P59363 (YCIB_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable intracellular septation protein A

Gene names

Ordered Locus Names:

BR1935, BS1330_I1929

Organism

Brucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]

Taxonomic identifier

204722 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella suis

Protein attributes

Sequence length	200 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in cell division; probably involved in intracellular septation By similarity. HAMAP-Rule MF_00189
Subcellular location	Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_00189.
Sequence similarities	Belongs to the YciB family.
Sequence caution	The sequence AAN30827.1 differs from that shown. Reason: Erroneous initiation. The sequence AEM19244.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Ontologies

Keywords
Biological process	Cell cycle Cell division Septation
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	barrier septum assembly Inferred from electronic annotation. Source: HAMAP cell cycle Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to plasma membrane Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 200	200	Probable intracellular septation protein A HAMAP-Rule MF_00189		PRO_0000206526
Regions
	Transmembrane	1 – 21	21	Helical; Potential
	Transmembrane	37 – 57	21	Helical; Potential
	Transmembrane	66 – 86	21	Helical; Potential
	Transmembrane	103 – 123	21	Helical; Potential
	Transmembrane	136 – 156	21	Helical; Potential
	Transmembrane	167 – 187	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	P59363 [UniParc]. Last modified November 7, 2003. Version 2. Checksum: F1A1E43A21170DEA	FASTA	200	22,356
	10 20 30 40 50 60 MPPLLKLALE LGPLLVFFFA NARGEMLIER FPILGSIGAP IFLATALFMA ATVIALAISW 70 80 90 100 110 120 SMTRTLPIMP LVSGIVVLVF GALTLWLHND TFIKMKPTIV NTLFGGILLG GLFFGKSLLG 130 140 150 160 170 180 YVFDSAFRLD AEGWRKLTLR WGLFFIFLAI VNEIVWRNFS TDTWVSFKVW GIMPITIVFT 190 200 LLQMPLIQKH SLTDEENTAS

References

[1]

"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts." Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

[2]

"Revised genome sequence of Brucella suis 1330." Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R. J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014291 Genomic DNA. Translation: AAN30827.1. Different initiation. CP002997 Genomic DNA. Translation: AEM19244.1. Different initiation.
RefSeq	NP_698912.1. NC_004310.3. YP_005616736.1. NC_017251.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	204722.BR1935.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAN30827; AAN30827; BR1935. AEM19244; AEM19244; BS1330_I1929.
GeneID	1167635. 12137713.
KEGG	bms:BR1935. bsi:BS1330_I1929.
PATRIC	17792289. VBIBruSui107850_1969.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2917.
HOGENOM	HOG000062587.
KO	K06190.
ProtClustDB	PRK00259.
Family and domain databases
HAMAP	MF_00189. Intracell_septation_prot_A.
InterPro	IPR006008. Intracell_sepatation_prot_A. [Graphical view]
Pfam	PF04279. IspA. 1 hit. [Graphical view]
TIGRFAMs	TIGR00997. ispZ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

YCIB_BRUSU

Accession

Primary (citable) accession number: P59363
Secondary accession number(s): G0K878

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 28, 2003
Last sequence update:	November 7, 2003
Last modified:	May 1, 2013
This is version 63 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program