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P60053

- ALF1_PORGI

UniProt

P60053 - ALF1_PORGI

Protein

Fructose-bisphosphate aldolase class 1

Gene

fda

Organism
Porphyromonas gingivalis (strain ATCC BAA-308 / W83)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (21 Nov 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei176 – 1761Proton acceptorUniRule annotation
    Active sitei211 – 2111Schiff-base intermediate with dihydroxyacetone-PUniRule annotation

    GO - Molecular functioni

    1. fructose-bisphosphate aldolase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    Schiff base

    Enzyme and pathway databases

    BioCyciPGIN242619:GHX8-1583-MONOMER.
    UniPathwayiUPA00109; UER00183.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Fructose-bisphosphate aldolase class 1UniRule annotation (EC:4.1.2.13UniRule annotation)
    Alternative name(s):
    Fructose-bisphosphate aldolase class I
    Short name:
    FBP aldolaseUniRule annotation
    Gene namesi
    Name:fdaUniRule annotation
    Synonyms:fbaB
    Ordered Locus Names:PG_1755
    OrganismiPorphyromonas gingivalis (strain ATCC BAA-308 / W83)
    Taxonomic identifieri242619 [NCBI]
    Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesPorphyromonadaceaePorphyromonas
    ProteomesiUP000000588: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 293293Fructose-bisphosphate aldolase class 1PRO_0000216902Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi242619.PG1755.

    Structurei

    Secondary structure

    293
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi1 – 1111
    Beta strandi14 – 196
    Helixi23 – 253
    Helixi26 – 327
    Helixi37 – 393
    Helixi43 – 5917
    Helixi61 – 644
    Beta strandi65 – 739
    Helixi75 – 784
    Beta strandi80 – 823
    Helixi87 – 959
    Beta strandi98 – 1025
    Helixi123 – 13210
    Beta strandi137 – 1448
    Helixi149 – 16719
    Turni168 – 1703
    Beta strandi172 – 1798
    Helixi186 – 20318
    Beta strandi208 – 2136
    Turni218 – 2214
    Helixi222 – 2254
    Beta strandi230 – 2367
    Helixi242 – 2498
    Beta strandi256 – 2605
    Helixi261 – 2644
    Helixi273 – 29220

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2IQTX-ray2.46A1-293[»]
    ProteinModelPortaliP60053.
    SMRiP60053. Positions 1-293.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP60053.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the class I fructose-bisphosphate aldolase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG3588.
    KOiK01623.
    OMAiANCARAK.
    OrthoDBiEOG6M6JJT.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00729. FBP_aldolase_1.
    InterProiIPR013785. Aldolase_TIM.
    IPR000741. FBA_I.
    IPR023014. FBA_I_Gram+-type.
    [Graphical view]
    PfamiPF00274. Glycolytic. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P60053-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNKEQLQQMR QAPGFVGALD QSGGSTPKAL KAYGIQPDAY QSEEEMFDLI    50
    HQMRTRMITS PAFATGKIIG VILFERTMRG KIEGMPTADF LWEKRHIVPF 100
    LKVDKGLQDE ANGVQLMKPF PELGKLCEEA VGYHVFGTKM RSVIKQANEQ 150
    GIRDIVEQQF QWGKEILSHG LVPILEPEVD IHCPEKAKAE EILKRELLAQ 200
    LDKMTEPVML KITIPTVDNF YKEIIEHPMM LRVVALSGGY SREQANELLS 250
    RNHGVIASFS RALVEGLSAR QTDAEFNAML EASIEDVYQA SIK 293
    Length:293
    Mass (Da):32,987
    Last modified:November 21, 2003 - v1
    Checksum:i8BF85BFF649DCE93
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015924 Genomic DNA. Translation: AAQ66757.1.
    RefSeqiNP_905858.1. NC_002950.2.
    WP_005875392.1. NC_002950.2.

    Genome annotation databases

    EnsemblBacteriaiAAQ66757; AAQ66757; PG_1755.
    GeneIDi2552379.
    KEGGipgi:PG1755.
    PATRICi22980496. VBIPorGin134034_1622.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015924 Genomic DNA. Translation: AAQ66757.1 .
    RefSeqi NP_905858.1. NC_002950.2.
    WP_005875392.1. NC_002950.2.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2IQT X-ray 2.46 A 1-293 [» ]
    ProteinModelPortali P60053.
    SMRi P60053. Positions 1-293.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 242619.PG1755.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAQ66757 ; AAQ66757 ; PG_1755 .
    GeneIDi 2552379.
    KEGGi pgi:PG1755.
    PATRICi 22980496. VBIPorGin134034_1622.

    Phylogenomic databases

    eggNOGi COG3588.
    KOi K01623.
    OMAi ANCARAK.
    OrthoDBi EOG6M6JJT.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00183 .
    BioCyci PGIN242619:GHX8-1583-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei P60053.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00729. FBP_aldolase_1.
    InterProi IPR013785. Aldolase_TIM.
    IPR000741. FBA_I.
    IPR023014. FBA_I_Gram+-type.
    [Graphical view ]
    Pfami PF00274. Glycolytic. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-308 / W83.

    Entry informationi

    Entry nameiALF1_PORGI
    AccessioniPrimary (citable) accession number: P60053
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 21, 2003
    Last sequence update: November 21, 2003
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3