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Protein

FXYD domain-containing ion transport regulator 7

Gene

Fxyd7

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • ATPase binding Source: RGD
  • ion channel activity Source: InterPro
  • sodium channel regulator activity Source: GO_Central

GO - Biological processi

Keywordsi

Molecular functionIon channel
Biological processIon transport, Transport

Enzyme and pathway databases

ReactomeiR-RNO-5578775. Ion homeostasis.
R-RNO-936837. Ion transport by P-type ATPases.

Names & Taxonomyi

Protein namesi
Recommended name:
FXYD domain-containing ion transport regulator 7
Gene namesi
Name:Fxyd7
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi620830. Fxyd7.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei23 – 45HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

  • integral component of membrane Source: RGD
  • integral component of plasma membrane Source: GO_Central

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001481921 – 80FXYD domain-containing ion transport regulator 7Add BLAST80

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei73PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP59649.
PRIDEiP59649.

PTM databases

iPTMnetiP59649.
PhosphoSitePlusiP59649.

Expressioni

Gene expression databases

BgeeiENSRNOG00000021067.
GenevisibleiP59649. RN.

Interactioni

GO - Molecular functioni

  • ATPase binding Source: RGD

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000028603.

Structurei

3D structure databases

ProteinModelPortaliP59649.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FXYD family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J7S9. Eukaryota.
ENOG4111ECY. LUCA.
GeneTreeiENSGT00530000064670.
HOGENOMiHOG000112680.
HOVERGENiHBG051679.
InParanoidiP59649.
KOiK13364.
OMAiDYATVQT.
OrthoDBiEOG091G1A47.
PhylomeDBiP59649.
TreeFamiTF333443.

Family and domain databases

InterProiView protein in InterPro
IPR000272. Ion-transport_regulator_FXYD.
PfamiView protein in Pfam
PF02038. ATP1G1_PLM_MAT8. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD005989. PD005989. 1 hit.
PROSITEiView protein in PROSITE
PS01310. FXYD. 1 hit.

Sequencei

Sequence statusi: Complete.

P59649-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATPTQSPTN VPEETDPFFY DYATVQTVGM TLATIMFVLG IIIIISKKVK
60 70 80
CRKADSRSES PTCKSCKSEL PSSAPGGGGV
Length:80
Mass (Da):8,487
Last modified:April 30, 2003 - v1
Checksum:i135CEB3EC0D06CDC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AW914994 mRNA. No translation available.
RefSeqiNP_071291.1. NM_022008.1.
UniGeneiRn.33248.

Genome annotation databases

EnsembliENSRNOT00000028603; ENSRNOP00000028603; ENSRNOG00000021067.
GeneIDi63848.
KEGGirno:63848.
UCSCiRGD:620830. rat.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiFXYD7_RAT
AccessioniPrimary (citable) accession number: P59649
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 30, 2003
Last sequence update: April 30, 2003
Last modified: May 10, 2017
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families