2	1-101	[»]
3KIR	X-ray	3.30	V	1-101	[»]
3KIT	X-ray	3.30	V	1-101	[»]
3KIW	X-ray	3.60	V	1-101	[»]
3KIY	X-ray	3.60	V	1-101	[»]
3KNI	X-ray	3.00	V	1-101	[»]
3KNK	X-ray	3.00	V	1-101	[»]
3KNM	X-ray	3.45	V	1-101	[»]
3KNO	X-ray	3.45	V	1-101	[»]
3ZVP	X-ray	3.80	V	1-101	[»]

ProteinModelPortal

P60492.

SMR

P60492. Positions 1-101.

ModBase

Search...

Protein-protein interaction databases

STRING

P60492.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

3169471.

GenomeReviews

Gene locus TTHA1783 in contig AP008226_GR.

KEGG

ttj:TTHA1783.

PATRIC

23958527. VBITheThe93045_1753.

Phylogenomic databases

eggNOG

COG0261.

HOGENOM

HBG706775.

OMA

IKVEQIA.

ProtClustDB

PRK05573.

Enzyme and pathway databases

BioCyc

TTHE300852:TTHA1783-MONOMER.

Family and domain databases

HAMAP

MF_01363. Ribosomal_L21.
[Tree]

InterPro

IPR001787. Ribosomal_L21.
[Graphical view]

K02888.

PANTHER

PTHR21349. Ribosomal_L21p. 1 hit.

Pfam

PF00829. Ribosomal_L21p. 1 hit.
[Graphical view]

TIGRFAMs

TIGR00061. L21. 1 hit.

PROSITE

PS01169. RIBOSOMAL_L21. False negative.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

RL21_THET8

Accession

Primary (citable) accession number: P60492
Secondary accession number(s): Q5SHE7

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 2004
Last sequence update:	March 29, 2005
Last modified:	January 25, 2012
This is version 63 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Secondary structure

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry information

Relevant documents