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P60347 (TRUD_GEOSL) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
tRNA pseudouridine synthase D

EC=5.4.99.27
Alternative name(s):
tRNA pseudouridine(13) synthase
tRNA pseudouridylate synthase D
tRNA-uridine isomerase D
Gene names
Name:truD
Ordered Locus Names:GSU0520
OrganismGeobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) [Reference proteome] [HAMAP]
Taxonomic identifier243231 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter

Protein attributes

Sequence length408 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs By similarity. HAMAP-Rule MF_01082

Catalytic activity

tRNA uridine13 = tRNA pseudouridine13. HAMAP-Rule MF_01082

Sequence similarities

Belongs to the pseudouridine synthase TruD family.

Contains 1 TRUD domain.

Ontologies

Keywords
   Biological processtRNA processing
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtRNA pseudouridine synthesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: InterPro

pseudouridine synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 408408tRNA pseudouridine synthase D HAMAP-Rule MF_01082
PRO_0000152499

Regions

Domain157 – 367211TRUD

Sites

Active site821Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
P60347 [UniParc].

Last modified February 16, 2004. Version 1.
Checksum: 04BE7A4013CEB7C8

FASTA40845,099
        10         20         30         40         50         60 
MARDEHDSRY LTAELPGTGG LFKETPEDFL VEEISLYLPC GEGEHTYAVI EKRGITTLEA 

        70         80         90        100        110        120 
IRRLCRATGA PERDTGYAGM KDARGITRQT VSLPRVTPAE VMGLNIPGIR ILSADRHRNK 

       130        140        150        160        170        180 
LRLGHLAGNR FRLRLRETVP DAADRARAIL DVLARRGVPN RFGEQRYGIQ GNSHLVGRAM 

       190        200        210        220        230        240 
LAGDWRGAVD LLMGDPAKVE GERWRAAIEA YRQGDLAGSL SLFPGHCRTE RDVLQRLAKR 

       250        260        270        280        290        300 
PDDFERAVHG VHPRLKKLYL SACQSALFDR VLETRLQTID HVMEGDLAWK HDNGACFLVT 

       310        320        330        340        350        360 
DAKAEAPRAE RFEISPTGPL FGCRMTSPEG EPAALEKSIL DAAGLTPAAF NLAGGLRMEG 

       370        380        390        400 
ERRPLRVPLE GPELSCEEED LVLRFSLPRG SYATAVLREV MKRPGNGA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017180 Genomic DNA. Translation: AAR33851.1.
RefSeqNP_951578.1. NC_002939.5.

3D structure databases

ProteinModelPortalP60347.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243231.GSU0520.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAR33851; AAR33851; GSU0520.
GeneID2686060.
KEGGgsu:GSU0520.
PATRIC22023795. VBIGeoSul17553_0521.

Phylogenomic databases

eggNOGCOG0585.
HOGENOMHOG000224848.
KOK06176.
OMALRYERAM.
OrthoDBEOG6FRCSP.
ProtClustDBCLSK827897.

Enzyme and pathway databases

BioCycGSUL243231:GH27-525-MONOMER.

Family and domain databases

HAMAPMF_01082. TruD.
InterProIPR020103. PsdUridine_synth_cat_dom.
IPR001656. PsdUridine_synth_TruD.
IPR020119. PsdUridine_synth_TruD_CS.
IPR011760. PsdUridine_synth_TruD_insert.
[Graphical view]
PANTHERPTHR13326. PTHR13326. 1 hit.
PfamPF01142. TruD. 1 hit.
[Graphical view]
SUPFAMSSF55120. SSF55120. 2 hits.
TIGRFAMsTIGR00094. tRNA_TruD_broad. 1 hit.
PROSITEPS50984. TRUD. 1 hit.
PS01268. UPF0024. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTRUD_GEOSL
AccessionPrimary (citable) accession number: P60347
Entry history
Integrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: February 16, 2004
Last modified: February 19, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families