P59285 (ALLA_PSEPK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ureidoglycolate hydrolase
EC=3.5.3.19

Gene names

Name:	allA
Ordered Locus Names:	PP_4288

Organism

Pseudomonas putida (strain KT2440) [Complete proteome] [HAMAP]

Taxonomic identifier

160488 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › Pseudomonas putida group › Pseudomonas putida

Protein attributes

Sequence length	167 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	(S)-ureidoglycolate + H2O = glyoxylate + 2 NH3 + CO2. HAMAP-Rule MF_00616
Pathway	Nitrogen metabolism; (S)-allantoin degradation; glyoxylate from (S)-ureidoglycolate: step 1/1. HAMAP-Rule MF_00616
Subunit structure	Homodimer. Ref.2
Sequence similarities	Belongs to the ureidoglycolate hydrolase family.

Ontologies

Keywords
Biological process	Purine metabolism
Molecular function	Hydrolase
Technical term	3D-structure Complete proteome
Gene Ontology (GO)
Biological_process	allantoin catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway purine nucleobase catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	ureidoglycolate hydrolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 167

167

Ureidoglycolate hydrolase HAMAP-Rule MF_00616

PRO_0000120551

Secondary structure

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167

Helix Strand Turn

Details...

Beta strand

6 – 8

3

Helix

11 – 14

4

Turn

15 – 17

3

Beta strand

18 – 21

4

Beta strand

29 – 31

3

Turn

32 – 35

4

Beta strand

36 – 45

10

Beta strand

47 – 49

3

Beta strand

53 – 62

10

Beta strand

66 – 70

5

Beta strand

72 – 75

4

Beta strand

81 – 87

7

Beta strand

91 – 96

6

Beta strand

98 – 101

4

Helix

104 – 106

3

Beta strand

108 – 112

5

Beta strand

117 – 120

4

Beta strand

130 – 144

15

Beta strand

151 – 154

4

Helix

157 – 159

3

Beta strand

161 – 163

3

Sequences

	Sequence		Length	Mass (Da)
	P59285 [UniParc]. Last modified February 12, 2003. Version 1. Checksum: 670B9A0AF8A8B1D3	FASTA	167	18,768
	10 20 30 40 50 60 MRTLMIEPLT KEAFAQFGDV IETDGSDHFM INNGSTMRFH KLATVETAEP EDKAIISIFR 70 80 90 100 110 120 ADAQDMPLTV RMLERHPLGS QAFIPLLGNP FLIVVAPVGD APVSGLVRAF RSNGRQGVNY 130 140 150 160 HRGVWHHPVL TIEKRDDFLV VDRSGSGNNC DEHYFTEEQM LILNPHQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT2440." Nelson K.E., Weinel C., Paulsen I.T., Dodson R.J., Hilbert H., Martins dos Santos V.A.P., Fouts D.E., Gill S.R., Pop M., Holmes M., Brinkac L.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Kolonay J.F., Madupu R., Nelson W.C., White O. , Peterson J.D., Khouri H.M., Hance I., Chris Lee P., Holtzapple E.K., Scanlan D., Tran K., Moazzez A., Utterback T.R., Rizzo M., Lee K., Kosack D., Moestl D., Wedler H., Lauber J., Stjepandic D., Hoheisel J., Straetz M., Heim S., Kiewitz C., Eisen J.A., Timmis K.N., Duesterhoeft A., Tuemmler B., Fraser C.M. Environ. Microbiol. 4:799-808(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KT2440.
[2]	"Crystal structure of the putative ureidoglycolate hydrolase pp4288 from Pseudomonas putida, Northeast structural genomics target Ppr49." Northeast structural genomics consortium (NESG) Submitted (NOV-2005) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS), SUBUNIT.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE015451 Genomic DNA. Translation: AAN69868.1.

RefSeq

NP_746404.1. NC_002947.3.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2BDR	X-ray	1.60	A/B	1-167	[»]

ProteinModelPortal

P59285.

SMR

P59285. Positions 1-166.

ModBase

Search...

Protein-protein interaction databases

STRING

160488.PP_4288.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

AAN69868; AAN69868; PP_4288.

GeneID

1041802.

KEGG

ppu:PP_4288.

PATRIC

19947234. VBIPsePut30601_4560.

Organism-specific databases

CMR

Search...

Phylogenomic databases

eggNOG

COG3194.

HOGENOM

HOG000256169.

KO

K01483.

OMA

SQAFIPM.

ProtClustDB

PRK03606.

Enzyme and pathway databases

BioCyc

PPUT160488:GIXO-4289-MONOMER.

UniPathway

UPA00395; UER00656.

Family and domain databases

Gene3D

2.60.120.480. 1 hit.

HAMAP

MF_00616. Ureidogly_hydro.

InterPro

IPR011051. RmlC_Cupin.
IPR007247. Ureidogly_hydro.
IPR023525. Ureidogly_hydro_bac.
IPR024060. Ureidoglycolate_hydrolase_dom.
[Graphical view]

PANTHER

PTHR21221. PTHR21221. 1 hit.

Pfam

PF04115. Ureidogly_hydro. 1 hit.
[Graphical view]

PIRSF

PIRSF017306. Ureidogly_hydro. 1 hit.

SUPFAM

SSF51182. RmlC_like_cupin. 1 hit.

ProtoNet

Search...

Other

EvolutionaryTrace

P59285.

Entry information

Entry name

ALLA_PSEPK

Accession

Primary (citable) accession number: P59285

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 12, 2003
Last sequence update:	February 12, 2003
Last modified:	May 1, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program