P59464 (DCD_BUCBP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	bbp_102

Organism

Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp) [Complete proteome] [HAMAP]

Taxonomic identifier

224915 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera › Buchnera aphidicola › Buchnera aphidicola (Baizongia pistaciae)

Protein attributes

Sequence length	193 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 193	193	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_0000155971

Sequences

	Sequence		Length	Mass (Da)
	P59464 [UniParc]. Last modified March 28, 2003. Version 1. Checksum: AF9160FE0C47AF79	FASTA	193	22,111
	10 20 30 40 50 60 MRLSDRDIEL WIKNKKLVIE PIPNKELIHG VTIDVRLGNE FYTFCNKFNK NIDLSKSRNE 70 80 90 100 110 120 ISKILKKVMN KKHIIPNDHV FLLKPGMFVL AITLEKIFLP NNLVGWLDGR SSLARLGLMI 130 140 150 160 170 180 HATSHRIDPG WGGNIVLEFF NSSNMILSLC PGMLIAAVSF EILSSPSIRP YNIRKNAKYF 190 NQSEVTFSRI DQD

References

[1]

"Reductive genome evolution in Buchnera aphidicola." van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F., Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J., Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A. Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bp.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016826 Genomic DNA. Translation: AAO26837.1.
RefSeq	NP_777732.1. NC_004545.1.
3D structure databases
ProteinModelPortal	P59464.
SMR	P59464. Positions 1-193.
ModBase	Search...
Protein-protein interaction databases
STRING	224915.bbp102.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAO26837; AAO26837; bbp_102.
GeneID	1058552.
KEGG	bab:bbp102.
PATRIC	21244983. VBIBucAph80364_0099.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
KO	K01494.
OMA	RQDAKYK.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	BAPH224915:GJ9D-102-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_BUCBP

Accession

Primary (citable) accession number: P59464

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 28, 2003
Last sequence update:	March 28, 2003
Last modified:	May 1, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program