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P60489

- RL16_THET8

UniProt

P60489 - RL16_THET8

Protein

50S ribosomal protein L16

Gene

rplP

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 98 (01 Oct 2014)
      Sequence version 2 (29 Mar 2005)
      Previous versions | rss
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    Functioni

    This protein binds directly to 23S rRNA. Interacts with the A site tRNA.

    GO - Molecular functioni

    1. rRNA binding Source: UniProtKB-HAMAP
    2. structural constituent of ribosome Source: InterPro
    3. tRNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. translation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding, tRNA-binding

    Enzyme and pathway databases

    BioCyciTTHE300852:GH8R-1724-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    50S ribosomal protein L16
    Gene namesi
    Name:rplP
    Ordered Locus Names:TTHA1685
    OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
    Taxonomic identifieri300852 [NCBI]
    Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
    ProteomesiUP000000532: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. ribosome Source: UniProtKB-KW

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 14114150S ribosomal protein L16PRO_0000062237Add
    BLAST

    Interactioni

    Subunit structurei

    Part of the 50S ribosomal subunit.

    Protein-protein interaction databases

    STRINGi300852.TTHA1685.

    Structurei

    Secondary structure

    1
    141
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi5 – 84
    Beta strandi19 – 213
    Beta strandi22 – 243
    Beta strandi29 – 3810
    Beta strandi40 – 434
    Helixi44 – 5815
    Beta strandi59 – 613
    Beta strandi63 – 664
    Beta strandi72 – 765
    Beta strandi78 – 803
    Beta strandi83 – 853
    Beta strandi89 – 979
    Beta strandi102 – 1098
    Helixi111 – 12414
    Beta strandi125 – 1273
    Beta strandi129 – 1335
    Helixi135 – 1395

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1GIYX-ray5.50P1-141[»]
    1WKINMR-A1-141[»]
    1YL3X-ray5.50P1-141[»]
    2HGJX-ray5.00P1-141[»]
    2HGQX-ray5.50P1-140[»]
    2HGUX-ray4.51P1-140[»]
    2J01X-ray2.80Q1-141[»]
    2J03X-ray2.80Q1-141[»]
    2V47X-ray3.80Q1-141[»]
    2V49X-ray3.80Q1-141[»]
    2WDIX-ray3.30Q1-141[»]
    2WDJX-ray3.30Q1-141[»]
    2WDLX-ray3.50Q1-141[»]
    2WDNX-ray3.50Q1-141[»]
    2WH2X-ray3.45Q1-141[»]
    2WH4X-ray3.45Q1-141[»]
    2WRJX-ray3.60Q1-141[»]
    2WRLX-ray3.60Q1-141[»]
    2WROX-ray3.60Q1-141[»]
    2WRRX-ray3.60Q1-141[»]
    2X9SX-ray3.10Q1-141[»]
    2X9UX-ray3.10Q1-141[»]
    2XG0X-ray3.20Q1-141[»]
    2XG2X-ray3.20Q1-141[»]
    2XQEX-ray3.10Q1-141[»]
    2XTGelectron microscopy7.80Q1-141[»]
    2XUXelectron microscopy7.60Q1-141[»]
    2Y0VX-ray3.10Q1-141[»]
    2Y0XX-ray3.10Q1-141[»]
    2Y0ZX-ray3.10Q1-141[»]
    2Y11X-ray3.10Q1-141[»]
    2Y13X-ray3.10Q1-141[»]
    2Y15X-ray3.10Q1-141[»]
    2Y17X-ray3.10Q1-141[»]
    2Y19X-ray3.10Q1-141[»]
    3FINelectron microscopy6.40Q6-141[»]
    3HUXX-ray3.10Q1-141[»]
    3HUZX-ray3.10Q1-141[»]
    3I8FX-ray3.10P1-141[»]
    3I8IX-ray3.10P1-141[»]
    3I9CX-ray3.50P1-141[»]
    3I9EX-ray3.50P1-141[»]
    3KIRX-ray3.30Q1-141[»]
    3KITX-ray3.30Q1-141[»]
    3KIWX-ray3.60Q1-141[»]
    3KIYX-ray3.60Q1-141[»]
    3KNIX-ray3.00Q1-141[»]
    3KNKX-ray3.00Q1-141[»]
    3KNMX-ray3.45Q1-141[»]
    3KNOX-ray3.45Q1-141[»]
    3TVEX-ray3.10P1-141[»]
    3TVHX-ray3.10P1-141[»]
    3UXQX-ray3.20Q1-141[»]
    3UXRX-ray3.20Q1-141[»]
    3UYEX-ray3.00P1-141[»]
    3UYGX-ray3.00P1-141[»]
    3UZ1X-ray3.30P1-141[»]
    3UZ2X-ray3.30P1-141[»]
    3UZ8X-ray3.00P1-141[»]
    3UZ9X-ray3.00P1-141[»]
    3UZFX-ray3.30P1-141[»]
    3UZHX-ray3.30P1-141[»]
    3UZKX-ray3.30P1-141[»]
    3UZNX-ray3.30P1-141[»]
    3V23X-ray3.00Q1-141[»]
    3V25X-ray3.00Q1-141[»]
    3V27X-ray3.10Q1-141[»]
    3V29X-ray3.10Q1-141[»]
    3V2DX-ray2.70Q1-141[»]
    3V2FX-ray2.70Q1-141[»]
    3V6WX-ray3.90Q1-141[»]
    3V6XX-ray3.90Q1-141[»]
    3ZN9X-ray3.10Q1-141[»]
    3ZNEX-ray3.10Q1-141[»]
    3ZVPX-ray3.80Q1-141[»]
    4ABSX-ray3.10Q1-141[»]
    4B8GX-ray3.70Q1-141[»]
    4B8IX-ray3.70Q1-141[»]
    4BTDX-ray2.95Q1-141[»]
    4BYCX-ray3.35Q1-141[»]
    4BYEX-ray3.35Q1-141[»]
    4DHAX-ray3.20Q1-141[»]
    4DHCX-ray3.20Q1-141[»]
    4EJBX-ray3.52Q1-141[»]
    4EJCX-ray3.52Q1-141[»]
    4G5LX-ray3.30P1-141[»]
    4G5NX-ray3.30P1-141[»]
    4G5UX-ray3.10P1-141[»]
    4G5WX-ray3.10P1-141[»]
    4JUXX-ray2.86Q1-141[»]
    4K0MX-ray3.30Q1-141[»]
    4K0QX-ray3.30Q1-141[»]
    4NVVX-ray3.00Q1-141[»]
    4NVXX-ray3.00Q1-141[»]
    4NVZX-ray3.10Q1-141[»]
    4NW1X-ray3.10Q1-141[»]
    ProteinModelPortaliP60489.
    SMRiP60489. Positions 1-141.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP60489.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L16P family.Curated

    Phylogenomic databases

    eggNOGiCOG0197.
    HOGENOMiHOG000164573.
    KOiK02878.
    OMAiLKTTFVT.
    OrthoDBiEOG6WHNWS.
    PhylomeDBiP60489.

    Family and domain databases

    Gene3Di3.90.1170.10. 1 hit.
    HAMAPiMF_01342. Ribosomal_L16.
    InterProiIPR016180. Ribosomal_L10e/L16.
    IPR000114. Ribosomal_L16.
    [Graphical view]
    PANTHERiPTHR12220. PTHR12220. 1 hit.
    PfamiPF00252. Ribosomal_L16. 1 hit.
    [Graphical view]
    PRINTSiPR00060. RIBOSOMALL16.
    SUPFAMiSSF54686. SSF54686. 1 hit.
    TIGRFAMsiTIGR01164. rplP_bact. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P60489-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLMPRRMKYR KQQRGRLKGA TKGGDYVAFG DYGLVALEPA WITAQQIEAA    50
    RVAMVRHFRR GGKIFIRIFP DKPYTKKPLE VRMGKGKGNV EGYVAVVKPG 100
    RVMFEVAGVT EEQAMEALRI AGHKLPIKTK IVRRDAYDEA Q 141
    Length:141
    Mass (Da):15,963
    Last modified:March 29, 2005 - v2
    Checksum:i046579FBF9158EB2
    GO

    Mass spectrometryi

    Molecular mass is 15962 Da from positions 1 - 141. Determined by MALDI. 1 Publication

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008226 Genomic DNA. Translation: BAD71508.1.
    RefSeqiWP_011228846.1. NC_006461.1.
    YP_144951.1. NC_006461.1.

    Genome annotation databases

    EnsemblBacteriaiBAD71508; BAD71508; BAD71508.
    GeneIDi3168285.
    KEGGittj:TTHA1685.
    PATRICi23958325. VBITheThe93045_1655.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008226 Genomic DNA. Translation: BAD71508.1 .
    RefSeqi WP_011228846.1. NC_006461.1.
    YP_144951.1. NC_006461.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1GIY X-ray 5.50 P 1-141 [» ]
    1WKI NMR - A 1-141 [» ]
    1YL3 X-ray 5.50 P 1-141 [» ]
    2HGJ X-ray 5.00 P 1-141 [» ]
    2HGQ X-ray 5.50 P 1-140 [» ]
    2HGU X-ray 4.51 P 1-140 [» ]
    2J01 X-ray 2.80 Q 1-141 [» ]
    2J03 X-ray 2.80 Q 1-141 [» ]
    2V47 X-ray 3.80 Q 1-141 [» ]
    2V49 X-ray 3.80 Q 1-141 [» ]
    2WDI X-ray 3.30 Q 1-141 [» ]
    2WDJ X-ray 3.30 Q 1-141 [» ]
    2WDL X-ray 3.50 Q 1-141 [» ]
    2WDN X-ray 3.50 Q 1-141 [» ]
    2WH2 X-ray 3.45 Q 1-141 [» ]
    2WH4 X-ray 3.45 Q 1-141 [» ]
    2WRJ X-ray 3.60 Q 1-141 [» ]
    2WRL X-ray 3.60 Q 1-141 [» ]
    2WRO X-ray 3.60 Q 1-141 [» ]
    2WRR X-ray 3.60 Q 1-141 [» ]
    2X9S X-ray 3.10 Q 1-141 [» ]
    2X9U X-ray 3.10 Q 1-141 [» ]
    2XG0 X-ray 3.20 Q 1-141 [» ]
    2XG2 X-ray 3.20 Q 1-141 [» ]
    2XQE X-ray 3.10 Q 1-141 [» ]
    2XTG electron microscopy 7.80 Q 1-141 [» ]
    2XUX electron microscopy 7.60 Q 1-141 [» ]
    2Y0V X-ray 3.10 Q 1-141 [» ]
    2Y0X X-ray 3.10 Q 1-141 [» ]
    2Y0Z X-ray 3.10 Q 1-141 [» ]
    2Y11 X-ray 3.10 Q 1-141 [» ]
    2Y13 X-ray 3.10 Q 1-141 [» ]
    2Y15 X-ray 3.10 Q 1-141 [» ]
    2Y17 X-ray 3.10 Q 1-141 [» ]
    2Y19 X-ray 3.10 Q 1-141 [» ]
    3FIN electron microscopy 6.40 Q 6-141 [» ]
    3HUX X-ray 3.10 Q 1-141 [» ]
    3HUZ X-ray 3.10 Q 1-141 [» ]
    3I8F X-ray 3.10 P 1-141 [» ]
    3I8I X-ray 3.10 P 1-141 [» ]
    3I9C X-ray 3.50 P 1-141 [» ]
    3I9E X-ray 3.50 P 1-141 [» ]
    3KIR X-ray 3.30 Q 1-141 [» ]
    3KIT X-ray 3.30 Q 1-141 [» ]
    3KIW X-ray 3.60 Q 1-141 [» ]
    3KIY X-ray 3.60 Q 1-141 [» ]
    3KNI X-ray 3.00 Q 1-141 [» ]
    3KNK X-ray 3.00 Q 1-141 [» ]
    3KNM X-ray 3.45 Q 1-141 [» ]
    3KNO X-ray 3.45 Q 1-141 [» ]
    3TVE X-ray 3.10 P 1-141 [» ]
    3TVH X-ray 3.10 P 1-141 [» ]
    3UXQ X-ray 3.20 Q 1-141 [» ]
    3UXR X-ray 3.20 Q 1-141 [» ]
    3UYE X-ray 3.00 P 1-141 [» ]
    3UYG X-ray 3.00 P 1-141 [» ]
    3UZ1 X-ray 3.30 P 1-141 [» ]
    3UZ2 X-ray 3.30 P 1-141 [» ]
    3UZ8 X-ray 3.00 P 1-141 [» ]
    3UZ9 X-ray 3.00 P 1-141 [» ]
    3UZF X-ray 3.30 P 1-141 [» ]
    3UZH X-ray 3.30 P 1-141 [» ]
    3UZK X-ray 3.30 P 1-141 [» ]
    3UZN X-ray 3.30 P 1-141 [» ]
    3V23 X-ray 3.00 Q 1-141 [» ]
    3V25 X-ray 3.00 Q 1-141 [» ]
    3V27 X-ray 3.10 Q 1-141 [» ]
    3V29 X-ray 3.10 Q 1-141 [» ]
    3V2D X-ray 2.70 Q 1-141 [» ]
    3V2F X-ray 2.70 Q 1-141 [» ]
    3V6W X-ray 3.90 Q 1-141 [» ]
    3V6X X-ray 3.90 Q 1-141 [» ]
    3ZN9 X-ray 3.10 Q 1-141 [» ]
    3ZNE X-ray 3.10 Q 1-141 [» ]
    3ZVP X-ray 3.80 Q 1-141 [» ]
    4ABS X-ray 3.10 Q 1-141 [» ]
    4B8G X-ray 3.70 Q 1-141 [» ]
    4B8I X-ray 3.70 Q 1-141 [» ]
    4BTD X-ray 2.95 Q 1-141 [» ]
    4BYC X-ray 3.35 Q 1-141 [» ]
    4BYE X-ray 3.35 Q 1-141 [» ]
    4DHA X-ray 3.20 Q 1-141 [» ]
    4DHC X-ray 3.20 Q 1-141 [» ]
    4EJB X-ray 3.52 Q 1-141 [» ]
    4EJC X-ray 3.52 Q 1-141 [» ]
    4G5L X-ray 3.30 P 1-141 [» ]
    4G5N X-ray 3.30 P 1-141 [» ]
    4G5U X-ray 3.10 P 1-141 [» ]
    4G5W X-ray 3.10 P 1-141 [» ]
    4JUX X-ray 2.86 Q 1-141 [» ]
    4K0M X-ray 3.30 Q 1-141 [» ]
    4K0Q X-ray 3.30 Q 1-141 [» ]
    4NVV X-ray 3.00 Q 1-141 [» ]
    4NVX X-ray 3.00 Q 1-141 [» ]
    4NVZ X-ray 3.10 Q 1-141 [» ]
    4NW1 X-ray 3.10 Q 1-141 [» ]
    ProteinModelPortali P60489.
    SMRi P60489. Positions 1-141.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 300852.TTHA1685.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAD71508 ; BAD71508 ; BAD71508 .
    GeneIDi 3168285.
    KEGGi ttj:TTHA1685.
    PATRICi 23958325. VBITheThe93045_1655.

    Phylogenomic databases

    eggNOGi COG0197.
    HOGENOMi HOG000164573.
    KOi K02878.
    OMAi LKTTFVT.
    OrthoDBi EOG6WHNWS.
    PhylomeDBi P60489.

    Enzyme and pathway databases

    BioCyci TTHE300852:GH8R-1724-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei P60489.

    Family and domain databases

    Gene3Di 3.90.1170.10. 1 hit.
    HAMAPi MF_01342. Ribosomal_L16.
    InterProi IPR016180. Ribosomal_L10e/L16.
    IPR000114. Ribosomal_L16.
    [Graphical view ]
    PANTHERi PTHR12220. PTHR12220. 1 hit.
    Pfami PF00252. Ribosomal_L16. 1 hit.
    [Graphical view ]
    PRINTSi PR00060. RIBOSOMALL16.
    SUPFAMi SSF54686. SSF54686. 1 hit.
    TIGRFAMsi TIGR01164. rplP_bact. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Thermus thermophilus HB8."
      Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
      Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HB8 / ATCC 27634 / DSM 579.
    2. "Identification of the 50S ribosomal proteins from the eubacterium Thermus thermophilus."
      Katsani K.R., Tsiboli P., Anagnostopoulos K., Urlaub H., Choli-Papadopoulou T.
      Biol. Chem. 381:1079-1087(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 1-21.
    3. "Extending ribosomal protein identifications to unsequenced bacterial strains using matrix-assisted laser desorption/ionization mass spectrometry."
      Suh M.-J., Hamburg D.M., Gregory S.T., Dahlberg A.E., Limbach P.A.
      Proteomics 5:4818-4831(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: MASS SPECTROMETRY.
    4. "The path of messenger RNA through the ribosome."
      Yusupova G.Z., Yusupov M.M., Cate J.H.D., Noller H.F.
      Cell 106:233-241(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (5.0 ANGSTROMS) OF THE RIBOSOME.
    5. Cited for: X-RAY CRYSTALLOGRAPHY (5.5 ANGSTROMS) OF THE RIBOSOME.

    Entry informationi

    Entry nameiRL16_THET8
    AccessioniPrimary (citable) accession number: P60489
    Secondary accession number(s): Q5SHP5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 1, 2004
    Last sequence update: March 29, 2005
    Last modified: October 1, 2014
    This is version 98 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3