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Protein

50S ribosomal protein L19

Gene

rplS

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Contacts the 16S rRNA of the 30S subunit (part of bridge B6), connecting the 2 subunits.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L19
Gene namesi
Name:rplS
Ordered Locus Names:TTHA1031
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000532 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001635581 – 14650S ribosomal protein L19Add BLAST146

Interactioni

Subunit structurei

Part of the 50S risobomal subunit. Contacts protein L14. Forms a bridge to the 30S subunit in the 70S ribosome, contacting the 16S rRNA.

Protein-protein interaction databases

STRINGi300852.TTHA1031.

Structurei

Secondary structure

1146
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi4 – 11Combined sources8
Beta strandi48 – 53Combined sources6
Beta strandi56 – 58Combined sources3
Beta strandi60 – 67Combined sources8
Beta strandi70 – 76Combined sources7
Beta strandi78 – 81Combined sources4
Beta strandi95 – 97Combined sources3
Helixi100 – 105Combined sources6
Helixi109 – 113Combined sources5
Helixi118 – 125Combined sources8
Helixi126 – 128Combined sources3
Turni134 – 136Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1VVJX-ray3.44RT/YT1-146[»]
1VY4X-ray2.60BT/DT1-146[»]
1VY5X-ray2.55BT/DT1-146[»]
1VY6X-ray2.90BT/DT1-146[»]
1VY7X-ray2.80BT/DT1-146[»]
4L47X-ray3.22RT/YT1-146[»]
4L71X-ray3.90RT/YT1-146[»]
4LELX-ray3.90RT/YT1-146[»]
4LFZX-ray3.92RT/YT1-146[»]
4LNTX-ray2.94RT/YT1-146[»]
4LSKX-ray3.48RT/YT1-146[»]
4LT8X-ray3.14RT/YT1-146[»]
4P6FX-ray3.60RT/YT1-146[»]
4P70X-ray3.68RT/YT1-146[»]
4TUAX-ray3.60RT/YT1-146[»]
4TUBX-ray3.60RT/YT1-146[»]
4TUCX-ray3.60RT/YT1-146[»]
4TUDX-ray3.60RT/YT1-146[»]
4TUEX-ray3.50RT/YT1-146[»]
4V42X-ray5.50R1-146[»]
4V4PX-ray5.50R1-146[»]
4V4XX-ray5.00BS1-146[»]
4V4YX-ray5.50BS1-146[»]
4V4ZX-ray4.51BS1-146[»]
4V51X-ray2.80BT/DT1-146[»]
4V5AX-ray3.50BT/DT1-146[»]
4V5CX-ray3.30BT/DT1-146[»]
4V5DX-ray3.50BT/DT1-146[»]
4V5EX-ray3.45BT/DT1-146[»]
4V5FX-ray3.60BT/DT1-146[»]
4V5GX-ray3.60BT/DT1-146[»]
4V5JX-ray3.10BT/DT1-146[»]
4V5KX-ray3.20BT/DT1-146[»]
4V5LX-ray3.10BT1-146[»]
4V5Melectron microscopy7.80BT1-146[»]
4V5Nelectron microscopy7.60BT1-146[»]
4V5PX-ray3.10BT/DT1-146[»]
4V5QX-ray3.10BT/DT1-146[»]
4V5RX-ray3.10BT/DT1-146[»]
4V5SX-ray3.10BT/DT1-146[»]
4V68electron microscopy6.40BT1-138[»]
4V6AX-ray3.10BT/DT1-146[»]
4V6FX-ray3.10AR/DR1-146[»]
4V6GX-ray3.50BR/DR1-146[»]
4V7JX-ray3.30AT/BT1-146[»]
4V7KX-ray3.60AT/BT1-146[»]
4V7LX-ray3.00BT/DT1-146[»]
4V7MX-ray3.45BT/DT1-146[»]
4V7WX-ray3.00BT/DT1-146[»]
4V7XX-ray3.00BT/DT1-146[»]
4V7YX-ray3.00BT/DT1-146[»]
4V7ZX-ray3.10BT/DT1-146[»]
4V87X-ray3.10AR/DR1-137[»]
4V8AX-ray3.20AT/BT1-146[»]
4V8BX-ray3.00BR/DR1-146[»]
4V8CX-ray3.30AR/BR1-146[»]
4V8DX-ray3.00BR/DR1-146[»]
4V8EX-ray3.30AR/CR1-146[»]
4V8FX-ray3.30AR/DR1-146[»]
4V8GX-ray3.00BT/DT1-146[»]
4V8HX-ray3.10BT/DT1-146[»]
4V8IX-ray2.70BT/DT1-146[»]
4V8JX-ray3.90BT/DT1-146[»]
4V8NX-ray3.10BT/DT1-146[»]
4V8OX-ray3.80BT1-146[»]
4V8QX-ray3.10AT1-146[»]
4V8UX-ray3.70BT/DT1-146[»]
4V8XX-ray3.35BT/DT1-146[»]
4V90X-ray2.95BT1-146[»]
4V95X-ray3.20BT/DT1-146[»]
4V97X-ray3.52BT/DT1-146[»]
4V9AX-ray3.30BR/DR1-146[»]
4V9BX-ray3.10BR/DR1-146[»]
4V9HX-ray2.86BT1-146[»]
4V9IX-ray3.30BT/DT1-137[»]
4V9RX-ray3.00BT/DT1-146[»]
4V9SX-ray3.10BT/DT1-146[»]
4W2EX-ray2.90T1-146[»]
4W2FX-ray2.40BT/DT1-146[»]
4W2GX-ray2.55BT/DT1-146[»]
4W2HX-ray2.70BT/DT1-146[»]
4W2IX-ray2.70BT/DT1-146[»]
4W4GX-ray3.30RT/YT1-146[»]
4WPOX-ray2.80AT/CT1-146[»]
4WQ1X-ray3.1075/B81-137[»]
4WQFX-ray2.80AT/CT1-146[»]
4WQRX-ray3.1575/B81-146[»]
4WQUX-ray2.80AT/CT1-146[»]
4WQYX-ray2.80AT/CT1-146[»]
4WR6X-ray3.0575/B81-146[»]
4WRAX-ray3.0575/B81-146[»]
4WROX-ray3.05B81-146[»]
4WSDX-ray2.9575/B81-146[»]
4WSMX-ray3.3075/B81-146[»]
4WT1X-ray3.0575/B81-146[»]
4WT8X-ray3.40CS/DS1-137[»]
4WU1X-ray3.2075/B81-146[»]
4WZDX-ray3.1075/B81-146[»]
4WZOX-ray3.3075/B81-146[»]
4Y4OX-ray2.301T/2T1-146[»]
4Y4PX-ray2.501T/2T1-146[»]
4YPBX-ray3.40RT/YT1-146[»]
4YZVX-ray3.10RT/YT1-146[»]
4Z3SX-ray2.651T/2T1-146[»]
4Z8CX-ray2.901T/2T1-146[»]
4ZERX-ray3.101T/2T1-131[»]
4ZSNX-ray3.60RT/YT1-146[»]
5A9Zelectron microscopy4.70AQ1-117[»]
5AA0electron microscopy5.00AQ1-117[»]
5CZPX-ray3.30RT/YT1-146[»]
5D8BX-ray3.63JB/N1-146[»]
5DFEX-ray3.10RT/YT1-146[»]
5DOXX-ray3.101T/2T1-146[»]
5DOYX-ray2.601T/2T1-146[»]
5E7KX-ray3.2075/B81-146[»]
5E81X-ray2.9575/B81-146[»]
5EL4X-ray3.1575/B81-146[»]
5EL5X-ray3.1575/B81-146[»]
5EL6X-ray3.1075/B81-146[»]
5EL7X-ray3.1575/B81-146[»]
5F8KX-ray2.801T/2T1-131[»]
5FDUX-ray2.901T/2T1-131[»]
5FDVX-ray2.801T/2T1-131[»]
5HAUX-ray3.001R/2R1-146[»]
5HCPX-ray2.891T/2T1-146[»]
5HCQX-ray2.801T/2T1-146[»]
5HCRX-ray2.801T/2T1-146[»]
5HD1X-ray2.701T/2T1-146[»]
5IB7X-ray2.9975/B81-146[»]
5IB8X-ray3.1375/B81-146[»]
5IBBX-ray2.9675/B81-146[»]
5IMQelectron microscopy3.80l1-146[»]
5IMRelectron microscopy-l1-146[»]
5J30X-ray3.20RT/YT1-146[»]
5J3CX-ray3.04RT/YT1-146[»]
5J4BX-ray2.601T/2T1-146[»]
5J4CX-ray2.801T/2T1-146[»]
5J8BX-ray2.60T1-146[»]
ProteinModelPortaliP60490.
SMRiP60490.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP60490.

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L19P family.Curated

Phylogenomic databases

eggNOGiENOG4108YY1. Bacteria.
COG0335. LUCA.
HOGENOMiHOG000016265.
KOiK02884.
OMAiSPMIESV.
PhylomeDBiP60490.

Family and domain databases

HAMAPiMF_00402. Ribosomal_L19. 1 hit.
InterProiIPR001857. Ribosomal_L19.
IPR018257. Ribosomal_L19_CS.
IPR008991. Translation_prot_SH3-like.
[Graphical view]
PANTHERiPTHR15680. PTHR15680. 1 hit.
PfamiPF01245. Ribosomal_L19. 1 hit.
[Graphical view]
PIRSFiPIRSF002191. Ribosomal_L19. 1 hit.
PRINTSiPR00061. RIBOSOMALL19.
SUPFAMiSSF50104. SSF50104. 1 hit.
TIGRFAMsiTIGR01024. rplS_bact. 1 hit.
PROSITEiPS01015. RIBOSOMAL_L19. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P60490-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNRGALIKLV ESRYVRTDLP EFRPGDTVRV SYKVKEGNRT RIQDFEGIVI
60 70 80 90 100
RIRRNGFNTT FTVRKVSYGV GVERIFPLHS PLIQKIDIVQ RGRARRAKLY
110 120 130 140
FIRNLSDREI RRKLRADRKR IDQDRAAERA AKEEAQKAQE PKASQE
Length:146
Mass (Da):17,152
Last modified:March 29, 2005 - v2
Checksum:i119CC349889AF6A7
GO

Mass spectrometryi

Molecular mass is 17152 Da from positions 1 - 146. Determined by MALDI. 1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008226 Genomic DNA. Translation: BAD70854.1.
RefSeqiWP_011228391.1. NC_006461.1.
YP_144297.1. NC_006461.1.

Genome annotation databases

EnsemblBacteriaiBAD70854; BAD70854; BAD70854.
GeneIDi3168297.
KEGGittj:TTHA1031.
PATRICi23957022. VBITheThe93045_1011.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008226 Genomic DNA. Translation: BAD70854.1.
RefSeqiWP_011228391.1. NC_006461.1.
YP_144297.1. NC_006461.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1VVJX-ray3.44RT/YT1-146[»]
1VY4X-ray2.60BT/DT1-146[»]
1VY5X-ray2.55BT/DT1-146[»]
1VY6X-ray2.90BT/DT1-146[»]
1VY7X-ray2.80BT/DT1-146[»]
4L47X-ray3.22RT/YT1-146[»]
4L71X-ray3.90RT/YT1-146[»]
4LELX-ray3.90RT/YT1-146[»]
4LFZX-ray3.92RT/YT1-146[»]
4LNTX-ray2.94RT/YT1-146[»]
4LSKX-ray3.48RT/YT1-146[»]
4LT8X-ray3.14RT/YT1-146[»]
4P6FX-ray3.60RT/YT1-146[»]
4P70X-ray3.68RT/YT1-146[»]
4TUAX-ray3.60RT/YT1-146[»]
4TUBX-ray3.60RT/YT1-146[»]
4TUCX-ray3.60RT/YT1-146[»]
4TUDX-ray3.60RT/YT1-146[»]
4TUEX-ray3.50RT/YT1-146[»]
4V42X-ray5.50R1-146[»]
4V4PX-ray5.50R1-146[»]
4V4XX-ray5.00BS1-146[»]
4V4YX-ray5.50BS1-146[»]
4V4ZX-ray4.51BS1-146[»]
4V51X-ray2.80BT/DT1-146[»]
4V5AX-ray3.50BT/DT1-146[»]
4V5CX-ray3.30BT/DT1-146[»]
4V5DX-ray3.50BT/DT1-146[»]
4V5EX-ray3.45BT/DT1-146[»]
4V5FX-ray3.60BT/DT1-146[»]
4V5GX-ray3.60BT/DT1-146[»]
4V5JX-ray3.10BT/DT1-146[»]
4V5KX-ray3.20BT/DT1-146[»]
4V5LX-ray3.10BT1-146[»]
4V5Melectron microscopy7.80BT1-146[»]
4V5Nelectron microscopy7.60BT1-146[»]
4V5PX-ray3.10BT/DT1-146[»]
4V5QX-ray3.10BT/DT1-146[»]
4V5RX-ray3.10BT/DT1-146[»]
4V5SX-ray3.10BT/DT1-146[»]
4V68electron microscopy6.40BT1-138[»]
4V6AX-ray3.10BT/DT1-146[»]
4V6FX-ray3.10AR/DR1-146[»]
4V6GX-ray3.50BR/DR1-146[»]
4V7JX-ray3.30AT/BT1-146[»]
4V7KX-ray3.60AT/BT1-146[»]
4V7LX-ray3.00BT/DT1-146[»]
4V7MX-ray3.45BT/DT1-146[»]
4V7WX-ray3.00BT/DT1-146[»]
4V7XX-ray3.00BT/DT1-146[»]
4V7YX-ray3.00BT/DT1-146[»]
4V7ZX-ray3.10BT/DT1-146[»]
4V87X-ray3.10AR/DR1-137[»]
4V8AX-ray3.20AT/BT1-146[»]
4V8BX-ray3.00BR/DR1-146[»]
4V8CX-ray3.30AR/BR1-146[»]
4V8DX-ray3.00BR/DR1-146[»]
4V8EX-ray3.30AR/CR1-146[»]
4V8FX-ray3.30AR/DR1-146[»]
4V8GX-ray3.00BT/DT1-146[»]
4V8HX-ray3.10BT/DT1-146[»]
4V8IX-ray2.70BT/DT1-146[»]
4V8JX-ray3.90BT/DT1-146[»]
4V8NX-ray3.10BT/DT1-146[»]
4V8OX-ray3.80BT1-146[»]
4V8QX-ray3.10AT1-146[»]
4V8UX-ray3.70BT/DT1-146[»]
4V8XX-ray3.35BT/DT1-146[»]
4V90X-ray2.95BT1-146[»]
4V95X-ray3.20BT/DT1-146[»]
4V97X-ray3.52BT/DT1-146[»]
4V9AX-ray3.30BR/DR1-146[»]
4V9BX-ray3.10BR/DR1-146[»]
4V9HX-ray2.86BT1-146[»]
4V9IX-ray3.30BT/DT1-137[»]
4V9RX-ray3.00BT/DT1-146[»]
4V9SX-ray3.10BT/DT1-146[»]
4W2EX-ray2.90T1-146[»]
4W2FX-ray2.40BT/DT1-146[»]
4W2GX-ray2.55BT/DT1-146[»]
4W2HX-ray2.70BT/DT1-146[»]
4W2IX-ray2.70BT/DT1-146[»]
4W4GX-ray3.30RT/YT1-146[»]
4WPOX-ray2.80AT/CT1-146[»]
4WQ1X-ray3.1075/B81-137[»]
4WQFX-ray2.80AT/CT1-146[»]
4WQRX-ray3.1575/B81-146[»]
4WQUX-ray2.80AT/CT1-146[»]
4WQYX-ray2.80AT/CT1-146[»]
4WR6X-ray3.0575/B81-146[»]
4WRAX-ray3.0575/B81-146[»]
4WROX-ray3.05B81-146[»]
4WSDX-ray2.9575/B81-146[»]
4WSMX-ray3.3075/B81-146[»]
4WT1X-ray3.0575/B81-146[»]
4WT8X-ray3.40CS/DS1-137[»]
4WU1X-ray3.2075/B81-146[»]
4WZDX-ray3.1075/B81-146[»]
4WZOX-ray3.3075/B81-146[»]
4Y4OX-ray2.301T/2T1-146[»]
4Y4PX-ray2.501T/2T1-146[»]
4YPBX-ray3.40RT/YT1-146[»]
4YZVX-ray3.10RT/YT1-146[»]
4Z3SX-ray2.651T/2T1-146[»]
4Z8CX-ray2.901T/2T1-146[»]
4ZERX-ray3.101T/2T1-131[»]
4ZSNX-ray3.60RT/YT1-146[»]
5A9Zelectron microscopy4.70AQ1-117[»]
5AA0electron microscopy5.00AQ1-117[»]
5CZPX-ray3.30RT/YT1-146[»]
5D8BX-ray3.63JB/N1-146[»]
5DFEX-ray3.10RT/YT1-146[»]
5DOXX-ray3.101T/2T1-146[»]
5DOYX-ray2.601T/2T1-146[»]
5E7KX-ray3.2075/B81-146[»]
5E81X-ray2.9575/B81-146[»]
5EL4X-ray3.1575/B81-146[»]
5EL5X-ray3.1575/B81-146[»]
5EL6X-ray3.1075/B81-146[»]
5EL7X-ray3.1575/B81-146[»]
5F8KX-ray2.801T/2T1-131[»]
5FDUX-ray2.901T/2T1-131[»]
5FDVX-ray2.801T/2T1-131[»]
5HAUX-ray3.001R/2R1-146[»]
5HCPX-ray2.891T/2T1-146[»]
5HCQX-ray2.801T/2T1-146[»]
5HCRX-ray2.801T/2T1-146[»]
5HD1X-ray2.701T/2T1-146[»]
5IB7X-ray2.9975/B81-146[»]
5IB8X-ray3.1375/B81-146[»]
5IBBX-ray2.9675/B81-146[»]
5IMQelectron microscopy3.80l1-146[»]
5IMRelectron microscopy-l1-146[»]
5J30X-ray3.20RT/YT1-146[»]
5J3CX-ray3.04RT/YT1-146[»]
5J4BX-ray2.601T/2T1-146[»]
5J4CX-ray2.801T/2T1-146[»]
5J8BX-ray2.60T1-146[»]
ProteinModelPortaliP60490.
SMRiP60490.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi300852.TTHA1031.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD70854; BAD70854; BAD70854.
GeneIDi3168297.
KEGGittj:TTHA1031.
PATRICi23957022. VBITheThe93045_1011.

Phylogenomic databases

eggNOGiENOG4108YY1. Bacteria.
COG0335. LUCA.
HOGENOMiHOG000016265.
KOiK02884.
OMAiSPMIESV.
PhylomeDBiP60490.

Miscellaneous databases

EvolutionaryTraceiP60490.

Family and domain databases

HAMAPiMF_00402. Ribosomal_L19. 1 hit.
InterProiIPR001857. Ribosomal_L19.
IPR018257. Ribosomal_L19_CS.
IPR008991. Translation_prot_SH3-like.
[Graphical view]
PANTHERiPTHR15680. PTHR15680. 1 hit.
PfamiPF01245. Ribosomal_L19. 1 hit.
[Graphical view]
PIRSFiPIRSF002191. Ribosomal_L19. 1 hit.
PRINTSiPR00061. RIBOSOMALL19.
SUPFAMiSSF50104. SSF50104. 1 hit.
TIGRFAMsiTIGR01024. rplS_bact. 1 hit.
PROSITEiPS01015. RIBOSOMAL_L19. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRL19_THET8
AccessioniPrimary (citable) accession number: P60490
Secondary accession number(s): Q5SJH7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 2004
Last sequence update: March 29, 2005
Last modified: November 30, 2016
This is version 115 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.