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Protein

Preprotein translocase subunit SecG

Gene

secG

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Subunit of the protein translocation channel SecYEG. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Preprotein translocase subunit SecG
Alternative name(s):
Protein transport protein Sec61 subunit beta homolog
Gene namesi
Name:secG
Ordered Locus Names:MJ0912.1
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
Proteomesi
  • UP000000805 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 3030CytoplasmicAdd
BLAST
Transmembranei31 – 4919HelicalAdd
BLAST
Topological domaini50 – 534Extracellular

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 5353Preprotein translocase subunit SecGPRO_0000157268Add
BLAST

Interactioni

Subunit structurei

Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.1 Publication

Protein-protein interaction databases

IntActiP60460. 2 interactions.
MINTiMINT-8378640.

Structurei

Secondary structure

1
53
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi30 – 4920Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1RH5X-ray3.20C1-53[»]
1RHZX-ray3.50C1-53[»]
2YXQX-ray3.50C1-53[»]
2YXRX-ray3.60C1-53[»]
3BO0electron microscopy9.60C21-52[»]
3BO1electron microscopy9.60C21-52[»]
3DKNelectron microscopy8.70C21-52[»]
4V4Nelectron microscopy9.00A81-52[»]
4V7Ielectron microscopy9.60AC1-53[»]
ProteinModelPortaliP60460.
SMRiP60460. Positions 21-52.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP60460.

Family & Domainsi

Sequence similaritiesi

Belongs to the SEC61-beta family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

OMAiGLIRYMD.

Family and domain databases

HAMAPiMF_00751. SecG. 1 hit.
InterProiIPR023531. Preprot_translocase_SecG.
IPR016482. SecG/Sec61-beta/Sbh.
[Graphical view]
PfamiPF03911. Sec61_beta. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P60460-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKREETGLA TSAGLIRYMD ETFSKIRVKP EHVIGVTVAF VIIEAILTYG

RFL
Length:53
Mass (Da):5,959
Last modified:February 16, 2004 - v1
Checksum:iD2D5DD22331BE2AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. No translation available.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. No translation available.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1RH5X-ray3.20C1-53[»]
1RHZX-ray3.50C1-53[»]
2YXQX-ray3.50C1-53[»]
2YXRX-ray3.60C1-53[»]
3BO0electron microscopy9.60C21-52[»]
3BO1electron microscopy9.60C21-52[»]
3DKNelectron microscopy8.70C21-52[»]
4V4Nelectron microscopy9.00A81-52[»]
4V7Ielectron microscopy9.60AC1-53[»]
ProteinModelPortaliP60460.
SMRiP60460. Positions 21-52.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP60460. 2 interactions.
MINTiMINT-8378640.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

OMAiGLIRYMD.

Miscellaneous databases

EvolutionaryTraceiP60460.

Family and domain databases

HAMAPiMF_00751. SecG. 1 hit.
InterProiIPR023531. Preprot_translocase_SecG.
IPR016482. SecG/Sec61-beta/Sbh.
[Graphical view]
PfamiPF03911. Sec61_beta. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSECG_METJA
AccessioniPrimary (citable) accession number: P60460
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: February 16, 2004
Last modified: December 9, 2015
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.