Reviewed,
UniProtKB/Swiss-Prot P59220 (CALM7_ARATH)
Last modified
November 4, 2008.
Version 62.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Calmodulin-7 Short name=CaM-7 | ||||||
| Gene names |
| ||||||
| Organism | Arabidopsis thaliana (Mouse-ear cress) [Complete proteome] | ||||||
| Taxonomic identifier | 3702 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis |
Protein attributes
| Sequence length | 149 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Calmodulin mediates the control of a large number of enzymes and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. |
| Miscellaneous | This protein has four functional calcium-binding sites. |
| Sequence similarities | Belongs to the calmodulin family. Contains 4 EF-hand domains. |
Ontologies
Keywords | |
|---|---|
| Domain | Repeat |
| Ligand | Calcium |
| PTM | Acetylation Methylation |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Molecular function | protein binding Inferred from physical interaction. Source: IntAct |
| Complete GO annotation... | |
Binary interactions
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Initiator methionine | 1 | 1 | Removed By similarity | ||||||
| Chain | 2 – 149 | 148 | Calmodulin-7 | PRO_0000198283 | |||||
Regions | |||||||||
| Domain | 8 – 43 | 36 | EF-hand 1 | ||||||
| Domain | 44 – 79 | 36 | EF-hand 2 | ||||||
| Domain | 81 – 116 | 36 | EF-hand 3 | ||||||
| Domain | 117 – 149 | 33 | EF-hand 4 | ||||||
| Calcium binding | 21 – 32 | 12 | 1 By similarity | ||||||
| Calcium binding | 57 – 68 | 12 | 2 By similarity | ||||||
| Calcium binding | 94 – 105 | 12 | 3 By similarity | ||||||
| Calcium binding | 130 – 141 | 12 | 4 By similarity | ||||||
Amino acid modifications | |||||||||
| Modified residue | 2 | 1 | N-acetylalanine By similarity | ||||||
| Modified residue | 116 | 1 | N6,N6,N6-trimethyllysine By similarity | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Characterization of three new members of the Arabidopsis thaliana calmodulin gene family: conserved and highly diverged members of the gene family functionally complement a yeast calmodulin null." Zielinski R.E. Planta 214:446-455(2002) [PubMed: 11855649] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], CHARACTERIZATION. Strain: cv. Columbia. |
| [2] | "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana." Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F.  Tabata S.Nature 408:820-822(2000) [PubMed: 11130713] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia. |
| [3] | "Full-length cDNA from Arabidopsis thaliana." Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. |
| [4] | "Calmodulins and related potential calcium sensors of Arabidopsis." McCormack E., Braam J. New Phytol. 159:585-598(2003) Cited for: GENE FAMILY, NOMENCLATURE. |
Cross-references
Sequence databases | |
|---|---|
| AF178073 mRNA. Translation: AAD53313.1. AL162691 Genomic DNA. Translation: CAB83153.1. AY088477 mRNA. Translation: AAM66013.1. | |
| PIR | T47417. |
| RefSeq | NP_189967.1. |
| UniGene | At.23208 |
3D structure databases | |
| HSSP | HSSP built from PDB template 1F70 based on UniProtKB P02593. |
| SMR | P59220. Positions 1-148. |
| ModBase | Search... |
Protein-protein interaction databases | |
| IntAct | P59220. |
Genome annotation databases | |
| GeneID | 823492. |
| GenomeReviews | Gene locus AT3G43810 in contig BA000014_GR. |
| KEGG | ath:AT3G43810. |
Organism-specific databases | |
| TAIR | At3g43810. |
Gene expression databases | |
| ArrayExpress | P59220. |
| GermOnline | AT3G43810. Arabidopsis thaliana. |
Family and domain databases | |
| InterPro | IPR011992. EF-Hand_type. IPR002048. EF_hand_Ca_bd. [Graphical view] |
| Gene3D | G3DSA:1.10.238.10. EF-Hand_type. 1 hit. |
| Pfam | PF00036. efhand. 4 hits. [Graphical view] |
| ProDom | PD000012. EF-hand. 2 hits. [Graphical view] [Entries sharing at least one domain] |
| SMART | SM00054. EFh. 4 hits. [Graphical view] |
| PROSITE | PS00018. EF_HAND_1. 4 hits. PS50222. EF_HAND_2. 4 hits. [Graphical view] |
| BLOCKS | Search... |
| ProtoNet | Search... |
Entry information
| Entry name | CALM7_ARATH | ||||||||
| Accession | Primary (citable) accession number: P59220 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||
Relevant documents
| Arabidopsis thaliana Arabidopsis thaliana: entries and gene names |
| SIMILARITY comments Index of protein domains and families |
