##gff-version 3
P60483	UniProtKB	Initiator methionine	1	1	.	.	.	Note=Removed;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P60484	
P60483	UniProtKB	Chain	2	403	.	.	.	ID=PRO_0000215903;Note=Phosphatidylinositol 3%2C4%2C5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	
P60483	UniProtKB	Domain	14	185	.	.	.	Note=Phosphatase tensin-type;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00590	
P60483	UniProtKB	Domain	190	350	.	.	.	Note=C2 tensin-type;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00589	
P60483	UniProtKB	Region	338	348	.	.	.	Note=Required for interaction with NOP53;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P60484	
P60483	UniProtKB	Region	352	403	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P60483	UniProtKB	Motif	401	403	.	.	.	Note=PDZ domain-binding;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O08586	
P60483	UniProtKB	Compositional bias	353	370	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P60483	UniProtKB	Compositional bias	371	385	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P60483	UniProtKB	Active site	124	124	.	.	.	Note=Phosphocysteine intermediate;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00590	
P60483	UniProtKB	Modified residue	2	2	.	.	.	Note=N-acetylthreonine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P60484	
P60483	UniProtKB	Modified residue	294	294	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O08586	
P60483	UniProtKB	Modified residue	319	319	.	.	.	Note=Phosphothreonine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P60484	
P60483	UniProtKB	Modified residue	321	321	.	.	.	Note=Phosphothreonine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P60484	
P60483	UniProtKB	Modified residue	336	336	.	.	.	Note=Phosphotyrosine%3B by FRK;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P60484	
P60483	UniProtKB	Modified residue	366	366	.	.	.	Note=Phosphothreonine%3B by GSK3-beta and PLK3;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P60484	
P60483	UniProtKB	Modified residue	370	370	.	.	.	Note=Phosphoserine%3B by CK2 and PLK3;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P60484	
P60483	UniProtKB	Modified residue	380	380	.	.	.	Note=Phosphoserine%3B by ROCK1;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P60484	
P60483	UniProtKB	Modified residue	382	382	.	.	.	Note=Phosphothreonine%3B by ROCK1;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P60484	
P60483	UniProtKB	Modified residue	383	383	.	.	.	Note=Phosphothreonine%3B by ROCK1;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P60484	
P60483	UniProtKB	Modified residue	385	385	.	.	.	Note=Phosphoserine%3B by CK2;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P60484	
P60483	UniProtKB	Modified residue	401	401	.	.	.	Note=Phosphothreonine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P60484	
P60483	UniProtKB	Cross-link	13	13	.	.	.	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin);Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P60484	
P60483	UniProtKB	Cross-link	289	289	.	.	.	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin);Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P60484