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P59647

- FXYD5_RAT

UniProt

P59647 - FXYD5_RAT

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Protein

FXYD domain-containing ion transport regulator 5

Gene

Fxyd5

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ion channel activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ion channel

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
FXYD domain-containing ion transport regulator 5
Gene namesi
Name:Fxyd5
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 1

Organism-specific databases

RGDi620827. Fxyd5.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini22 – 146125ExtracellularSequence AnalysisAdd
BLAST
Transmembranei147 – 16418HelicalSequence AnalysisAdd
BLAST
Topological domaini165 – 17814CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121Sequence AnalysisAdd
BLAST
Chaini22 – 178157FXYD domain-containing ion transport regulator 5PRO_0000010371Add
BLAST

Proteomic databases

PaxDbiP59647.

Expressioni

Tissue specificityi

Spleen, lung, skeletal muscle, and testis.

Gene expression databases

GenevestigatoriP59647.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000028597.

Structurei

3D structure databases

ProteinModelPortaliP59647.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi88 – 13447Pro-richAdd
BLAST

Sequence similaritiesi

Belongs to the FXYD family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG43413.
GeneTreeiENSGT00410000026316.
HOGENOMiHOG000112679.
HOVERGENiHBG051678.
InParanoidiP59647.
KOiK13362.
OMAiFYYDEAT.
OrthoDBiEOG7MKW85.
PhylomeDBiP59647.
TreeFamiTF338182.

Family and domain databases

InterProiIPR000272. Ion-transport_regulator_FXYD.
[Graphical view]
PfamiPF02038. ATP1G1_PLM_MAT8. 1 hit.
[Graphical view]
ProDomiPD005989. PD005989. 1 hit.
[Graphical view] [Entries sharing at least one domain]
PROSITEiPS01310. FXYD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P59647-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSPPSQLCLL TIVALILPSE GQTPEKPRSS FTAHQSSVTT HVPVPDQTSP
60 70 80 90 100
GVQTTPPIWT SEAGEATGSQ TAAKTKTQQL TEMATANPVT DPGPLTSSEK
110 120 130 140 150
GTPALSRIKS PSPPKGYMPP SYIENPLDPN ENSPFYYDNT TLRKRGLLVA
160 170
AVLFITGIII LTSGKCRQFS QLCLNRHR
Length:178
Mass (Da):19,128
Last modified:September 5, 2006 - v2
Checksum:i99B30D88B928FF4E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC060571 mRNA. Translation: AAH60571.1.
RefSeqiNP_001257617.1. NM_001270688.1.
NP_001257618.1. NM_001270689.1.
NP_068709.2. NM_021909.2.
UniGeneiRn.234281.
Rn.24997.

Genome annotation databases

EnsembliENSRNOT00000028597; ENSRNOP00000028597; ENSRNOG00000021062.
GeneIDi60338.
KEGGirno:60338.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC060571 mRNA. Translation: AAH60571.1 .
RefSeqi NP_001257617.1. NM_001270688.1.
NP_001257618.1. NM_001270689.1.
NP_068709.2. NM_021909.2.
UniGenei Rn.234281.
Rn.24997.

3D structure databases

ProteinModelPortali P59647.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10116.ENSRNOP00000028597.

Proteomic databases

PaxDbi P59647.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000028597 ; ENSRNOP00000028597 ; ENSRNOG00000021062 .
GeneIDi 60338.
KEGGi rno:60338.

Organism-specific databases

CTDi 53827.
RGDi 620827. Fxyd5.

Phylogenomic databases

eggNOGi NOG43413.
GeneTreei ENSGT00410000026316.
HOGENOMi HOG000112679.
HOVERGENi HBG051678.
InParanoidi P59647.
KOi K13362.
OMAi FYYDEAT.
OrthoDBi EOG7MKW85.
PhylomeDBi P59647.
TreeFami TF338182.

Miscellaneous databases

PROi P59647.

Gene expression databases

Genevestigatori P59647.

Family and domain databases

InterProi IPR000272. Ion-transport_regulator_FXYD.
[Graphical view ]
Pfami PF02038. ATP1G1_PLM_MAT8. 1 hit.
[Graphical view ]
ProDomi PD005989. PD005989. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
PROSITEi PS01310. FXYD. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Pituitary.
  2. "The FXYD gene family of small ion transport regulators or channels: cDNA sequence, protein signature sequence, and expression."
    Sweadner K.J., Rael E.
    Genomics 68:41-56(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiFXYD5_RAT
AccessioniPrimary (citable) accession number: P59647
Secondary accession number(s): Q6P9W0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 30, 2003
Last sequence update: September 5, 2006
Last modified: October 1, 2014
This is version 77 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3