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P60053

- ALF1_PORGI

UniProt

P60053 - ALF1_PORGI

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Protein

Fructose-bisphosphate aldolase class 1

Gene

fda

Organism
Porphyromonas gingivalis (strain ATCC BAA-308 / W83)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Catalytic activityi

D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei176 – 1761Proton acceptorUniRule annotation
Active sitei211 – 2111Schiff-base intermediate with dihydroxyacetone-PUniRule annotation

GO - Molecular functioni

  1. fructose-bisphosphate aldolase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

Schiff base

Enzyme and pathway databases

BioCyciPGIN242619:GHX8-1583-MONOMER.
UniPathwayiUPA00109; UER00183.

Names & Taxonomyi

Protein namesi
Recommended name:
Fructose-bisphosphate aldolase class 1UniRule annotation (EC:4.1.2.13UniRule annotation)
Alternative name(s):
Fructose-bisphosphate aldolase class I
Short name:
FBP aldolaseUniRule annotation
Gene namesi
Name:fdaUniRule annotation
Synonyms:fbaB
Ordered Locus Names:PG_1755
OrganismiPorphyromonas gingivalis (strain ATCC BAA-308 / W83)
Taxonomic identifieri242619 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesPorphyromonadaceaePorphyromonas
ProteomesiUP000000588: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 293293Fructose-bisphosphate aldolase class 1PRO_0000216902Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi242619.PG1755.

Structurei

Secondary structure

293
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi1 – 1111Combined sources
Beta strandi14 – 196Combined sources
Helixi23 – 253Combined sources
Helixi26 – 327Combined sources
Helixi37 – 393Combined sources
Helixi43 – 5917Combined sources
Helixi61 – 644Combined sources
Beta strandi65 – 739Combined sources
Helixi75 – 784Combined sources
Beta strandi80 – 823Combined sources
Helixi87 – 959Combined sources
Beta strandi98 – 1025Combined sources
Helixi123 – 13210Combined sources
Beta strandi137 – 1448Combined sources
Helixi149 – 16719Combined sources
Turni168 – 1703Combined sources
Beta strandi172 – 1798Combined sources
Helixi186 – 20318Combined sources
Beta strandi208 – 2136Combined sources
Turni218 – 2214Combined sources
Helixi222 – 2254Combined sources
Beta strandi230 – 2367Combined sources
Helixi242 – 2498Combined sources
Beta strandi256 – 2605Combined sources
Helixi261 – 2644Combined sources
Helixi273 – 29220Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2IQTX-ray2.46A1-293[»]
ProteinModelPortaliP60053.
SMRiP60053. Positions 1-293.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP60053.

Family & Domainsi

Sequence similaritiesi

Belongs to the class I fructose-bisphosphate aldolase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG3588.
KOiK01623.
OMAiANCARAK.
OrthoDBiEOG6M6JJT.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00729. FBP_aldolase_1.
InterProiIPR013785. Aldolase_TIM.
IPR000741. FBA_I.
IPR023014. FBA_I_Gram+-type.
[Graphical view]
PfamiPF00274. Glycolytic. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P60053-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNKEQLQQMR QAPGFVGALD QSGGSTPKAL KAYGIQPDAY QSEEEMFDLI
60 70 80 90 100
HQMRTRMITS PAFATGKIIG VILFERTMRG KIEGMPTADF LWEKRHIVPF
110 120 130 140 150
LKVDKGLQDE ANGVQLMKPF PELGKLCEEA VGYHVFGTKM RSVIKQANEQ
160 170 180 190 200
GIRDIVEQQF QWGKEILSHG LVPILEPEVD IHCPEKAKAE EILKRELLAQ
210 220 230 240 250
LDKMTEPVML KITIPTVDNF YKEIIEHPMM LRVVALSGGY SREQANELLS
260 270 280 290
RNHGVIASFS RALVEGLSAR QTDAEFNAML EASIEDVYQA SIK
Length:293
Mass (Da):32,987
Last modified:November 21, 2003 - v1
Checksum:i8BF85BFF649DCE93
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015924 Genomic DNA. Translation: AAQ66757.1.
RefSeqiNP_905858.1. NC_002950.2.

Genome annotation databases

EnsemblBacteriaiAAQ66757; AAQ66757; PG_1755.
GeneIDi2552379.
KEGGipgi:PG1755.
PATRICi22980496. VBIPorGin134034_1622.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015924 Genomic DNA. Translation: AAQ66757.1 .
RefSeqi NP_905858.1. NC_002950.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2IQT X-ray 2.46 A 1-293 [» ]
ProteinModelPortali P60053.
SMRi P60053. Positions 1-293.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 242619.PG1755.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAQ66757 ; AAQ66757 ; PG_1755 .
GeneIDi 2552379.
KEGGi pgi:PG1755.
PATRICi 22980496. VBIPorGin134034_1622.

Phylogenomic databases

eggNOGi COG3588.
KOi K01623.
OMAi ANCARAK.
OrthoDBi EOG6M6JJT.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00183 .
BioCyci PGIN242619:GHX8-1583-MONOMER.

Miscellaneous databases

EvolutionaryTracei P60053.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00729. FBP_aldolase_1.
InterProi IPR013785. Aldolase_TIM.
IPR000741. FBA_I.
IPR023014. FBA_I_Gram+-type.
[Graphical view ]
Pfami PF00274. Glycolytic. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-308 / W83.

Entry informationi

Entry nameiALF1_PORGI
AccessioniPrimary (citable) accession number: P60053
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 21, 2003
Last sequence update: November 21, 2003
Last modified: October 29, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3