Reviewed, UniProtKB/Swiss-Prot P59960 (DIPZ_MYCBO)

Names and origin

Protein names

Recommended name:
    Protein dipZ

Gene names

Name:	dipZ
Ordered Locus Names:	Mb2899

Organism

Mycobacterium bovis [Complete proteome] [HAMAP]

Taxonomic identifier

1765 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	695 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Predicted.

General annotation (Comments)

Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Sequence similarities	Contains 1 thioredoxin domain.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell redox homeostasis Inferred from electronic annotation. Source: InterPro cytochrome complex assembly Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	antioxidant activity Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 695	695	Protein dipZ		PRO_0000079910
Regions
	Transmembrane	123 – 143	21	Potential
	Transmembrane	179 – 199	21	Potential
	Transmembrane	205 – 225	21	Potential
	Transmembrane	254 – 274	21	Potential
	Transmembrane	285 – 305	21	Potential
	Transmembrane	325 – 345	21	Potential
	Domain	394 – 542	149	Thioredoxin

Sequences

	Sequence		Length	Mass (Da)
	P59960-1 [UniParc]. Last modified October 31, 2003. Version 1. Checksum: 16B8ADEE33FF73DA	FASTA	695	74,120
	10 20 30 40 50 60 MVESRRAAAA ASAYASRCGI APATSQRSLA TPPTISVPSG EGRCRCHVAR GAGRDPRRRL 70 80 90 100 110 120 RRRRWCGRCG YHSHLTGGEF DVNRLCQQRS RERSCQLVAV PADPRPKRQR ITDVLTLALV 130 140 150 160 170 180 GFLGGLITGI SPCILPVLPV IFFSGAQSVD AAQVAKPEGA VAVRRKRALS ATLRPYRVIG 190 200 210 220 230 240 GLVLSFGMVT LLGSALLSVL HLPQDAIRWA ALVALVAIGA GLIFPRFEQL LEKPFSRIPQ 250 260 270 280 290 300 KQIVTRSNGF GLGLALGVLY VPCAGPILAA IVVAGATATI GLGTVVLTAT FALGAALPLL 310 320 330 340 350 360 FFALAGQRIA ERVGAFRRRQ REIRIATGSV TILLAVALVF DLPAALQRAI PDYTASLQQQ 370 380 390 400 410 420 ISTGTEIREQ LNLGGIVNAQ NAQLSNCSDG AAQLESCGTA PDLKGITGWL NTPGNKPIDL 430 440 450 460 470 480 KSLRGKVVLI DFWAYSCINC QRAIPHVVGW YQAYKDSGLA VIGVHTPEYA FEKVPGNVAK 490 500 510 520 530 540 GAANLGISYP IALDNNYATW TNYRNRYWPA EYLIDATGTV RHIKFGEGDY NVTETLVRQL 550 560 570 580 590 600 LNDAKPGVKL PQPSSTTTPD LTPRAALTPE TYFGVGKVVN YGGGGAYDEG SAVFDYPPSL 610 620 630 640 650 660 AANSFALRGR WALDYQGATS DGNDAAIKLN YHAKDVYIVV GGTGTLTVVR DGKPATLPIS 670 680 690 GPPTTHQVVA GDRLASETLE VRPSKGLQVF SFTYG

References

[1]

"The complete genome sequence of Mycobacterium bovis." Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M., Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B., Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J. , Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G. Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003) [PubMed: 12788972] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-935 / AF2122/97.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX248344 Genomic DNA. Translation: CAD96586.1.
RefSeq	NP_856544.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1092209.
GenomeReviews	Gene locus Mb2899 in contig BX248333_GR.
KEGG	mbo:Mb2899.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P59960.
OMA	P59960. QAYAFTF.
Family and domain databases
InterPro	IPR000866. Alkyl_hydroperoxide_Rdtase. IPR003834. Cyt_c_assmbl_TM. IPR017936. Thioredoxin-like. IPR012335. Thioredoxin_fold. [Graphical view]
Gene3D	G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
Pfam	PF00578. AhpC-TSA. 1 hit. PF02683. DsbD. 1 hit. [Graphical view]
ProDom	PD003679. Thioredoxin_like. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS51352. THIOREDOXIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DIPZ_MYCBO

Accession

Primary (citable) accession number: P59960

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2003
Last sequence update:	October 31, 2003
Last modified:	June 16, 2009
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)