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P59915 (HAGA1_PORGI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Hemagglutinin A
Gene names
Name:hagA
Ordered Locus Names:PG_1837
OrganismPorphyromonas gingivalis (strain ATCC BAA-308 / W83) [Complete proteome] [HAMAP]
Taxonomic identifier242619 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Porphyromonadaceae › Porphyromonas ›

Protein attributes

Sequence length2164 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Agglutinates erythrocytes By similarity.

Sequence similarities

Belongs to the peptidase C25 family.

Sequence caution

The sequence AAQ66831.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processVirulence
   DomainRepeat
Signal
   Molecular functionHemagglutinin
Hydrolase
Protease
Thiol protease
   Technical term3D-structure
Complete proteome
Gene Ontology (GO)
   Biological_processpathogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

proteolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functioncysteine-type peptidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2525 Potential
Chain26 – 21642139Hemagglutinin A
PRO_0000026537

Regions

Region26 – 539514Peptidase C25-like 1
Region540 – 991452Peptidase C25-like 2
Region992 – 1443452Peptidase C25-like 3

Secondary structure

1 ........................... 2164
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P59915 [UniParc].

Last modified October 10, 2003. Version 1.
Checksum: 6DFAB22832586C63

FASTA2,164233,389
        10         20         30         40         50         60 
MRKLNSLFSL AVLLSLLCWG QTAAAQGGPK TAPSVTHQAV QKGIRTSKAK DLRDPIPAGM 

        70         80         90        100        110        120 
ARIILEAHDV WEDGTGYQML WDADHNQYGA SIPEESFWFA NGTIPAGLYD PFEYKVPVNA 

       130        140        150        160        170        180 
DASFSPTNFV LDGTASADIP AGTYDYVIIN PNPGIIYIVG EGVSKGNDYV VEAGKTYHFT 

       190        200        210        220        230        240 
VQRQGPGDAA SVVVTGEGGN EFAPVQNLQW SVSGQTVTLT WQAPASDKRT YVLNESFDTQ 

       250        260        270        280        290        300 
TLPNGWTMID ADGDGHNWLS TINVYNTATH TGDGAMFSKS WTASSGAKID LSPDNYLVTP 

       310        320        330        340        350        360 
KFTVPENGKL SYWVSSQEPW TNEHYGVFLS TTGNEAANFT IKLLEETLGS GKPAPMNLVK 

       370        380        390        400        410        420 
SEGVKAPAPY QERTIDLSAY AGQQVYLAFR HFGCTGIFRL YLDDVAVSGE GSSNDYTYTV 

       430        440        450        460        470        480 
YRDNVVIAQN LTATTFNQEN VAPGQYNYCV EVKYTAGVSP KVCKDVTVEG SNEFAPVQNL 

       490        500        510        520        530        540 
TGSAVGQKVT LKWDAPNGTP NPNPGTTTLS ESFENGIPAS WKTIDADGDG NNWTTTPPPG 

       550        560        570        580        590        600 
GSSFAGHNSA ICVSSASYIN FEGPQNPDNY LVTPELSLPN GGTLTFWVCA QDANYASEHY 

       610        620        630        640        650        660 
AVYASSTGND ASNFANALLE EVLTAKTVVT APEAIRGTRV QGTWYQKTVQ LPAGTKYVAF 

       670        680        690        700        710        720 
RHFGCTDFFW INLDDVEIKA NGKRADFTET FESSTHGEAP AEWTTIDADG DGQGWLCLSS 

       730        740        750        760        770        780 
GQLGWLTAHG GTNVVASFSW NGMALNPDNY LISKDVTGAT KVKYYYAVND GFPGDHYAVM 

       790        800        810        820        830        840 
ISKTGTNAGD FTVVFEETPN GINKGGARFG LSTEANGAKP QSVWIERTVD LPAGTKYVAF 

       850        860        870        880        890        900 
RHYNCSDLNY ILLDDIQFTM GGSPTPTDYT YTVYRDGTKI KEGLTETTFE EDGVATGNHE 

       910        920        930        940        950        960 
YCVEVKYTAG VSPKECVNVT VDPVQFNPVQ NLTGSAVGQK VTLKWDAPNG TPNPNPGTTT 

       970        980        990       1000       1010       1020 
LSESFENGIP ASWKTIDADG DGNNWTTTPP PGGTSFAGHN SAICVSSASY INFEGPQNPD 

      1030       1040       1050       1060       1070       1080 
NYLVTPELSL PNGGTLTFWV CAQDANYASE HYAVYASSTG NDASNFANAL LEEVLTAKTV 

      1090       1100       1110       1120       1130       1140 
VTAPEAIRGT RVQGTWYQKT VQLPAGTKYV AFRHFGCTDF FWINLDDVEI KANGKRADFT 

      1150       1160       1170       1180       1190       1200 
ETFESSTHGE APAEWTTIDA DGDGQGWLCL SSGQLDWLTA HGGTNVVASF SWNGMALNPD 

      1210       1220       1230       1240       1250       1260 
NYLISKDVTG ATKVKYYYAV NDGFPGDHYA VMISKTGTNA GDFTVVFEET PNGINKGGAR 

      1270       1280       1290       1300       1310       1320 
FGLSTEANGA KPQSVWIERT VDLPAGTKYV AFRHYNCSDL NYILLDDIQF TMGGSPTPTD 

      1330       1340       1350       1360       1370       1380 
YTYTVYRDGT KIKEGLTETT FEEDGVATGN HEYCVEVKYT AGVSPKECVN VTVDPVQFNP 

      1390       1400       1410       1420       1430       1440 
VQNLTGSAVG QKVTLKWDAP NGTPNPNPGT TTLSESFENG IPASWKTIDA DGDGNNWTTT 

      1450       1460       1470       1480       1490       1500 
PPPGGTSFAG HNSAICVSSA SYINFEGPQN PDNYLVTPEL SLPNGGTLTF WVCAQDANYA 

      1510       1520       1530       1540       1550       1560 
SEHYAVYASS TGNDASNFAN ALLEEVLTAK TVVTAPEAIR GTRVQGTWYQ KTVQLPAGTK 

      1570       1580       1590       1600       1610       1620 
YVAFRHFGCT DFFWINLDDV EIKANGKRAD FTETFESSTH GEAPAEWTTI DADGDGQGWL 

      1630       1640       1650       1660       1670       1680 
CLSSGQLGWL TAHGGTNVVA SFSWNGMALN PDNYLISKDV TGATKVKYYY AVNDGFPGDH 

      1690       1700       1710       1720       1730       1740 
YAVMISKTGT NAGDFTVVFE ETPNGINKGG ARFGLSTEAN GAKPQSVWIE RTVDLPAGTK 

      1750       1760       1770       1780       1790       1800 
YVAFRHYNCS DLNYILLDDI QFTMGGSPTP TDYTYTVYRD GTKIKEGLTE TTFEEDGVAT 

      1810       1820       1830       1840       1850       1860 
GNHEYCVEVK YTAGVSPKEC VNVTINPTQF NPVQNLTAEQ APNSMDAILK WNAPASKRAE 

      1870       1880       1890       1900       1910       1920 
VLNEDFENGI PASWKTIDAD GDGNNWTTTP PPGGSSFAGH NSAICVSSAS YINFEGPQNP 

      1930       1940       1950       1960       1970       1980 
DNYLVTPELS LPGGGTLTFW VCAQDANYAS EHYAVYASST GNDASNFANA LLEEVLTAKT 

      1990       2000       2010       2020       2030       2040 
VVTAPEAIRG TRVQGTWYQK TVQLPAGTKY VAFRHFGCTD FFWINLDDVV ITSGNAPSYT 

      2050       2060       2070       2080       2090       2100 
YTIYRNNTQI ASGVTETTYR DPDLATGFYT YGVKVVYPNG ESAIETATLN ITSLADVTAQ 

      2110       2120       2130       2140       2150       2160 
KPYTLTVVGK TITVTCQGEA MIYDMNGRRL AAGRNTVVYT AQGGHYAVMV VVDGKSYVEK 


LAVK

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE015924 Genomic DNA. Translation: AAQ66831.1. Different initiation.
RefSeqNP_905932.1. NC_002950.2.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3KM5X-ray1.40A/B1137-1314[»]
ModBaseSearch...

Protein-protein interaction databases

STRING242619.PG1837.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAQ66831; AAQ66831; PG_1837.
GeneID2551934.
KEGGpgi:PG1837.
PATRIC22980654. VBIPorGin134034_1698.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAAFRHFGC.
ProtClustDBCLSK2306121.

Enzyme and pathway databases

BioCycPGIN242619:GHX8-1610-MONOMER.

Family and domain databases

InterProIPR011628. Cleaved_adhesin.
IPR003961. Fibronectin_type3.
IPR018832. Pept_C25_gingipain_C.
[Graphical view]
PfamPF07675. Cleaved_Adhesin. 8 hits.
PF10365. DUF2436. 1 hit.
[Graphical view]
SMARTSM00060. FN3. 5 hits.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP59915.

Entry information

Entry nameHAGA1_PORGI
AccessionPrimary (citable) accession number: P59915
Entry history
Integrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: October 10, 2003
Last modified: May 1, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Peptidase families

Classification of peptidase families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents