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Protein

FXYD domain-containing ion transport regulator 7

Gene

Fxyd7

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • ATPase binding Source: RGD
  • ion channel activity Source: InterPro

GO - Biological processi

  • regulation of ion transport Source: RGD
Complete GO annotation...

Keywords - Molecular functioni

Ion channel

Keywords - Biological processi

Ion transport, Transport

Enzyme and pathway databases

ReactomeiR-RNO-5578775. Ion homeostasis.
R-RNO-936837. Ion transport by P-type ATPases.

Names & Taxonomyi

Protein namesi
Recommended name:
FXYD domain-containing ion transport regulator 7
Gene namesi
Name:Fxyd7
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi620830. Fxyd7.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei23 – 4523HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: RGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 8080FXYD domain-containing ion transport regulator 7PRO_0000148192Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei73 – 731PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP59649.
PRIDEiP59649.

PTM databases

iPTMnetiP59649.
PhosphoSiteiP59649.

Expressioni

Gene expression databases

GenevisibleiP59649. RN.

Interactioni

GO - Molecular functioni

  • ATPase binding Source: RGD

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000028603.

Structurei

3D structure databases

ProteinModelPortaliP59649.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FXYD family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J7S9. Eukaryota.
ENOG4111ECY. LUCA.
GeneTreeiENSGT00530000064670.
HOGENOMiHOG000112680.
HOVERGENiHBG051679.
InParanoidiP59649.
KOiK13364.
OMAiDYATVQT.
OrthoDBiEOG7JT6ZV.
PhylomeDBiP59649.
TreeFamiTF333443.

Family and domain databases

InterProiIPR000272. Ion-transport_regulator_FXYD.
[Graphical view]
PfamiPF02038. ATP1G1_PLM_MAT8. 1 hit.
[Graphical view]
ProDomiPD005989. PD005989. 1 hit.
[Graphical view] [Entries sharing at least one domain]
PROSITEiPS01310. FXYD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P59649-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATPTQSPTN VPEETDPFFY DYATVQTVGM TLATIMFVLG IIIIISKKVK
60 70 80
CRKADSRSES PTCKSCKSEL PSSAPGGGGV
Length:80
Mass (Da):8,487
Last modified:April 30, 2003 - v1
Checksum:i135CEB3EC0D06CDC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AW914994 mRNA. No translation available.
RefSeqiNP_071291.1. NM_022008.1.
UniGeneiRn.33248.

Genome annotation databases

EnsembliENSRNOT00000028603; ENSRNOP00000028603; ENSRNOG00000021067.
GeneIDi63848.
KEGGirno:63848.
UCSCiRGD:620830. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AW914994 mRNA. No translation available.
RefSeqiNP_071291.1. NM_022008.1.
UniGeneiRn.33248.

3D structure databases

ProteinModelPortaliP59649.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000028603.

PTM databases

iPTMnetiP59649.
PhosphoSiteiP59649.

Proteomic databases

PaxDbiP59649.
PRIDEiP59649.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000028603; ENSRNOP00000028603; ENSRNOG00000021067.
GeneIDi63848.
KEGGirno:63848.
UCSCiRGD:620830. rat.

Organism-specific databases

CTDi53822.
RGDi620830. Fxyd7.

Phylogenomic databases

eggNOGiENOG410J7S9. Eukaryota.
ENOG4111ECY. LUCA.
GeneTreeiENSGT00530000064670.
HOGENOMiHOG000112680.
HOVERGENiHBG051679.
InParanoidiP59649.
KOiK13364.
OMAiDYATVQT.
OrthoDBiEOG7JT6ZV.
PhylomeDBiP59649.
TreeFamiTF333443.

Enzyme and pathway databases

ReactomeiR-RNO-5578775. Ion homeostasis.
R-RNO-936837. Ion transport by P-type ATPases.

Miscellaneous databases

PROiP59649.

Gene expression databases

GenevisibleiP59649. RN.

Family and domain databases

InterProiIPR000272. Ion-transport_regulator_FXYD.
[Graphical view]
PfamiPF02038. ATP1G1_PLM_MAT8. 1 hit.
[Graphical view]
ProDomiPD005989. PD005989. 1 hit.
[Graphical view] [Entries sharing at least one domain]
PROSITEiPS01310. FXYD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Lee N.H., Glodek A., Chandra I., Mason T.M., Quackenbush J., Kerlavage A.R., Adams M.D.
    Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. Lubec G., Kang S.U., Lubec S.
    Submitted (SEP-2007) to UniProtKB
    Cited for: PROTEIN SEQUENCE OF 54-64 AND 68-80, IDENTIFICATION BY MASS SPECTROMETRY.
    Strain: Sprague-Dawley.
    Tissue: Brain.
  3. "The FXYD gene family of small ion transport regulators or channels: cDNA sequence, protein signature sequence, and expression."
    Sweadner K.J., Rael E.
    Genomics 68:41-56(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: RECONSTRUCTION FROM ESTS, CONCEPTUAL TRANSLATION.
  4. "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues."
    Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C., Olsen J.V.
    Nat. Commun. 3:876-876(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-73, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiFXYD7_RAT
AccessioniPrimary (citable) accession number: P59649
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 30, 2003
Last sequence update: April 30, 2003
Last modified: June 8, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.