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Protein

Inactive ribonuclease-like protein 9

Gene

Rnase9

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Does not exhibit any ribonuclease activity.By similarity

GO - Molecular functioni

  1. nucleic acid binding Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Inactive ribonuclease-like protein 9
Gene namesi
Name:Rnase9
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:3057273. Rnase9.

Subcellular locationi

Secreted Curated

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525Sequence AnalysisAdd
BLAST
Chaini26 – 184159Inactive ribonuclease-like protein 9PRO_0000030956Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi93 ↔ 148By similarity
Disulfide bondi111 ↔ 163By similarity
Disulfide bondi118 ↔ 125By similarity
Glycosylationi147 – 1471N-linked (GlcNAc...)Sequence Analysis
Glycosylationi179 – 1791N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PRIDEiP60154.

PTM databases

PhosphoSiteiP60154.

Expressioni

Gene expression databases

BgeeiP60154.
CleanExiMM_RNASE9.
GenevestigatoriP60154.

Structurei

3D structure databases

ProteinModelPortaliP60154.
SMRiP60154. Positions 77-176.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pancreatic ribonuclease family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG46399.
HOGENOMiHOG000139362.
HOVERGENiHBG056874.
InParanoidiP60154.
OMAiKNGIRKC.
OrthoDBiEOG7XDBHR.
PhylomeDBiP60154.
TreeFamiTF338401.

Family and domain databases

Gene3Di3.10.130.10. 1 hit.
InterProiIPR029741. RNASE9.
IPR001427. RNaseA.
IPR023412. RNaseA_domain.
[Graphical view]
PANTHERiPTHR11437. PTHR11437. 1 hit.
PTHR11437:SF14. PTHR11437:SF14. 1 hit.
PfamiPF00074. RnaseA. 1 hit.
[Graphical view]
ProDomiPD000535. RNaseA. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54076. SSF54076. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P60154-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPLVIKFAW PLPLLLLLLL PPKLQGNYWD FGEYELNPEV RDFIREYEST
60 70 80 90 100
GPTKPPTVKR IIEMITIGDQ PFNDYDYCNT ELRTKQIHYK GRCYPEHYIA
110 120 130 140 150
GVPYGELVKA CDGEEVQCKN GVKSCRRSMN LIEGVRCVLE TGQQMTNCTY
160 170 180
KTILMIGYPV VSCQWDEETK IFIPDHIYNM SLPK
Length:184
Mass (Da):21,378
Last modified:November 27, 2003 - v1
Checksum:i89B3A112C06066C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY226989 mRNA. Translation: AAP43946.1.
CCDSiCCDS36909.1.
RefSeqiNP_898853.2. NM_183032.2.
XP_006519205.1. XM_006519142.2.
UniGeneiMm.99528.

Genome annotation databases

EnsembliENSMUST00000064214; ENSMUSP00000066637; ENSMUSG00000052382.
GeneIDi328401.
KEGGimmu:328401.
UCSCiuc007tmh.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY226989 mRNA. Translation: AAP43946.1.
CCDSiCCDS36909.1.
RefSeqiNP_898853.2. NM_183032.2.
XP_006519205.1. XM_006519142.2.
UniGeneiMm.99528.

3D structure databases

ProteinModelPortaliP60154.
SMRiP60154. Positions 77-176.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSiteiP60154.

Proteomic databases

PRIDEiP60154.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000064214; ENSMUSP00000066637; ENSMUSG00000052382.
GeneIDi328401.
KEGGimmu:328401.
UCSCiuc007tmh.1. mouse.

Organism-specific databases

CTDi390443.
MGIiMGI:3057273. Rnase9.

Phylogenomic databases

eggNOGiNOG46399.
HOGENOMiHOG000139362.
HOVERGENiHBG056874.
InParanoidiP60154.
OMAiKNGIRKC.
OrthoDBiEOG7XDBHR.
PhylomeDBiP60154.
TreeFamiTF338401.

Miscellaneous databases

NextBioi398285.
PROiP60154.
SOURCEiSearch...

Gene expression databases

BgeeiP60154.
CleanExiMM_RNASE9.
GenevestigatoriP60154.

Family and domain databases

Gene3Di3.10.130.10. 1 hit.
InterProiIPR029741. RNASE9.
IPR001427. RNaseA.
IPR023412. RNaseA_domain.
[Graphical view]
PANTHERiPTHR11437. PTHR11437. 1 hit.
PTHR11437:SF14. PTHR11437:SF14. 1 hit.
PfamiPF00074. RnaseA. 1 hit.
[Graphical view]
ProDomiPD000535. RNaseA. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54076. SSF54076. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Discovery in silico and characterization in vitro of novel genes exclusively expressed in the mouse epididymis."
    Penttinen J., Pujianto D.A., Sipilae P., Huhtaniemi I., Poutanen M.
    Mol. Endocrinol. 17:2138-2151(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: FVB/N.
    Tissue: Epididymis.

Entry informationi

Entry nameiRNAS9_MOUSE
AccessioniPrimary (citable) accession number: P60154
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 27, 2003
Last sequence update: November 27, 2003
Last modified: March 31, 2015
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.