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P60490

- RL19_THET8

UniProt

P60490 - RL19_THET8

Protein

50S ribosomal protein L19

Gene

rplS

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 93 (01 Oct 2014)
      Sequence version 2 (29 Mar 2005)
      Previous versions | rss
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    Functioni

    Contacts the 16S rRNA of the 30S subunit (part of bridge B6), connecting the 2 subunits.

    GO - Molecular functioni

    1. rRNA binding Source: UniProtKB-KW
    2. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding

    Enzyme and pathway databases

    BioCyciTTHE300852:GH8R-1063-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    50S ribosomal protein L19
    Gene namesi
    Name:rplS
    Ordered Locus Names:TTHA1031
    OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
    Taxonomic identifieri300852 [NCBI]
    Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
    ProteomesiUP000000532: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. ribosome Source: UniProtKB-KW

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 14614650S ribosomal protein L19PRO_0000163558Add
    BLAST

    Interactioni

    Subunit structurei

    Part of the 50S risobomal subunit. Contacts protein L14. Forms a bridge to the 30S subunit in the 70S ribosome, contacting the 16S rRNA.

    Protein-protein interaction databases

    STRINGi300852.TTHA1031.

    Structurei

    Secondary structure

    1
    146
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi3 – 1210
    Beta strandi17 – 193
    Beta strandi23 – 253
    Beta strandi27 – 359
    Beta strandi36 – 394
    Beta strandi40 – 5314
    Helixi56 – 583
    Beta strandi60 – 678
    Beta strandi70 – 778
    Beta strandi78 – 814
    Beta strandi83 – 908
    Beta strandi95 – 973
    Helixi100 – 1045
    Helixi107 – 1137
    Beta strandi114 – 1163
    Helixi118 – 1258
    Turni130 – 1334
    Turni134 – 1363

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1GIYX-ray5.50R1-146[»]
    1YL3X-ray5.50R1-146[»]
    2HGJX-ray5.00S1-146[»]
    2HGQX-ray5.50S1-146[»]
    2HGUX-ray4.51S1-146[»]
    2J01X-ray2.80T1-146[»]
    2J03X-ray2.80T1-146[»]
    2V47X-ray3.80T1-146[»]
    2V49X-ray3.80T1-146[»]
    2WDIX-ray3.30T1-146[»]
    2WDJX-ray3.30T1-146[»]
    2WDLX-ray3.50T1-146[»]
    2WDNX-ray3.50T1-146[»]
    2WH2X-ray3.45T1-146[»]
    2WH4X-ray3.45T1-146[»]
    2WRJX-ray3.60T1-146[»]
    2WRLX-ray3.60T1-146[»]
    2WROX-ray3.60T1-146[»]
    2WRRX-ray3.60T1-146[»]
    2X9SX-ray3.10T1-146[»]
    2X9UX-ray3.10T1-146[»]
    2XG0X-ray3.20T1-146[»]
    2XG2X-ray3.20T1-146[»]
    2XQEX-ray3.10T1-146[»]
    2XTGelectron microscopy7.80T1-146[»]
    2XUXelectron microscopy7.60T1-146[»]
    2Y0VX-ray3.10T1-146[»]
    2Y0XX-ray3.10T1-146[»]
    2Y0ZX-ray3.10T1-146[»]
    2Y11X-ray3.10T1-146[»]
    2Y13X-ray3.10T1-146[»]
    2Y15X-ray3.10T1-146[»]
    2Y17X-ray3.10T1-146[»]
    2Y19X-ray3.10T1-146[»]
    3FINelectron microscopy6.40T1-138[»]
    3HUXX-ray3.10T1-146[»]
    3HUZX-ray3.10T1-146[»]
    3I8FX-ray3.10R1-146[»]
    3I8IX-ray3.10R1-146[»]
    3I9CX-ray3.50R1-146[»]
    3I9EX-ray3.50R1-146[»]
    3KIRX-ray3.30T1-146[»]
    3KITX-ray3.30T1-146[»]
    3KIWX-ray3.60T1-146[»]
    3KIYX-ray3.60T1-146[»]
    3KNIX-ray3.00T1-146[»]
    3KNKX-ray3.00T1-146[»]
    3KNMX-ray3.45T1-146[»]
    3KNOX-ray3.45T1-146[»]
    3OH7X-ray3.00T1-146[»]
    3OI3X-ray3.10T1-146[»]
    3OI5X-ray3.10T1-146[»]
    3TVEX-ray3.10R1-137[»]
    3TVHX-ray3.10R1-137[»]
    3UXQX-ray3.20T1-146[»]
    3UXRX-ray3.20T1-146[»]
    3UYEX-ray3.00R1-146[»]
    3UYGX-ray3.00R1-146[»]
    3UZ1X-ray3.30R1-146[»]
    3UZ2X-ray3.30R1-146[»]
    3UZ8X-ray3.00R1-146[»]
    3UZ9X-ray3.00R1-146[»]
    3UZFX-ray3.30R1-146[»]
    3UZHX-ray3.30R1-146[»]
    3UZKX-ray3.30R1-146[»]
    3UZNX-ray3.30R1-146[»]
    3V23X-ray3.00T1-146[»]
    3V25X-ray3.00T1-146[»]
    3V27X-ray3.10T1-146[»]
    3V29X-ray3.10T1-146[»]
    3V2DX-ray2.70T1-146[»]
    3V2FX-ray2.70T1-146[»]
    3V6WX-ray3.90T1-146[»]
    3V6XX-ray3.90T1-146[»]
    3ZN9X-ray3.10T1-146[»]
    3ZNEX-ray3.10T1-146[»]
    3ZVPX-ray3.80T1-146[»]
    4ABSX-ray3.10T1-146[»]
    4B8GX-ray3.70T1-146[»]
    4B8IX-ray3.70T1-146[»]
    4BTDX-ray2.95T1-146[»]
    4BYCX-ray3.35T1-146[»]
    4BYEX-ray3.35T1-146[»]
    4DHAX-ray3.20T1-146[»]
    4DHCX-ray3.20T1-146[»]
    4EJBX-ray3.52T1-146[»]
    4EJCX-ray3.52T1-146[»]
    4G5LX-ray3.30R1-146[»]
    4G5NX-ray3.30R1-146[»]
    4G5UX-ray3.10R1-146[»]
    4G5WX-ray3.10R1-146[»]
    4JUXX-ray2.86T1-146[»]
    4K0MX-ray3.30T1-137[»]
    4K0QX-ray3.30T1-137[»]
    4NVVX-ray3.00T1-146[»]
    4NVXX-ray3.00T1-146[»]
    4NVZX-ray3.10T1-146[»]
    4NW1X-ray3.10T1-146[»]
    ProteinModelPortaliP60490.
    SMRiP60490. Positions 1-137.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP60490.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L19P family.Curated

    Phylogenomic databases

    eggNOGiCOG0335.
    HOGENOMiHOG000016265.
    KOiK02884.
    OMAiKRIDQDR.
    OrthoDBiEOG6DZF5W.
    PhylomeDBiP60490.

    Family and domain databases

    HAMAPiMF_00402. Ribosomal_L19.
    InterProiIPR001857. Ribosomal_L19.
    IPR018257. Ribosomal_L19_CS.
    IPR008991. Translation_prot_SH3-like.
    [Graphical view]
    PANTHERiPTHR15680. PTHR15680. 1 hit.
    PfamiPF01245. Ribosomal_L19. 1 hit.
    [Graphical view]
    PIRSFiPIRSF002191. Ribosomal_L19. 1 hit.
    PRINTSiPR00061. RIBOSOMALL19.
    SUPFAMiSSF50104. SSF50104. 1 hit.
    TIGRFAMsiTIGR01024. rplS_bact. 1 hit.
    PROSITEiPS01015. RIBOSOMAL_L19. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P60490-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNRGALIKLV ESRYVRTDLP EFRPGDTVRV SYKVKEGNRT RIQDFEGIVI    50
    RIRRNGFNTT FTVRKVSYGV GVERIFPLHS PLIQKIDIVQ RGRARRAKLY 100
    FIRNLSDREI RRKLRADRKR IDQDRAAERA AKEEAQKAQE PKASQE 146
    Length:146
    Mass (Da):17,152
    Last modified:March 29, 2005 - v2
    Checksum:i119CC349889AF6A7
    GO

    Mass spectrometryi

    Molecular mass is 17152 Da from positions 1 - 146. Determined by MALDI. 1 Publication

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008226 Genomic DNA. Translation: BAD70854.1.
    RefSeqiYP_144297.1. NC_006461.1.

    Genome annotation databases

    EnsemblBacteriaiBAD70854; BAD70854; BAD70854.
    GeneIDi3168297.
    KEGGittj:TTHA1031.
    PATRICi23957022. VBITheThe93045_1011.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008226 Genomic DNA. Translation: BAD70854.1 .
    RefSeqi YP_144297.1. NC_006461.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1GIY X-ray 5.50 R 1-146 [» ]
    1YL3 X-ray 5.50 R 1-146 [» ]
    2HGJ X-ray 5.00 S 1-146 [» ]
    2HGQ X-ray 5.50 S 1-146 [» ]
    2HGU X-ray 4.51 S 1-146 [» ]
    2J01 X-ray 2.80 T 1-146 [» ]
    2J03 X-ray 2.80 T 1-146 [» ]
    2V47 X-ray 3.80 T 1-146 [» ]
    2V49 X-ray 3.80 T 1-146 [» ]
    2WDI X-ray 3.30 T 1-146 [» ]
    2WDJ X-ray 3.30 T 1-146 [» ]
    2WDL X-ray 3.50 T 1-146 [» ]
    2WDN X-ray 3.50 T 1-146 [» ]
    2WH2 X-ray 3.45 T 1-146 [» ]
    2WH4 X-ray 3.45 T 1-146 [» ]
    2WRJ X-ray 3.60 T 1-146 [» ]
    2WRL X-ray 3.60 T 1-146 [» ]
    2WRO X-ray 3.60 T 1-146 [» ]
    2WRR X-ray 3.60 T 1-146 [» ]
    2X9S X-ray 3.10 T 1-146 [» ]
    2X9U X-ray 3.10 T 1-146 [» ]
    2XG0 X-ray 3.20 T 1-146 [» ]
    2XG2 X-ray 3.20 T 1-146 [» ]
    2XQE X-ray 3.10 T 1-146 [» ]
    2XTG electron microscopy 7.80 T 1-146 [» ]
    2XUX electron microscopy 7.60 T 1-146 [» ]
    2Y0V X-ray 3.10 T 1-146 [» ]
    2Y0X X-ray 3.10 T 1-146 [» ]
    2Y0Z X-ray 3.10 T 1-146 [» ]
    2Y11 X-ray 3.10 T 1-146 [» ]
    2Y13 X-ray 3.10 T 1-146 [» ]
    2Y15 X-ray 3.10 T 1-146 [» ]
    2Y17 X-ray 3.10 T 1-146 [» ]
    2Y19 X-ray 3.10 T 1-146 [» ]
    3FIN electron microscopy 6.40 T 1-138 [» ]
    3HUX X-ray 3.10 T 1-146 [» ]
    3HUZ X-ray 3.10 T 1-146 [» ]
    3I8F X-ray 3.10 R 1-146 [» ]
    3I8I X-ray 3.10 R 1-146 [» ]
    3I9C X-ray 3.50 R 1-146 [» ]
    3I9E X-ray 3.50 R 1-146 [» ]
    3KIR X-ray 3.30 T 1-146 [» ]
    3KIT X-ray 3.30 T 1-146 [» ]
    3KIW X-ray 3.60 T 1-146 [» ]
    3KIY X-ray 3.60 T 1-146 [» ]
    3KNI X-ray 3.00 T 1-146 [» ]
    3KNK X-ray 3.00 T 1-146 [» ]
    3KNM X-ray 3.45 T 1-146 [» ]
    3KNO X-ray 3.45 T 1-146 [» ]
    3OH7 X-ray 3.00 T 1-146 [» ]
    3OI3 X-ray 3.10 T 1-146 [» ]
    3OI5 X-ray 3.10 T 1-146 [» ]
    3TVE X-ray 3.10 R 1-137 [» ]
    3TVH X-ray 3.10 R 1-137 [» ]
    3UXQ X-ray 3.20 T 1-146 [» ]
    3UXR X-ray 3.20 T 1-146 [» ]
    3UYE X-ray 3.00 R 1-146 [» ]
    3UYG X-ray 3.00 R 1-146 [» ]
    3UZ1 X-ray 3.30 R 1-146 [» ]
    3UZ2 X-ray 3.30 R 1-146 [» ]
    3UZ8 X-ray 3.00 R 1-146 [» ]
    3UZ9 X-ray 3.00 R 1-146 [» ]
    3UZF X-ray 3.30 R 1-146 [» ]
    3UZH X-ray 3.30 R 1-146 [» ]
    3UZK X-ray 3.30 R 1-146 [» ]
    3UZN X-ray 3.30 R 1-146 [» ]
    3V23 X-ray 3.00 T 1-146 [» ]
    3V25 X-ray 3.00 T 1-146 [» ]
    3V27 X-ray 3.10 T 1-146 [» ]
    3V29 X-ray 3.10 T 1-146 [» ]
    3V2D X-ray 2.70 T 1-146 [» ]
    3V2F X-ray 2.70 T 1-146 [» ]
    3V6W X-ray 3.90 T 1-146 [» ]
    3V6X X-ray 3.90 T 1-146 [» ]
    3ZN9 X-ray 3.10 T 1-146 [» ]
    3ZNE X-ray 3.10 T 1-146 [» ]
    3ZVP X-ray 3.80 T 1-146 [» ]
    4ABS X-ray 3.10 T 1-146 [» ]
    4B8G X-ray 3.70 T 1-146 [» ]
    4B8I X-ray 3.70 T 1-146 [» ]
    4BTD X-ray 2.95 T 1-146 [» ]
    4BYC X-ray 3.35 T 1-146 [» ]
    4BYE X-ray 3.35 T 1-146 [» ]
    4DHA X-ray 3.20 T 1-146 [» ]
    4DHC X-ray 3.20 T 1-146 [» ]
    4EJB X-ray 3.52 T 1-146 [» ]
    4EJC X-ray 3.52 T 1-146 [» ]
    4G5L X-ray 3.30 R 1-146 [» ]
    4G5N X-ray 3.30 R 1-146 [» ]
    4G5U X-ray 3.10 R 1-146 [» ]
    4G5W X-ray 3.10 R 1-146 [» ]
    4JUX X-ray 2.86 T 1-146 [» ]
    4K0M X-ray 3.30 T 1-137 [» ]
    4K0Q X-ray 3.30 T 1-137 [» ]
    4NVV X-ray 3.00 T 1-146 [» ]
    4NVX X-ray 3.00 T 1-146 [» ]
    4NVZ X-ray 3.10 T 1-146 [» ]
    4NW1 X-ray 3.10 T 1-146 [» ]
    ProteinModelPortali P60490.
    SMRi P60490. Positions 1-137.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 300852.TTHA1031.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAD70854 ; BAD70854 ; BAD70854 .
    GeneIDi 3168297.
    KEGGi ttj:TTHA1031.
    PATRICi 23957022. VBITheThe93045_1011.

    Phylogenomic databases

    eggNOGi COG0335.
    HOGENOMi HOG000016265.
    KOi K02884.
    OMAi KRIDQDR.
    OrthoDBi EOG6DZF5W.
    PhylomeDBi P60490.

    Enzyme and pathway databases

    BioCyci TTHE300852:GH8R-1063-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei P60490.

    Family and domain databases

    HAMAPi MF_00402. Ribosomal_L19.
    InterProi IPR001857. Ribosomal_L19.
    IPR018257. Ribosomal_L19_CS.
    IPR008991. Translation_prot_SH3-like.
    [Graphical view ]
    PANTHERi PTHR15680. PTHR15680. 1 hit.
    Pfami PF01245. Ribosomal_L19. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF002191. Ribosomal_L19. 1 hit.
    PRINTSi PR00061. RIBOSOMALL19.
    SUPFAMi SSF50104. SSF50104. 1 hit.
    TIGRFAMsi TIGR01024. rplS_bact. 1 hit.
    PROSITEi PS01015. RIBOSOMAL_L19. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Thermus thermophilus HB8."
      Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
      Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HB8 / ATCC 27634 / DSM 579.
    2. "Identification of the 50S ribosomal proteins from the eubacterium Thermus thermophilus."
      Katsani K.R., Tsiboli P., Anagnostopoulos K., Urlaub H., Choli-Papadopoulou T.
      Biol. Chem. 381:1079-1087(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 1-29.
    3. "Extending ribosomal protein identifications to unsequenced bacterial strains using matrix-assisted laser desorption/ionization mass spectrometry."
      Suh M.-J., Hamburg D.M., Gregory S.T., Dahlberg A.E., Limbach P.A.
      Proteomics 5:4818-4831(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: MASS SPECTROMETRY.
    4. "The path of messenger RNA through the ribosome."
      Yusupova G.Z., Yusupov M.M., Cate J.H.D., Noller H.F.
      Cell 106:233-241(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (5.0 ANGSTROMS) OF THE RIBOSOME.
    5. Cited for: X-RAY CRYSTALLOGRAPHY (5.5 ANGSTROMS) OF THE RIBOSOME, INTERSUBUNIT BRIDGE FORMATION.

    Entry informationi

    Entry nameiRL19_THET8
    AccessioniPrimary (citable) accession number: P60490
    Secondary accession number(s): Q5SJH7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 1, 2004
    Last sequence update: March 29, 2005
    Last modified: October 1, 2014
    This is version 93 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3