P59580 (KCY_BUCBP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytidylate kinase
Short name=CK
EC=2.7.4.25

Alternative name(s):
Cytidine monophosphate kinase
Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	bbp_287

Organism

Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp) [Complete proteome] [HAMAP]

Taxonomic identifier

224915 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	230 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238
Subcellular location	Cytoplasm By similarity HAMAP MF_00238.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cytidylate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 230	230	Cytidylate kinase HAMAP MF_00238		PRO_0000131893
Regions
	Nucleotide binding	14 – 22	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	P59580 [UniParc]. Last modified April 11, 2003. Version 1. Checksum: BDE8D098E74CAEB5	FASTA	230	26,787
	10 20 30 40 50 60 MSFKNLVPVI TIDGPSGVGK SSVCKVISKK LQWNVLESGW IYRVLAFIIF KNNVCFSSRN 70 80 90 100 110 120 LNILFKNINL HDFIQRINFK NYVISQSLFT NISQEYIGNL ASRLACIPYI RHFLLFQQRS 130 140 150 160 170 180 FRKFPGLIAN GRDMGTVVFP DAIIKFFLIS DFKTRVARRC LEYEKKGINS CNYKKIFYDM 190 200 210 220 230 KTRDQRDHNR KISPLIPAKN AILIDSTYMS LKQVSNVLLS YILKMQKFKL

References

[1]

"Reductive genome evolution in Buchnera aphidicola." van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F., Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J., Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A. Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003) [PubMed: 12522265] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bp.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016826 Genomic DNA. Translation: AAO27012.1.
RefSeq	NP_777907.1. NC_004545.1.
3D structure databases
ProteinModelPortal	P59580.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBUCT00000002673; EBBUCP00000002497; EBBUCG00000002673.
GeneID	1058251.
GenomeReviews	Gene locus bbp_287 in contig AE016826_GR.
KEGG	bab:bbp287.
PATRIC	21245361. VBIBucAph80364_0283.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG354377.
OMA	IANILRM.
PhylomeDB	P59580.
Enzyme and pathway databases
BioCyc	BAPH224915:BBP_287-MONOMER.
Family and domain databases
HAMAP	MF_00238. Cytidyl_kinase_type1. [Tree]
InterPro	IPR003136. Cytidylate_kin. IPR011994. Cytidylate_kinase_dom. [Graphical view]
KO	K00945.
PANTHER	PTHR21299:SF2. Cytidylate_kin. 1 hit.
Pfam	PF02224. Cytidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR00017. Cmk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_BUCBP

Accession

Primary (citable) accession number: P59580

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 11, 2003
Last sequence update:	April 11, 2003
Last modified:	January 25, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program