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Protein

Transcription elongation factor 1 homolog

Gene

Elof1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi26ZincCombined sources1
Metal bindingi29ZincCombined sources1
Metal bindingi50ZincCombined sources1
Metal bindingi53ZincCombined sources1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription elongation factor 1 homolog
Gene namesi
Name:Elof1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:1913376 Elof1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001209421 – 83Transcription elongation factor 1 homologAdd BLAST83

Proteomic databases

EPDiP60003
PaxDbiP60003
PeptideAtlasiP60003
PRIDEiP60003

PTM databases

PhosphoSitePlusiP60003

Expressioni

Gene expression databases

BgeeiENSMUSG00000013822
CleanExiMM_ELOF1
ExpressionAtlasiP60003 baseline and differential
GenevisibleiP60003 MM

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiP60003, 1 interactor
MINTiP60003
STRINGi10090.ENSMUSP00000013966

Structurei

Secondary structure

183
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Turni27 – 29Combined sources3
Beta strandi35 – 40Combined sources6
Turni41 – 44Combined sources4
Beta strandi45 – 53Combined sources9
Beta strandi56 – 60Combined sources5
Helixi69 – 79Combined sources11

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1WIINMR-A8-79[»]
ProteinModelPortaliP60003
SMRiP60003
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP60003

Family & Domainsi

Sequence similaritiesi

Belongs to the ELOF1 family.Curated

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG3214 Eukaryota
COG4888 LUCA
GeneTreeiENSGT00390000000053
HOVERGENiHBG024628
InParanoidiP60003
OMAiFTCLFCH
OrthoDBiEOG091G14AQ
PhylomeDBiP60003
TreeFamiTF313731

Family and domain databases

Gene3Di2.20.25.190, 1 hit
InterProiView protein in InterPro
IPR007808 Elf1
IPR038567 T_Elf1_sf
PANTHERiPTHR20934 PTHR20934, 1 hit
PfamiView protein in Pfam
PF05129 Elf1, 1 hit

Sequencei

Sequence statusi: Complete.

P60003-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRRKSKRKP PPKKKMTGTL ETQFTCPFCN HEKSCDVKMD RARNTGVISC
60 70 80
TVCLEEFQTP ITYLSEPVDV YSDWIDACEA ANQ
Length:83
Mass (Da):9,462
Last modified:November 14, 2003 - v1
Checksum:i77F11EFBEC72AC6F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC019870 mRNA Translation: AAH19870.3
BC024488 mRNA Translation: AAH24488.3
BC056225 mRNA Translation: AAH56225.1
CCDSiCCDS40559.1
RefSeqiNP_740747.1, NM_170777.3
XP_017168995.1, XM_017313506.1
XP_017168996.1, XM_017313507.1
XP_017168997.1, XM_017313508.1
UniGeneiMm.29801

Genome annotation databases

EnsembliENSMUST00000013966; ENSMUSP00000013966; ENSMUSG00000013822
ENSMUST00000166335; ENSMUSP00000128173; ENSMUSG00000013822
ENSMUST00000213233; ENSMUSP00000150169; ENSMUSG00000013822
ENSMUST00000214394; ENSMUSP00000150536; ENSMUSG00000013822
ENSMUST00000216837; ENSMUSP00000149885; ENSMUSG00000013822
GeneIDi66126
KEGGimmu:66126
UCSCiuc009onw.1 mouse

Similar proteinsi

Entry informationi

Entry nameiELOF1_MOUSE
AccessioniPrimary (citable) accession number: P60003
Secondary accession number(s): Q8R1J7, Q96II4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 14, 2003
Last sequence update: November 14, 2003
Last modified: March 28, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

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