Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Anti-sigma F factor

Gene

spoIIAB

Organism
Pasteuria penetrans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.UniRule annotation

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
Biological processSporulation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Anti-sigma F factorUniRule annotation (EC:2.7.11.1UniRule annotation)
Alternative name(s):
Stage II sporulation protein ABUniRule annotation
Gene namesi
Name:spoIIABUniRule annotation
OrganismiPasteuria penetrans
Taxonomic identifieri86005 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPasteuriaceaePasteuria

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002035681 – 150Anti-sigma F factorAdd BLAST150

Structurei

3D structure databases

ProteinModelPortaliP59624
SMRiP59624
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the anti-sigma-factor family.UniRule annotation

Family and domain databases

CDDicd00075 HATPase_c, 1 hit
Gene3Di3.30.565.10, 1 hit
HAMAPiMF_00637 Anti_sigma_F, 1 hit
InterProiView protein in InterPro
IPR010194 Anti-sigma_F
IPR003594 HATPase_C
IPR036890 HATPase_C_sf
PANTHERiPTHR35526:SF2 PTHR35526:SF2, 1 hit
PfamiView protein in Pfam
PF13581 HATPase_c_2, 1 hit
SMARTiView protein in SMART
SM00387 HATPase_c, 1 hit
SUPFAMiSSF55874 SSF55874, 1 hit
TIGRFAMsiTIGR01925 spIIAB, 1 hit

Sequencei

Sequence statusi: Complete.

P59624-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRNRMEMEF TSCSENEAFA RIAVAAFVAQ LDPTLEELTD IKTVVSEAVT
60 70 80 90 100
NAVIHAYGEC SEGMMVRVSV EIEDTQVAIT VTDRGVGIVD VEQARQPLYT
110 120 130 140 150
SRPEWERAGM GFSIMEHFMD QVRVRSTPGQ GTVVHMIKKL QASRNVAVVN
Length:150
Mass (Da):16,679
Last modified:April 23, 2003 - v1
Checksum:i71DA0E8A775E7F27
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF483656 Genomic DNA Translation: AAO63809.1

Similar proteinsi

Entry informationi

Entry nameiSP2AB_PASPE
AccessioniPrimary (citable) accession number: P59624
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 23, 2003
Last sequence update: April 23, 2003
Last modified: May 23, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health