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P59382 (PXMP4_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Peroxisomal membrane protein 4
Alternative name(s):
24 kDa peroxisomal intrinsic membrane protein
Gene names
Name:Pxmp4
Synonyms:Pmp24
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length212 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Interacts with PEX19 By similarity.

Subcellular location

Peroxisome membrane; Multi-pass membrane protein.

Tissue specificity

Liver.

Sequence similarities

Belongs to the peroxisomal membrane protein PXMP2/4 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Ref.3
Chain2 – 212211Peroxisomal membrane protein 4
PRO_0000218934

Regions

Transmembrane97 – 11721Helical; Potential
Transmembrane151 – 17121Helical; Potential

Amino acid modifications

Glycosylation2061N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
P59382 [UniParc].

Last modified January 23, 2007. Version 2.
Checksum: 07D3A5F0A7841A36

FASTA21224,136
        10         20         30         40         50         60 
MAAPPQLRAL LQAVNKLLRQ RRYHAALAVI KGFRNGAVYG VKIRAPHALV MTFLFRSGSL 

        70         80         90        100        110        120 
QEKLQAILKA TYTHSRNLAC FVFTYKSLQA LQSHVQGGTH QMHSFLAAFI GGLLLFGENN 

       130        140        150        160        170        180 
NINSQINMYL TSRVLFALCR LGVEKGYIPA LKWDPFPLHT AVIWGLVLWL FEYHRPTLQP 

       190        200        210 
SLQSSMTYLY EDSNVWHDLS DFLIFNKSRP SK 

« Hide

References

« Hide 'large scale' references
[1]"A new Rattus norvegicus gene is highly homologous to Mus musculus PMP24 protein."
Yao R., Wang Y., You M.
Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: Fischer 344.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Heart.
[3]"Identification of a 24 kDa intrinsic membrane protein from mammalian peroxisomes."
Reguenga C., Oliveira M.E.M., Gouveia A.M.M., Eckerskorn C., Sa-Miranda C., Azevedo J.E.
Biochim. Biophys. Acta 1445:337-341(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 2-14, CHARACTERIZATION.
Tissue: Liver.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY151834 mRNA. Translation: AAN72218.1.
BC081699 mRNA. Translation: AAH81699.1.
RefSeqNP_757377.1. NM_172223.2.
UniGeneRn.7752.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10116.ENSRNOP00000022914.

PTM databases

PhosphoSiteP59382.

Proteomic databases

PRIDEP59382.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000022914; ENSRNOP00000022914; ENSRNOG00000016975.
GeneID282634.
KEGGrno:282634.
UCSCRGD:628782. rat.

Organism-specific databases

CTD11264.
RGD628782. Pxmp4.

Phylogenomic databases

eggNOGNOG79127.
GeneTreeENSGT00390000001562.
HOGENOMHOG000157771.
HOVERGENHBG053773.
InParanoidP59382.
KOK13350.
OMAYTHSRNL.
OrthoDBEOG7NSB3Q.
PhylomeDBP59382.
TreeFamTF105313.

Gene expression databases

GenevestigatorP59382.

Family and domain databases

InterProIPR019531. Pmp4.
IPR003397. Tim17/Tim22/Tim23/PMP24.
[Graphical view]
PfamPF02466. Tim17. 1 hit.
[Graphical view]
PIRSFPIRSF013674. PXMP4. 1 hit.
ProtoNetSearch...

Other

NextBio624827.
PROP59382.

Entry information

Entry namePXMP4_RAT
AccessionPrimary (citable) accession number: P59382
Entry history
Integrated into UniProtKB/Swiss-Prot: February 28, 2003
Last sequence update: January 23, 2007
Last modified: April 16, 2014
This is version 72 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families