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P60486

- DAZP2_RAT

UniProt

P60486 - DAZP2_RAT

Protein

DAZ-associated protein 2

Gene

Dazap2

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Names & Taxonomyi

    Protein namesi
    Recommended name:
    DAZ-associated protein 2
    Alternative name(s):
    Deleted in azoospermia-associated protein 2
    Gene namesi
    Name:Dazap2
    OrganismiRattus norvegicus (Rat)
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 7

    Organism-specific databases

    RGDi1307407. Dazap2.

    Subcellular locationi

    Cytoplasm By similarity. Nucleus By similarity
    Note: Predominantly nuclear in macrophages, stimulation of IL17RB with its ligand IL17E induces accumulation in the cytoplasm.By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 108108DAZ-associated protein 2PRO_0000079790Add
    BLAST

    Post-translational modificationi

    Ubiquitinated by SMURF2, leading to proteasomal degradation.By similarity

    Keywords - PTMi

    Ubl conjugation

    Expressioni

    Gene expression databases

    GenevestigatoriP60486.

    Interactioni

    Subunit structurei

    Interacts with SOX6. Interacts with DAZ and DAZL By similarity. Interacts with IL17RB By similarity. May interact with FAM168B By similarity.By similarity

    Protein-protein interaction databases

    STRINGi10116.ENSRNOP00000006239.

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi66 – 705Poly-Pro

    Phylogenomic databases

    eggNOGiNOG43279.
    GeneTreeiENSGT00390000000685.
    HOGENOMiHOG000007683.
    HOVERGENiHBG051300.
    InParanoidiP60486.
    OMAiMNNKGSY.
    OrthoDBiEOG77HDG0.
    PhylomeDBiP60486.

    Family and domain databases

    InterProiIPR022730. DAZ_assoc-2.
    [Graphical view]
    PfamiPF11029. DAZAP2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P60486-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSAAFPGASL YLPMAQSVAV GPLGSTIPMA YYPVGPIYPP GSAVLVEGGY    50
    DAGARFGAGA TTGSIPPPPP GCPPNAAQLA VMQGANVLVT QRKGNFFMGG 100
    SDGGYTIW 108
    Length:108
    Mass (Da):10,775
    Last modified:March 1, 2004 - v1
    Checksum:iF197E40EA23A925D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC062052 mRNA. Translation: AAH62052.1.
    RefSeqiNP_001013125.1. NM_001013107.1.
    UniGeneiRn.107901.

    Genome annotation databases

    EnsembliENSRNOT00000006239; ENSRNOP00000006239; ENSRNOG00000004628.
    GeneIDi300235.
    KEGGirno:300235.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC062052 mRNA. Translation: AAH62052.1 .
    RefSeqi NP_001013125.1. NM_001013107.1.
    UniGenei Rn.107901.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10116.ENSRNOP00000006239.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000006239 ; ENSRNOP00000006239 ; ENSRNOG00000004628 .
    GeneIDi 300235.
    KEGGi rno:300235.

    Organism-specific databases

    CTDi 9802.
    RGDi 1307407. Dazap2.

    Phylogenomic databases

    eggNOGi NOG43279.
    GeneTreei ENSGT00390000000685.
    HOGENOMi HOG000007683.
    HOVERGENi HBG051300.
    InParanoidi P60486.
    OMAi MNNKGSY.
    OrthoDBi EOG77HDG0.
    PhylomeDBi P60486.

    Miscellaneous databases

    NextBioi 646601.

    Gene expression databases

    Genevestigatori P60486.

    Family and domain databases

    InterProi IPR022730. DAZ_assoc-2.
    [Graphical view ]
    Pfami PF11029. DAZAP2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Prostate.

    Entry informationi

    Entry nameiDAZP2_RAT
    AccessioniPrimary (citable) accession number: P60486
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 1, 2004
    Last sequence update: March 1, 2004
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    External Data

    Dasty 3