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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. Glyceraldehyde-3-phosphate dehydrogenase (gapA)
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA)
  4. Enolase (eno)
  5. Pyruvate kinase (pykA)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei36SubstrateUniRule annotation1
Binding sitei114SubstrateUniRule annotation1
Binding sitei147SubstrateUniRule annotation1
Binding sitei198ATPUniRule annotation1
Binding sitei314ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi340 – 343ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processGlycolysis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBAPH224915:G1G09-403-MONOMER
UniPathwayiUPA00109; UER00185

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:bbp_400
OrganismiBuchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Taxonomic identifieri224915 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeBuchnera
Proteomesi

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001459201 – 393Phosphoglycerate kinaseAdd BLAST393

Proteomic databases

PRIDEiP59461

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi224915.bbp400

Structurei

3D structure databases

ProteinModelPortaliP59461
SMRiP59461
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni21 – 23Substrate bindingUniRule annotation3
Regioni59 – 62Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105BZA Bacteria
COG0126 LUCA
KOiK00927
OMAiDMIFDIG
OrthoDBiPOG091H00YN

Family and domain databases

Gene3Di3.40.50.1260, 3 hits
HAMAPiMF_00145 Phosphoglyc_kinase, 1 hit
InterProiView protein in InterPro
IPR001576 Phosphoglycerate_kinase
IPR015911 Phosphoglycerate_kinase_CS
IPR015824 Phosphoglycerate_kinase_N
IPR036043 Phosphoglycerate_kinase_sf
PANTHERiPTHR11406 PTHR11406, 1 hit
PfamiView protein in Pfam
PF00162 PGK, 1 hit
PIRSFiPIRSF000724 Pgk, 1 hit
PRINTSiPR00477 PHGLYCKINASE
SUPFAMiSSF53748 SSF53748, 1 hit
PROSITEiView protein in PROSITE
PS00111 PGLYCERATE_KINASE, 1 hit

Sequencei

Sequence statusi: Complete.

P59461-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIIKITDLN LLNKKVLIRS DLNVPIKNNK ISSYARIHAS LPTIKFALKN
60 70 80 90 100
LAKVIVTSHL GRPTEGIYKK KFSLFPVFKY FKKILPETNI YFSQNLTECS
110 120 130 140 150
SIKSGELIIL ENVRFNQGEK ENSKILSKKY ATLCDIFVMD AFGAIHRNEA
160 170 180 190 200
STNGIIKYAK LACSGLLLES ELKTLNSALT NPVRPMVAIV GGAKVSTKFK
210 220 230 240 250
TLTTLAKISD TLIVGGGIAN TFISIDHNIG KSLHDPKFIE QAKILKEKYN
260 270 280 290 300
IFIPTDSRVS TTFTYDSIAT IKSTSDIHAN EEIMDFGDIS IKNMINIIKK
310 320 330 340 350
AKTILWNGPI GVFEFKNFSK GTEQLSKAIA SSDAFSIAGG GDTLSVVEMF
360 370 380 390
KVQNNISYLS TGGGSFLKFL EGNKFRIIEL LEKHFNKFKN NNF
Length:393
Mass (Da):43,647
Last modified:March 28, 2003 - v1
Checksum:i9DCBD57CCDE00530
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016826 Genomic DNA Translation: AAO27112.1
RefSeqiWP_011091513.1, NC_004545.1

Genome annotation databases

EnsemblBacteriaiAAO27112; AAO27112; bbp_400
KEGGibab:bbp_400

Entry informationi

Entry nameiPGK_BUCBP
AccessioniPrimary (citable) accession number: P59461
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 28, 2003
Last sequence update: March 28, 2003
Last modified: May 23, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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