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P59308 (ARGC2_PSEPK) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
N-acetyl-gamma-glutamyl-phosphate reductase 2

Short name=AGPR 2
EC=1.2.1.38
Alternative name(s):
N-acetyl-glutamate semialdehyde dehydrogenase 2
Short name=NAGSA dehydrogenase 2
Gene names
Name:argC2
Ordered Locus Names:PP_3633
OrganismPseudomonas putida (strain KT2440) [Complete proteome] [HAMAP]
Taxonomic identifier160488 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length313 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH. HAMAP MF_01110

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4. HAMAP MF_01110

Subcellular location

Cytoplasm Probable HAMAP MF_01110.

Sequence similarities

Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Arginine biosynthesis
   Cellular componentCytoplasm
   LigandNADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processarginine biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionN-acetyl-gamma-glutamyl-phosphate reductase activity

Inferred from electronic annotation. Source: EC

NAD binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 313313N-acetyl-gamma-glutamyl-phosphate reductase 2 HAMAP MF_01110
PRO_0000112508

Sites

Active site1171 By similarity

Sequences

Sequence LengthMass (Da)Tools
P59308 [UniParc].

Last modified February 12, 2003. Version 1.
Checksum: CC4602FB3DF1E335

FASTA31333,396
        10         20         30         40         50         60 
MHTPVVFIDG DQGTTGLQIH ARLQGRSDLR LLTLPEAERK DPQRRCEAIN SADIALLCLP 

        70         80         90        100        110        120 
DDAAREAVAA IHNPQVRVID ASSAHRTTPG WVYGLPELDE QQAERIAQST RVSNPGCYPT 

       130        140        150        160        170        180 
GAIALLHPLV KAGLLPADYP LNIHAVSGYS GGGRAAVERH EQPGAAKAPA LQLYGLELAH 

       190        200        210        220        230        240 
KHVPEIQQHA GLSARPMFMP GYGAYRQGIA LSIPLQLRLL PGQVSAEHLQ ACLEQHYQGA 

       250        260        270        280        290        300 
RHVQVMPLHQ CGAAANLDPE ALNGSNDLRL ALYANPEHGQ VLLTAVFDNL GKGASGAAVQ 

       310 
NLDLMLGALQ AHG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE015451 Genomic DNA. Translation: AAN69233.1.
RefSeqNP_745769.1. NC_002947.3.

3D structure databases

ProteinModelPortalP59308.
ModBaseSearch...

Protein-protein interaction databases

STRINGP59308.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1046203.
GenomeReviewsGene locus PP_3633 in contig AE015451_GR.
KEGGppu:PP_3633.
NMPDRfig|160488.1.peg.3599.
PATRIC19945841. VBIPsePut30601_3866.
TIGRPP_3633.

Phylogenomic databases

eggNOGCOG0002.
HOGENOMHBG294213.
OMAEIQQHAG.
PhylomeDBP59308.
ProtClustDBPRK11863.

Enzyme and pathway databases

BioCycPPUT160488:PP_3633-MONOMER.

Family and domain databases

HAMAPMF_01110. ArgC_type2.
[Tree]
InterProIPR023013. AGPR_AS.
IPR010136. AGPR_type-2.
IPR016040. NAD(P)-bd_dom.
IPR000534. Semialdehyde_DH_NAD-bd.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00145.
PfamPF01118. Semialdhyde_dh. 1 hit.
[Graphical view]
SMARTSM00859. Semialdhyde_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR01851. ArgC_other. 1 hit.
PROSITEPS01224. ARGC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameARGC2_PSEPK
AccessionPrimary (citable) accession number: P59308
Entry history
Integrated into UniProtKB/Swiss-Prot: February 12, 2003
Last sequence update: February 12, 2003
Last modified: January 25, 2012
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families