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P60486 (DAZP2_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
DAZ-associated protein 2
Alternative name(s):
Deleted in azoospermia-associated protein 2
Gene names
Name:Dazap2
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length108 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Subunit structure

Interacts with SOX6. Interacts with DAZ and DAZL By similarity. Interacts with IL17RB By similarity. May interact with FAM168B By similarity.

Subcellular location

Cytoplasm By similarity. Nucleus By similarity. Note: Predominantly nuclear in macrophages, stimulation of IL17RB with its ligand IL17E induces accumulation in the cytoplasm By similarity.

Post-translational modification

Ubiquitinated by SMURF2, leading to proteasomal degradation By similarity.

Ontologies

Keywords
   Cellular componentCytoplasm
Nucleus
   PTMUbl conjugation
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

nucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 108108DAZ-associated protein 2
PRO_0000079790

Regions

Compositional bias66 – 705Poly-Pro

Sequences

Sequence LengthMass (Da)Tools
P60486 [UniParc].

Last modified March 1, 2004. Version 1.
Checksum: F197E40EA23A925D

FASTA10810,775
        10         20         30         40         50         60 
MSAAFPGASL YLPMAQSVAV GPLGSTIPMA YYPVGPIYPP GSAVLVEGGY DAGARFGAGA 

        70         80         90        100 
TTGSIPPPPP GCPPNAAQLA VMQGANVLVT QRKGNFFMGG SDGGYTIW 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Prostate.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC062052 mRNA. Translation: AAH62052.1.
RefSeqNP_001013125.1. NM_001013107.1.
UniGeneRn.107901.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10116.ENSRNOP00000006239.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000006239; ENSRNOP00000006239; ENSRNOG00000004628.
GeneID300235.
KEGGrno:300235.

Organism-specific databases

CTD9802.
RGD1307407. Dazap2.

Phylogenomic databases

eggNOGNOG43279.
GeneTreeENSGT00390000000685.
HOGENOMHOG000007683.
HOVERGENHBG051300.
InParanoidP60486.
OMAMNNKGSY.
OrthoDBEOG77HDG0.
PhylomeDBP60486.

Gene expression databases

GenevestigatorP60486.

Family and domain databases

InterProIPR022730. DAZ_assoc-2.
[Graphical view]
PfamPF11029. DAZAP2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio646601.

Entry information

Entry nameDAZP2_RAT
AccessionPrimary (citable) accession number: P60486
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 2004
Last sequence update: March 1, 2004
Last modified: April 16, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program