Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P59382

- PXMP4_RAT

UniProt

P59382 - PXMP4_RAT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Peroxisomal membrane protein 4

Gene

Pxmp4

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Peroxisomal membrane protein 4
Alternative name(s):
24 kDa peroxisomal intrinsic membrane protein
Gene namesi
Name:Pxmp4
Synonyms:Pmp24
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 3

Organism-specific databases

RGDi628782. Pxmp4.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. peroxisomal membrane Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 212211Peroxisomal membrane protein 4PRO_0000218934Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi206 – 2061N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiP59382.

PTM databases

PhosphoSiteiP59382.

Expressioni

Tissue specificityi

Liver.

Gene expression databases

GenevestigatoriP59382.

Interactioni

Subunit structurei

Interacts with PEX19.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000022914.

Structurei

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei97 – 11721HelicalSequence AnalysisAdd
BLAST
Transmembranei151 – 17121HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG79127.
GeneTreeiENSGT00390000001562.
HOGENOMiHOG000157771.
HOVERGENiHBG053773.
InParanoidiP59382.
KOiK13350.
OMAiQATYTHS.
OrthoDBiEOG7NSB3Q.
PhylomeDBiP59382.
TreeFamiTF105313.

Family and domain databases

InterProiIPR019531. Pmp4.
IPR003397. Tim17/Tim22/Tim23/PMP24.
[Graphical view]
PfamiPF02466. Tim17. 1 hit.
[Graphical view]
PIRSFiPIRSF013674. PXMP4. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P59382-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAAPPQLRAL LQAVNKLLRQ RRYHAALAVI KGFRNGAVYG VKIRAPHALV
60 70 80 90 100
MTFLFRSGSL QEKLQAILKA TYTHSRNLAC FVFTYKSLQA LQSHVQGGTH
110 120 130 140 150
QMHSFLAAFI GGLLLFGENN NINSQINMYL TSRVLFALCR LGVEKGYIPA
160 170 180 190 200
LKWDPFPLHT AVIWGLVLWL FEYHRPTLQP SLQSSMTYLY EDSNVWHDLS
210
DFLIFNKSRP SK
Length:212
Mass (Da):24,136
Last modified:January 23, 2007 - v2
Checksum:i07D3A5F0A7841A36
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY151834 mRNA. Translation: AAN72218.1.
BC081699 mRNA. Translation: AAH81699.1.
RefSeqiNP_757377.1. NM_172223.2.
UniGeneiRn.7752.

Genome annotation databases

EnsembliENSRNOT00000022914; ENSRNOP00000022914; ENSRNOG00000016975.
GeneIDi282634.
KEGGirno:282634.
UCSCiRGD:628782. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY151834 mRNA. Translation: AAN72218.1 .
BC081699 mRNA. Translation: AAH81699.1 .
RefSeqi NP_757377.1. NM_172223.2.
UniGenei Rn.7752.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10116.ENSRNOP00000022914.

PTM databases

PhosphoSitei P59382.

Proteomic databases

PRIDEi P59382.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000022914 ; ENSRNOP00000022914 ; ENSRNOG00000016975 .
GeneIDi 282634.
KEGGi rno:282634.
UCSCi RGD:628782. rat.

Organism-specific databases

CTDi 11264.
RGDi 628782. Pxmp4.

Phylogenomic databases

eggNOGi NOG79127.
GeneTreei ENSGT00390000001562.
HOGENOMi HOG000157771.
HOVERGENi HBG053773.
InParanoidi P59382.
KOi K13350.
OMAi QATYTHS.
OrthoDBi EOG7NSB3Q.
PhylomeDBi P59382.
TreeFami TF105313.

Miscellaneous databases

NextBioi 624827.
PROi P59382.

Gene expression databases

Genevestigatori P59382.

Family and domain databases

InterProi IPR019531. Pmp4.
IPR003397. Tim17/Tim22/Tim23/PMP24.
[Graphical view ]
Pfami PF02466. Tim17. 1 hit.
[Graphical view ]
PIRSFi PIRSF013674. PXMP4. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A new Rattus norvegicus gene is highly homologous to Mus musculus PMP24 protein."
    Yao R., Wang Y., You M.
    Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: Fischer 344.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Heart.
  3. "Identification of a 24 kDa intrinsic membrane protein from mammalian peroxisomes."
    Reguenga C., Oliveira M.E.M., Gouveia A.M.M., Eckerskorn C., Sa-Miranda C., Azevedo J.E.
    Biochim. Biophys. Acta 1445:337-341(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 2-14, CHARACTERIZATION.
    Tissue: Liver.

Entry informationi

Entry nameiPXMP4_RAT
AccessioniPrimary (citable) accession number: P59382
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 28, 2003
Last sequence update: January 23, 2007
Last modified: October 1, 2014
This is version 74 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3