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Protein

FXYD domain-containing ion transport regulator 5

Gene

Fxyd5

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
FXYD domain-containing ion transport regulator 5
Gene namesi
Name:Fxyd5
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi620827 Fxyd5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini22 – 146ExtracellularSequence analysisAdd BLAST125
Transmembranei147 – 164HelicalSequence analysisAdd BLAST18
Topological domaini165 – 178CytoplasmicSequence analysisAdd BLAST14

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_000001037122 – 178FXYD domain-containing ion transport regulator 5Add BLAST157

Proteomic databases

PaxDbiP59647

Expressioni

Tissue specificityi

Spleen, lung, skeletal muscle, and testis.

Gene expression databases

BgeeiENSRNOG00000021062
GenevisibleiP59647 RN

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000028597

Structurei

3D structure databases

ProteinModelPortaliP59647
SMRiP59647
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi88 – 134Pro-richAdd BLAST47

Sequence similaritiesi

Belongs to the FXYD family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410JCU8 Eukaryota
ENOG4111E7R LUCA
GeneTreeiENSGT00410000026316
HOGENOMiHOG000112679
HOVERGENiHBG051678
InParanoidiP59647
KOiK13362
OMAiWPADETP
PhylomeDBiP59647
TreeFamiTF338182

Family and domain databases

InterProiView protein in InterPro
IPR000272 Ion-transport_regulator_FXYD
PfamiView protein in Pfam
PF02038 ATP1G1_PLM_MAT8, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD005989 PD005989, 1 hit
PROSITEiView protein in PROSITE
PS01310 FXYD, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P59647-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPPSQLCLL TIVALILPSE GQTPEKPRSS FTAHQSSVTT HVPVPDQTSP
60 70 80 90 100
GVQTTPPIWT SEAGEATGSQ TAAKTKTQQL TEMATANPVT DPGPLTSSEK
110 120 130 140 150
GTPALSRIKS PSPPKGYMPP SYIENPLDPN ENSPFYYDNT TLRKRGLLVA
160 170
AVLFITGIII LTSGKCRQFS QLCLNRHR
Length:178
Mass (Da):19,128
Last modified:September 5, 2006 - v2
Checksum:i99B30D88B928FF4E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC060571 mRNA Translation: AAH60571.1
RefSeqiNP_001257617.1, NM_001270688.1
NP_001257618.1, NM_001270689.1
NP_068709.2, NM_021909.2
UniGeneiRn.234281
Rn.24997

Genome annotation databases

EnsembliENSRNOT00000028597; ENSRNOP00000028597; ENSRNOG00000021062
ENSRNOT00000089474; ENSRNOP00000068919; ENSRNOG00000021062
GeneIDi60338
KEGGirno:60338

Similar proteinsi

Entry informationi

Entry nameiFXYD5_RAT
AccessioniPrimary (citable) accession number: P59647
Secondary accession number(s): Q6P9W0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 30, 2003
Last sequence update: September 5, 2006
Last modified: May 23, 2018
This is version 94 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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