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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei49NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:BR2167, BS1330_I2161
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000007104 Componenti: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001218051 – 324tRNA pseudouridine synthase BAdd BLAST324

Structurei

3D structure databases

ProteinModelPortaliP59876
SMRiP59876
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000231225
KOiK03177
OMAiVDCSKGT

Family and domain databases

HAMAPiMF_01080 TruB_bact, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR002501 PsdUridine_synth_N
IPR014780 tRNA_psdUridine_synth_TruB
IPR015240 tRNA_sdUridine_synth_fam1_C
IPR032819 TruB_C
PANTHERiPTHR13767 PTHR13767, 1 hit
PfamiView protein in Pfam
PF09157 TruB-C_2, 1 hit
PF16198 TruB_C_2, 1 hit
PF01509 TruB_N, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00431 TruB, 1 hit

Sequencei

Sequence statusi: Complete.

P59876-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARRGKKKGR PISGWVIFDK PKGMGSTEAV SKIKWLFSAE KAGHAGTLDP
60 70 80 90 100
LASGMLPIAL GEATKTVPYV MDGTKVYRFT VTWGEERSTD DLEGQPTKTS
110 120 130 140 150
DKRPSREEVE ALLPDYTGVI SQVPPQFSAI KIDGERAYDL AREGETVEIP
160 170 180 190 200
AREVEIDRLE IVGFPDADRT EFEVECSKGT YVRSLARDMG RDLGCYGHIS
210 220 230 240 250
DLRRVEVAPF TDEDMVTLAK LEAVWPPLPP KDEDGNVIEP APRRDFSALD
260 270 280 290 300
ALVIDTGAAL DCLPQVPLSD DQAQRVRLGN PVILRGRDAP LEADEACVTT
310 320
RGKLLAIGYI EHGQFKPKRV FTAG
Length:324
Mass (Da):35,595
Last modified:September 26, 2003 - v1
Checksum:i850AF77186777988
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA Translation: AAT34907.1
CP002997 Genomic DNA Translation: AEM19474.1
RefSeqiWP_002965229.1, NZ_KN046804.1

Genome annotation databases

EnsemblBacteriaiAAT34907; AAT34907; BR2167
AEM19474; AEM19474; BS1330_I2161
KEGGibms:BR2167
bsi:BS1330_I2161
PATRICifig|204722.21.peg.643

Similar proteinsi

Entry informationi

Entry nameiTRUB_BRUSU
AccessioniPrimary (citable) accession number: P59876
Secondary accession number(s): G0K9J3, Q6I817
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2003
Last sequence update: September 26, 2003
Last modified: March 28, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health