P60112 (ATP9_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
ATP synthase subunit 9, mitochondrial

Alternative name(s):
Lipid-binding protein

Gene names

Name:	ATP9
Ordered Locus Names:	AtMg01080

Encoded on

Mitochondrion

Organism

Arabidopsis thaliana (Mouse-ear cress)

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	85 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	This protein is one of the chains of the nonenzymatic membrane component (F0) of mitochondrial ATPase.
Subunit structure	F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a, b and c By similarity.
Subcellular location	Mitochondrion membrane; Multi-pass membrane protein Potential.
Miscellaneous	A stretch of 270 kb of the mitochondrial genome is duplicated within the centromere of chromosome 2 resulting in the duplication of the gene. The expression of this duplicated gene (At2g07671) is not demonstrated. It is also probably not RNA edited and therefore differs in all the positions known to be edited.
Sequence similarities	Belongs to the ATPase C chain family.
RNA editing	Edited at positions 18, 28, 56 and 75. Ref.5
Sequence caution	The sequence AAM15515.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Biological process	Hydrogen ion transport Ion transport Transport
Cellular component	CF(0) Membrane Mitochondrion
Coding sequence diversity	RNA editing
Domain	Transmembrane Transmembrane helix
Ligand	ATP-binding Lipid-binding Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	ATP hydrolysis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW lipid binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 85	85	ATP synthase subunit 9, mitochondrial		PRO_0000112208
Regions
	Transmembrane	19 – 39	21	Helical; Potential
	Transmembrane	61 – 81	21	Helical; By similarity
Sites
	Site	68	1	Reversibly protonated during proton transport By similarity

Sequences

	Sequence		Length	Mass (Da)
	P60112 [UniParc]. Last modified September 5, 2006. Version 2. Checksum: D95420E7A0BDB9C7	FASTA	85	8,936
	10 20 30 40 50 60 MTKREYNSQP EMLEGAKLIG AGAATIALAG AAIGIGNVFS SLIHSVARNP SLAKQLFGYA 70 80 ILGFALTEAI ALFALMMAFL ILFVF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Altered mitochondrial gene expression in a maternal distorted leaf mutant of Arabidopsis induced by chloroplast mutator." Sakamoto W., Kondo H., Murata M., Motoyoshi F. Plant Cell 8:1377-1390(1996) [PubMed: 8776901] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: cv. Landsberg erecta.
[2]	"The mitochondrial genome of Arabidopsis thaliana contains 57 genes in 366,924 nucleotides." Unseld M., Marienfeld J.R., Brandt P., Brennicke A. Nat. Genet. 15:57-61(1997) [PubMed: 8988169] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[3]	"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana." Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C. Nature 402:761-768(1999) [PubMed: 10617197] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (AT2G07671). Strain: cv. Columbia.
[4]	"Genetic architecture of mitochondrial editing in Arabidopsis thaliana." Bentolila S., Elliott L.E., Hanson M.R. Genetics 178:1693-1708(2008) [PubMed: 17565941] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 17-78, RNA-EDITING. Strain: cv. Columbia and cv. Landsberg erecta. Tissue: Rosette leaf.
[5]	"RNA editing in Arabidopsis mitochondria effects 441 C to U changes in ORFs." Giege P., Brennicke A. Proc. Natl. Acad. Sci. U.S.A. 96:15324-15329(1999) [PubMed: 10611383] [Abstract] Cited for: RNA EDITING.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D82062 Genomic DNA. Translation: BAA11530.1. Sequence problems. Y08501 Genomic DNA. Translation: CAA69793.3. Sequence problems. AC007730 Genomic DNA. Translation: AAM15515.1. Sequence problems. EF488892 mRNA. Translation: ABS50604.1. EF488893 mRNA. Translation: ABS50605.1.
IPI	IPI00785905.
RefSeq	NP_085561.2. NC_001284.2. NP_178769.2. NM_126728.2.
UniGene	At.48433. At.66173.
3D structure databases
ProteinModelPortal	P60112.
SMR	P60112. Positions 15-83.
ModBase	Search...
Protein-protein interaction databases
IntAct	P60112. 2 interactions.
STRING	P60112.
Proteomic databases
PRIDE	P60112.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	814613. 815343.
GenomeReviews	Gene locus ATMG01080 in contig Y08501_GR.
KEGG	ath:ArthMp094. ath:AT2G07671.
Organism-specific databases
TAIR	AtMg01080.
Phylogenomic databases
HOGENOM	HBG753983.
PhylomeDB	P60112.
ProtClustDB	CLSN2718092.
Gene expression databases
Genevestigator	P60112.
GermOnline	ATMG01080. Arabidopsis thaliana.
Family and domain databases
InterPro	IPR000454. ATPase_F0-cplx_csu. IPR020537. ATPase_F0-cplx_csu_DDCD_BS. IPR002379. ATPase_F0/V0-cplx_csu. [Graphical view]
Gene3D	G3DSA:1.20.20.10. ATPase_F0/V0_c. 1 hit.
KO	K02128.
Pfam	PF00137. ATP-synt_C. 1 hit. [Graphical view]
PRINTS	PR00124. ATPASEC.
SUPFAM	SSF81333. ATPase_F0/V0_c. 1 hit.
PROSITE	PS00605. ATPASE_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ATP9_ARATH

Accession

Primary (citable) accession number: P60112
Secondary accession number(s): A7KNE9, Q08366, Q8S875

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2003
Last sequence update:	September 5, 2006
Last modified:	January 25, 2012
This is version 75 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program