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Protein

Mitochondrial import inner membrane translocase subunit tim17

Gene

tim17

Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial import inner membrane translocase subunit tim17
Gene namesi
Name:tim17
ORF Names:NCU05623
OrganismiNeurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Taxonomic identifieri367110 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesSordariaceaeNeurospora
Proteomesi
  • UP000001805 Componenti: Chromosome 5, Linkage Group VI

Organism-specific databases

EuPathDBiFungiDB:NCU05623.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei10 – 30HelicalSequence analysisAdd BLAST21
Transmembranei57 – 77HelicalSequence analysisAdd BLAST21
Transmembranei87 – 107HelicalSequence analysisAdd BLAST21
Transmembranei112 – 132HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002102941 – 155Mitochondrial import inner membrane translocase subunit tim17Add BLAST155

Interactioni

Subunit structurei

Component of the TIM23 complex, at least composed of tim23, tim17, tim50 and tim21. The complex interacts with the tim44 component of the PAM complex (By similarity).By similarity

Family & Domainsi

Sequence similaritiesi

Belongs to the Tim17/Tim22/Tim23 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000183190.
InParanoidiP59670.
KOiK17795.
OMAiWKHTRNS.
OrthoDBiEOG092C5C6F.

Family and domain databases

InterProiIPR005678. Tim17.
IPR003397. Tim17/Tim22/Tim23/PMP24.
[Graphical view]
PANTHERiPTHR10485. PTHR10485. 1 hit.
PfamiPF02466. Tim17. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P59670-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDHTRDPCPW VILNDFGGAF AMGAIGGTIW HGIKGFRNSP YGERRIGAIT
60 70 80 90 100
AIKMRAPALG GNFGVWGGLF STFDCAIKGL RNHKEDPWNS ILAGFFTGGA
110 120 130 140 150
LAVRGGYKAA RNGAIGCAVL LAVIEGVGIG FQKMLAGATK LEAPAPPPSN

EKVLA
Length:155
Mass (Da):16,184
Last modified:May 9, 2003 - v1
Checksum:i78F48D2F3720E5FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY212506 mRNA. Translation: AAO72334.1.
CM002241 Genomic DNA. Translation: EAA30931.1.
RefSeqiXP_960167.1. XM_955074.2.

Genome annotation databases

EnsemblFungiiEAA30931; EAA30931; NCU05623.
GeneIDi3876316.
KEGGincr:NCU05623.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY212506 mRNA. Translation: AAO72334.1.
CM002241 Genomic DNA. Translation: EAA30931.1.
RefSeqiXP_960167.1. XM_955074.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEAA30931; EAA30931; NCU05623.
GeneIDi3876316.
KEGGincr:NCU05623.

Organism-specific databases

EuPathDBiFungiDB:NCU05623.

Phylogenomic databases

HOGENOMiHOG000183190.
InParanoidiP59670.
KOiK17795.
OMAiWKHTRNS.
OrthoDBiEOG092C5C6F.

Family and domain databases

InterProiIPR005678. Tim17.
IPR003397. Tim17/Tim22/Tim23/PMP24.
[Graphical view]
PANTHERiPTHR10485. PTHR10485. 1 hit.
PfamiPF02466. Tim17. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTIM17_NEUCR
AccessioniPrimary (citable) accession number: P59670
Secondary accession number(s): Q7S5Y3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 9, 2003
Last sequence update: May 9, 2003
Last modified: November 2, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.