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Reviewed, UniProtKB/Swiss-Prot P59450 (MURB_BUCBP)

Last modified November 3, 2009. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    UDP-N-acetylenolpyruvoylglucosamine reductase
    EC=1.1.1.158
Alternative name(s):
    UDP-N-acetylmuramate dehydrogenase
Gene names
Name: murB
Ordered Locus Names: bbp_046
OrganismBuchnera aphidicola subsp. Baizongia pistaciae [Complete proteome] [HAMAP]
Taxonomic identifier135842 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length334 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Cell wall formation By similarity.

Catalytic activity

UDP-N-acetylmuramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADPH. HAMAP MF_00037

Cofactor

FAD By similarity.

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00037

Subcellular location

Cytoplasm Probable.

Sequence similarities

Belongs to the murB family.

Contains 1 FAD-binding PCMH-type domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 334334UDP-N-acetylenolpyruvoylglucosamine reductase HAMAP MF_00037
PRO_0000179189

Regions

Domain16 – 186171FAD-binding PCMH-type

Sites

Active site1621 By similarity
Active site2321Proton donor By similarity
Active site3291 By similarity

Sequences

Sequence LengthMass (Da)Tools
P59450-1 [UniParc].

Last modified March 28, 2003. Version 1.
Checksum: C0703B4E5BA64B05

FASTA33438,428
        10         20         30         40         50         60 
MKTYYTSLKK FHTFKINVFA KKIIIVKTIK TLIKTWKKCN QENLPFLLLG KGSNVLFTKN 

        70         80         90        100        110        120 
YNGFVVVNRI SGITIHEQKD YWLLHVKGGT KWNNLVKYTI QKKIYGLENL ALIPGTVGAA 

       130        140        150        160        170        180 
PIQNIGAYGV EFKDVCQYVD VLYLNNSKIV RINSNNCLFG YRDSIFKKKH NPNSIILSVG 

       190        200        210        220        230        240 
IKLPKTWKPK ISHLELQKLS FKNITSHQIF HYICKLRKKK LPNPKKIGNA GSFFKNPIIK 

       250        260        270        280        290        300 
KNKAHKIICE YKDLPFYPEP HGMIKLSAGW LIEKCKLKNF SVGNAKIYHK QALILINKNN 

       310        320        330 
LATSKNIIKL AKIIISKVKK KFDITLELEV QIIN 

« Hide

Cross-references

Sequence databases

AE016826 Genomic DNA. Translation: AAO26785.1.
RefSeqNP_777680.1.

3D structure databases

HSSPHSSP built from PDB template 2MBR based on UniProtKB P08373.
ModBaseSearch...

Genome annotation databases

GeneID1058361.
GenomeReviewsGene locus bbp_046 in contig AE016826_GR.
KEGGbab:bbp046.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMP59450.
OMAIGNAGSF.

Enzyme and pathway databases

BioCycBAPH224915:BBP_046-MON.

Family and domain databases

HAMAPMF_00037.
[Tree]
InterProIPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR016167. FAD-bd_2_sub1.
IPR003170. MurB.
IPR011601. MurB_C.
IPR006094. Oxid_FAD_bind_N.
[Graphical view]
Gene3DG3DSA:3.30.465.10. CO_DH_flavoprot_FAD-bd_sub2. 1 hit.
G3DSA:3.30.43.10. FAD-binding_2_sub1. 1 hit.
G3DSA:3.90.78.10. MurB_C. 1 hit.
PANTHERPTHR21071. MurB. 1 hit.
PfamPF01565. FAD_binding_4. 1 hit.
PF02873. MurB_C. 1 hit.
[Graphical view]
TIGRFAMsTIGR00179. murB. 1 hit.
PROSITEPS51387. FAD_PCMH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMURB_BUCBP
AccessionPrimary (citable) accession number: P59450
Entry history
Integrated into UniProtKB/Swiss-Prot: March 28, 2003
Last sequence update: March 28, 2003
Last modified: November 3, 2009
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents