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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Synechococcus sp. (strain WH8102)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei41NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:SYNW0544
OrganismiSynechococcus sp. (strain WH8102)
Taxonomic identifieri84588 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesSynechococcaceaeSynechococcus
Proteomesi
  • UP000001422 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001219271 – 291tRNA pseudouridine synthase BAdd BLAST291

Interactioni

Protein-protein interaction databases

STRINGi84588.SYNW0544

Structurei

3D structure databases

ProteinModelPortaliP59884
SMRiP59884
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T Bacteria
COG0130 LUCA
HOGENOMiHOG000231225
KOiK03177
OMAiVDCSKGT
OrthoDBiPOG091H02G9

Family and domain databases

HAMAPiMF_01080 TruB_bact, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR002501 PsdUridine_synth_N
IPR014780 tRNA_psdUridine_synth_TruB
IPR032819 TruB_C
PANTHERiPTHR13767 PTHR13767, 1 hit
PfamiView protein in Pfam
PF16198 TruB_C_2, 1 hit
PF01509 TruB_N, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00431 TruB, 1 hit

Sequencei

Sequence statusi: Complete.

P59884-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGPFGFVVI DKPAGHTSHS CVSRLRRCYG LKRVGHGGTL DPAVTGVLPI
60 70 80 90 100
ALGPATRLLP YLPGDKTYRG VIQLGSITSS DDLEGELLRQ APWPDLQPEE
110 120 130 140 150
LEVALAPFRG PIQQRPPQVS AVHVDGERAH ARARRGEQMV LPPRPVTIHR
160 170 180 190 200
LQLLHWDPNQ GQLTLEVHCS AGTYIRSLAR DLGEQLGCGG CLAQLRRTQA
210 220 230 240 250
LGFLESQAQA LPEADATPPP PLSPLLALEH LPRRQLTDSE EADWRCGRRL
260 270 280 290
SLDPGPGDAV VVCNADGSMA GIGLRQEDDQ LQPKVVFDAS G
Length:291
Mass (Da):31,448
Last modified:September 26, 2003 - v1
Checksum:i71BD68FA3DAA35E3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX569690 Genomic DNA Translation: CAE07059.1

Genome annotation databases

EnsemblBacteriaiCAE07059; CAE07059; SYNW0544
KEGGisyw:SYNW0544

Similar proteinsi

Entry informationi

Entry nameiTRUB_SYNPX
AccessioniPrimary (citable) accession number: P59884
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2003
Last sequence update: September 26, 2003
Last modified: March 28, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health