Reviewed,
UniProtKB/Swiss-Prot P59308 (ARGC2_PSEPK)
Last modified
November 3, 2009.
Version 54.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: N-acetyl-gamma-glutamyl-phosphate reductase 2 Short name=AGPR 2 EC=1.2.1.38 Alternative name(s): N-acetyl-glutamate semialdehyde dehydrogenase 2 Short name=NAGSA dehydrogenase 2 | ||||
| Gene names |
| ||||
| Organism | Pseudomonas putida (strain KT2440) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 160488 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas |
Protein attributes
| Sequence length | 313 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH. HAMAP MF_01110 |
| Pathway | Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4. HAMAP MF_01110 |
| Subcellular location | Cytoplasm Probable. |
| Sequence similarities | Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Arginine biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | NADP |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | arginine biosynthetic process Inferred from electronic annotation. Source: HAMAP oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | N-acetyl-gamma-glutamyl-phosphate reductase activity Inferred from electronic annotation. Source: HAMAP NAD or NADH bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 313 | 313 | N-acetyl-gamma-glutamyl-phosphate reductase 2 HAMAP MF_01110 | PRO_0000112508 | |||||
Sites | |||||||||
| Active site | 117 | 1 | By similarity | ||||||
Sequences
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References
| [1] | "Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT2440." Nelson K.E., Weinel C., Paulsen I.T., Dodson R.J., Hilbert H., Martins dos Santos V.A.P., Fouts D.E., Gill S.R., Pop M., Holmes M., Brinkac L.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Kolonay J.F., Madupu R., Nelson W.C., White O. Fraser C.M.Environ. Microbiol. 4:799-808(2002) [PubMed: 12534463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| AE015451 Genomic DNA. Translation: AAN69233.1. | |
| RefSeq | NP_745769.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | P59308. |
Genome annotation databases | |
| GeneID | 1046203. |
| GenomeReviews | Gene locus PP_3633 in contig AE015451_GR. |
| KEGG | ppu:PP_3633. |
| NMPDR | fig|160488.1.peg.3599. |
| TIGR | PP_3633. |
Phylogenomic databases | |
| HOGENOM | P59308. |
| OMA | EIQQHAG. |
Enzyme and pathway databases | |
| BioCyc | PPUT160488:PP_3633-MON. |
Family and domain databases | |
| HAMAP | MF_01110. [Tree] |
| InterPro | IPR000706. AGPR_act_site. IPR010136. AGPR_subtype. IPR000534. Semialdehyde_DH_NAD-bd. [Graphical view] |
| Pfam | PF01118. Semialdhyde_dh. 1 hit. [Graphical view] |
| ProDom | PD003765. AGPR_act_site. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| TIGRFAMs | TIGR01851. argC_other. 1 hit. |
| PROSITE | PS01224. ARGC. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | ARGC2_PSEPK | ||||||||
| Accession | Primary (citable) accession number: P59308 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


