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P60490 (RL19_THET8) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
50S ribosomal protein L19
Gene names
Name:rplS
Ordered Locus Names:TTHA1031
OrganismThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) [Reference proteome] [HAMAP]
Taxonomic identifier300852 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

Protein attributes

Sequence length146 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Contacts the 16S rRNA of the 30S subunit (part of bridge B6), connecting the 2 subunits. HAMAP-Rule MF_00402

Subunit structure

Part of the 50S risobomal subunit. Contacts protein L14. Forms a bridge to the 30S subunit in the 70S ribosome, contacting the 16S rRNA. Ref.5

Sequence similarities

Belongs to the ribosomal protein L19P family.

Mass spectrometry

Molecular mass is 17152 Da from positions 1 - 146. Determined by MALDI. Ref.3

Ontologies

Keywords
   LigandRNA-binding
rRNA-binding
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical term3D-structure
Complete proteome
Direct protein sequencing
Reference proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentribosome

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionrRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

structural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 14614650S ribosomal protein L19 HAMAP-Rule MF_00402
PRO_0000163558

Secondary structure

................................ 146
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P60490 [UniParc].

Last modified March 29, 2005. Version 2.
Checksum: 119CC349889AF6A7

FASTA14617,152
        10         20         30         40         50         60 
MNRGALIKLV ESRYVRTDLP EFRPGDTVRV SYKVKEGNRT RIQDFEGIVI RIRRNGFNTT 

        70         80         90        100        110        120 
FTVRKVSYGV GVERIFPLHS PLIQKIDIVQ RGRARRAKLY FIRNLSDREI RRKLRADRKR 

       130        140 
IDQDRAAERA AKEEAQKAQE PKASQE 

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of Thermus thermophilus HB8."
Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HB8 / ATCC 27634 / DSM 579.
[2]"Identification of the 50S ribosomal proteins from the eubacterium Thermus thermophilus."
Katsani K.R., Tsiboli P., Anagnostopoulos K., Urlaub H., Choli-Papadopoulou T.
Biol. Chem. 381:1079-1087(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 1-29.
[3]"Extending ribosomal protein identifications to unsequenced bacterial strains using matrix-assisted laser desorption/ionization mass spectrometry."
Suh M.-J., Hamburg D.M., Gregory S.T., Dahlberg A.E., Limbach P.A.
Proteomics 5:4818-4831(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: MASS SPECTROMETRY.
[4]"The path of messenger RNA through the ribosome."
Yusupova G.Z., Yusupov M.M., Cate J.H.D., Noller H.F.
Cell 106:233-241(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (5.0 ANGSTROMS) OF THE RIBOSOME.
[5]"Crystal structure of the ribosome at 5.5 A resolution."
Yusupov M.M., Yusupova G.Z., Baucom A., Lieberman K., Earnest T.N., Cate J.H.D., Noller H.F.
Science 292:883-896(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (5.5 ANGSTROMS) OF THE RIBOSOME, INTERSUBUNIT BRIDGE FORMATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008226 Genomic DNA. Translation: BAD70854.1.
RefSeqYP_144297.1. NC_006461.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1GIYX-ray5.50R1-146[»]
1YL3X-ray5.50R1-146[»]
2HGJX-ray5.00S1-146[»]
2HGQX-ray5.50S1-146[»]
2HGUX-ray4.51S1-146[»]
2J01X-ray2.80T1-146[»]
2J03X-ray2.80T1-146[»]
2V47X-ray3.80T1-146[»]
2V49X-ray3.80T1-146[»]
2WDIX-ray3.30T1-146[»]
2WDJX-ray3.30T1-146[»]
2WDLX-ray3.50T1-146[»]
2WDNX-ray3.50T1-146[»]
2WH2X-ray3.45T1-146[»]
2WH4X-ray3.45T1-146[»]
2WRJX-ray3.60T1-146[»]
2WRLX-ray3.60T1-146[»]
2WROX-ray3.60T1-146[»]
2WRRX-ray3.60T1-146[»]
2X9SX-ray3.10T1-146[»]
2X9UX-ray3.10T1-146[»]
2XG0X-ray3.20T1-146[»]
2XG2X-ray3.20T1-146[»]
2XQEX-ray3.10T1-146[»]
2XTGelectron microscopy7.80T1-146[»]
2XUXelectron microscopy7.60T1-146[»]
2Y0VX-ray3.10T1-146[»]
2Y0XX-ray3.10T1-146[»]
2Y0ZX-ray3.10T1-146[»]
2Y11X-ray3.10T1-146[»]
2Y13X-ray3.10T1-146[»]
2Y15X-ray3.10T1-146[»]
2Y17X-ray3.10T1-146[»]
2Y19X-ray3.10T1-146[»]
3FINelectron microscopy6.40T1-138[»]
3HUXX-ray3.10T1-146[»]
3HUZX-ray3.10T1-146[»]
3I8FX-ray3.10R1-146[»]
3I8IX-ray3.10R1-146[»]
3I9CX-ray3.50R1-146[»]
3I9EX-ray3.50R1-146[»]
3KIRX-ray3.30T1-146[»]
3KITX-ray3.30T1-146[»]
3KIWX-ray3.60T1-146[»]
3KIYX-ray3.60T1-146[»]
3KNIX-ray3.00T1-146[»]
3KNKX-ray3.00T1-146[»]
3KNMX-ray3.45T1-146[»]
3KNOX-ray3.45T1-146[»]
3TVEX-ray3.10R1-137[»]
3TVHX-ray3.10R1-137[»]
3UXQX-ray3.20T1-146[»]
3UXRX-ray3.20T1-146[»]
3UYEX-ray3.00R1-146[»]
3UYGX-ray3.00R1-146[»]
3UZ1X-ray3.30R1-146[»]
3UZ2X-ray3.30R1-146[»]
3UZ8X-ray3.00R1-146[»]
3UZ9X-ray3.00R1-146[»]
3UZFX-ray3.30R1-146[»]
3UZHX-ray3.30R1-146[»]
3UZKX-ray3.30R1-146[»]
3UZNX-ray3.30R1-146[»]
3V23X-ray3.00T1-146[»]
3V25X-ray3.00T1-146[»]
3V27X-ray3.10T1-146[»]
3V29X-ray3.10T1-146[»]
3V2DX-ray2.70T1-146[»]
3V2FX-ray2.70T1-146[»]
3V6WX-ray3.90T1-146[»]
3V6XX-ray3.90T1-146[»]
3ZN9X-ray3.10T1-146[»]
3ZNEX-ray3.10T1-146[»]
3ZVPX-ray3.80T1-146[»]
4ABSX-ray3.10T1-146[»]
4B8GX-ray3.70T1-146[»]
4B8IX-ray3.70T1-146[»]
4BTDX-ray2.95T1-146[»]
4BYCX-ray3.35T1-146[»]
4BYEX-ray3.35T1-146[»]
4DHAX-ray3.20T1-146[»]
4DHCX-ray3.20T1-146[»]
4EJBX-ray3.52T1-146[»]
4EJCX-ray3.52T1-146[»]
4G5LX-ray3.30R1-146[»]
4G5NX-ray3.30R1-146[»]
4G5UX-ray3.10R1-146[»]
4G5WX-ray3.10R1-146[»]
4JUXX-ray2.86T1-146[»]
4K0MX-ray3.30T1-137[»]
4K0QX-ray3.30T1-137[»]
ProteinModelPortalP60490.
SMRP60490. Positions 1-137.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING300852.TTHA1031.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAD70854; BAD70854; BAD70854.
GeneID3168297.
KEGGttj:TTHA1031.
PATRIC23957022. VBITheThe93045_1011.

Phylogenomic databases

eggNOGCOG0335.
HOGENOMHOG000016265.
KOK02884.
OMALVESRYV.
OrthoDBEOG6DZF5W.
ProtClustDBPRK05338.

Enzyme and pathway databases

BioCycTTHE300852:GH8R-1063-MONOMER.

Family and domain databases

HAMAPMF_00402. Ribosomal_L19.
InterProIPR001857. Ribosomal_L19.
IPR018257. Ribosomal_L19_CS.
IPR008991. Translation_prot_SH3-like.
[Graphical view]
PANTHERPTHR15680. PTHR15680. 1 hit.
PfamPF01245. Ribosomal_L19. 1 hit.
[Graphical view]
PIRSFPIRSF002191. Ribosomal_L19. 1 hit.
PRINTSPR00061. RIBOSOMALL19.
SUPFAMSSF50104. SSF50104. 1 hit.
TIGRFAMsTIGR01024. rplS_bact. 1 hit.
PROSITEPS01015. RIBOSOMAL_L19. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP60490.

Entry information

Entry nameRL19_THET8
AccessionPrimary (citable) accession number: P60490
Secondary accession number(s): Q5SJH7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 2004
Last sequence update: March 29, 2005
Last modified: February 19, 2014
This is version 89 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references