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Protein

Uncharacterized Nudix hydrolase YfcD

Gene

yfcD

Organism
Shigella flexneri
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Mg2+By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi88MagnesiumBy similarity1
Metal bindingi92MagnesiumBy similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Magnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized Nudix hydrolase YfcD (EC:3.6.-.-)
Gene namesi
Name:yfcD
Ordered Locus Names:SF2375, S2510
OrganismiShigella flexneri
Taxonomic identifieri623 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000002673 Componenti: Chromosome
  • UP000001006 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000570821 – 180Uncharacterized Nudix hydrolase YfcDAdd BLAST180

Proteomic databases

PaxDbiP59196.

Interactioni

Protein-protein interaction databases

STRINGi198214.SF2375.

Structurei

3D structure databases

ProteinModelPortaliP59196.
SMRiP59196.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 163Nudix hydrolasePROSITE-ProRule annotationAdd BLAST129

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi72 – 94Nudix boxAdd BLAST23

Sequence similaritiesi

Belongs to the Nudix hydrolase family.Curated
Contains 1 nudix hydrolase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105PTV. Bacteria.
ENOG410ZCV3. LUCA.
HOGENOMiHOG000274108.
OMAiGYWDVAA.

Family and domain databases

Gene3Di3.90.79.10. 1 hit.
InterProiIPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
IPR024195. NUDIX_hydrolase_YfcD_pred.
[Graphical view]
PfamiPF00293. NUDIX. 1 hit.
[Graphical view]
PIRSFiPIRSF017340. Nudix_hydro. 1 hit.
SUPFAMiSSF55811. SSF55811. 1 hit.
PROSITEiPS51462. NUDIX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P59196-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQRRLASTE WVDIVNEENE VIAQASREQM RAQCLRHRAT YIVVHDGMGK
60 70 80 90 100
ILVQRRTETK DFLPGMLDAT AGGVVQADEQ LLESARREAE EELGIAGVPF
110 120 130 140 150
AEHGQFYFED KNCRVWGALF SCVSHGPFAL QEDEVSGVCW LTPEEITARC
160 170 180
DEFTPDSLKA LALWMKRNAK NEAVETETAE
Length:180
Mass (Da):20,304
Last modified:January 10, 2003 - v1
Checksum:i83FC88B5BC73FF8B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005674 Genomic DNA. Translation: AAN43888.1.
AE014073 Genomic DNA. Translation: AAP17706.1.
RefSeqiNP_708181.1. NC_004337.2.
WP_000437938.1. NZ_LVJC01000007.1.

Genome annotation databases

EnsemblBacteriaiAAN43888; AAN43888; SF2375.
AAP17706; AAP17706; S2510.
GeneIDi1026560.
KEGGisfl:SF2375.
sft:NCTC1_02610.
sfx:S2510.
PATRICi18706615. VBIShiFle31049_2783.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005674 Genomic DNA. Translation: AAN43888.1.
AE014073 Genomic DNA. Translation: AAP17706.1.
RefSeqiNP_708181.1. NC_004337.2.
WP_000437938.1. NZ_LVJC01000007.1.

3D structure databases

ProteinModelPortaliP59196.
SMRiP59196.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi198214.SF2375.

Proteomic databases

PaxDbiP59196.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN43888; AAN43888; SF2375.
AAP17706; AAP17706; S2510.
GeneIDi1026560.
KEGGisfl:SF2375.
sft:NCTC1_02610.
sfx:S2510.
PATRICi18706615. VBIShiFle31049_2783.

Phylogenomic databases

eggNOGiENOG4105PTV. Bacteria.
ENOG410ZCV3. LUCA.
HOGENOMiHOG000274108.
OMAiGYWDVAA.

Family and domain databases

Gene3Di3.90.79.10. 1 hit.
InterProiIPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
IPR024195. NUDIX_hydrolase_YfcD_pred.
[Graphical view]
PfamiPF00293. NUDIX. 1 hit.
[Graphical view]
PIRSFiPIRSF017340. Nudix_hydro. 1 hit.
SUPFAMiSSF55811. SSF55811. 1 hit.
PROSITEiPS51462. NUDIX. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYFCD_SHIFL
AccessioniPrimary (citable) accession number: P59196
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 10, 2003
Last sequence update: January 10, 2003
Last modified: November 2, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.