P60154 (RNAS9_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Inactive ribonuclease-like protein 9

Gene names

Name:

Rnase9

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	184 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Does not exhibit any ribonuclease activity By similarity.
Subcellular location	Secreted Probable.
Sequence similarities	Belongs to the pancreatic ribonuclease family.

Ontologies

Keywords
Cellular component	Secreted
Domain	Signal
PTM	Disulfide bond Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	nucleic acid binding Inferred from electronic annotation. Source: InterPro pancreatic ribonuclease activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 25	25	Potential
	Chain	26 – 184	159	Inactive ribonuclease-like protein 9		PRO_0000030956
Amino acid modifications
	Glycosylation	147	1	N-linked (GlcNAc...) Potential
	Glycosylation	179	1	N-linked (GlcNAc...) Potential
	Disulfide bond	93 ↔ 148		By similarity
	Disulfide bond	111 ↔ 163		By similarity
	Disulfide bond	118 ↔ 125		By similarity

Sequences

	Sequence		Length	Mass (Da)
	P60154 [UniParc]. Last modified November 28, 2003. Version 1. Checksum: 89B3A112C06066C3	FASTA	184	21,378
	10 20 30 40 50 60 MKPLVIKFAW PLPLLLLLLL PPKLQGNYWD FGEYELNPEV RDFIREYEST GPTKPPTVKR 70 80 90 100 110 120 IIEMITIGDQ PFNDYDYCNT ELRTKQIHYK GRCYPEHYIA GVPYGELVKA CDGEEVQCKN 130 140 150 160 170 180 GVKSCRRSMN LIEGVRCVLE TGQQMTNCTY KTILMIGYPV VSCQWDEETK IFIPDHIYNM SLPK

References

[1]	"Discovery in silico and characterization in vitro of novel genes exclusively expressed in the mouse epididymis." Penttinen J., Pujianto D.A., Sipilae P., Huhtaniemi I., Poutanen M. Mol. Endocrinol. 17:2138-2151(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: FVB/N. Tissue: Epididymis.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY226989 mRNA. Translation: AAP43946.1.
IPI	IPI00395128.
RefSeq	NP_898853.2. NM_183032.2.
UniGene	Mm.99528.
3D structure databases
ProteinModelPortal	P60154.
SMR	P60154. Positions 77-176.
ModBase	Search...
PTM databases
PhosphoSite	P60154.
Proteomic databases
PRIDE	P60154.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000064214; ENSMUSP00000066637; ENSMUSG00000052382.
GeneID	328401.
KEGG	mmu:328401.
Organism-specific databases
CTD	390443.
MGI	MGI:3057273. Rnase9.
Phylogenomic databases
eggNOG	NOG46399.
HOGENOM	HOG000139362.
HOVERGEN	HBG056874.
InParanoid	P60154.
OMA	CKNGIRK.
OrthoDB	EOG46WZ9K.
Gene expression databases
ArrayExpress	P60154.
Bgee	P60154.
CleanEx	MM_RNASE9.
Genevestigator	P60154.
Family and domain databases
Gene3D	3.10.130.10. 1 hit.
InterPro	IPR001427. RNaseA. IPR023412. RNaseA_domain. [Graphical view]
PANTHER	PTHR11437. PTHR11437. 1 hit.
Pfam	PF00074. RnaseA. 1 hit. [Graphical view]
ProDom	PD000535. RNaseA. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF54076. RNaseA. 1 hit.
ProtoNet	Search...
Other
NextBio	398285.
SOURCE	Search...

Entry information

Entry name

RNAS9_MOUSE

Accession

Primary (citable) accession number: P60154

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2003
Last sequence update:	November 28, 2003
Last modified:	May 1, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program