ID   TSAS2_HUMAN             Reviewed;          65 AA.
AC   P59090; Q3MIX8;
DT   15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   15-NOV-2002, sequence version 1.
DT   13-SEP-2023, entry version 89.
DE   RecName: Full=Putative uncharacterized protein TSPEAR-AS2 {ECO:0000312|HGNC:HGNC:16428};
DE   AltName: Full=TSPEAR antisense RNA 2 {ECO:0000312|HGNC:HGNC:16428};
DE   AltName: Full=TSPEAR antisense gene protein 2 {ECO:0000305};
GN   Name=TSPEAR-AS2 {ECO:0000312|HGNC:HGNC:16428};
GN   Synonyms=C21orf90 {ECO:0000312|HGNC:HGNC:16428};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), AND TISSUE SPECIFICITY.
RX   PubMed=12036297; DOI=10.1006/geno.2002.6781;
RA   Reymond A., Camargo A.A., Deutsch S., Stevenson B.J., Parmigiani R.B.,
RA   Ucla C., Bettoni F., Rossier C., Lyle R., Guipponi M., de Souza S.,
RA   Iseli C., Jongeneel C.V., Bucher P., Simpson A.J.G., Antonarakis S.E.;
RT   "Nineteen additional unpredicted transcripts from human chromosome 21.";
RL   Genomics 79:824-832(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10830953; DOI=10.1038/35012518;
RA   Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T., Park H.-S.,
RA   Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y., Soeda E., Ohki M.,
RA   Takagi T., Sakaki Y., Taudien S., Blechschmidt K., Polley A., Menzel U.,
RA   Delabar J., Kumpf K., Lehmann R., Patterson D., Reichwald K., Rump A.,
RA   Schillhabel M., Schudy A., Zimmermann W., Rosenthal A., Kudoh J.,
RA   Shibuya K., Kawasaki K., Asakawa S., Shintani A., Sasaki T., Nagamine K.,
RA   Mitsuyama S., Antonarakis S.E., Minoshima S., Shimizu N., Nordsiek G.,
RA   Hornischer K., Brandt P., Scharfe M., Schoen O., Desario A., Reichelt J.,
RA   Kauer G., Bloecker H., Ramser J., Beck A., Klages S., Hennig S.,
RA   Riesselmann L., Dagand E., Wehrmeyer S., Borzym K., Gardiner K.,
RA   Nizetic D., Francis F., Lehrach H., Reinhardt R., Yaspo M.-L.;
RT   "The DNA sequence of human chromosome 21.";
RL   Nature 405:311-319(2000).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC   TISSUE=Cerebellum;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=P59090-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=P59090-2; Sequence=VSP_003838, VSP_003839;
CC   -!- TISSUE SPECIFICITY: Widely expressed. Not expressed in liver and
CC       muscle. {ECO:0000269|PubMed:12036297}.
CC   -!- CAUTION: Product of a dubious gene prediction. Encoded in intron of
CC       TSPEAR. {ECO:0000305}.
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DR   EMBL; AF426269; AAM53525.1; -; mRNA.
DR   EMBL; AF426270; AAM53526.1; -; mRNA.
DR   EMBL; AP001066; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC101650; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; BC101654; -; NOT_ANNOTATED_CDS; mRNA.
DR   AlphaFoldDB; P59090; -.
DR   BioMuta; HGNC:16428; -.
DR   ProteomicsDB; 57128; -. [P59090-1]
DR   ProteomicsDB; 57129; -. [P59090-2]
DR   AGR; HGNC:16428; -.
DR   GeneCards; TSPEAR-AS2; -.
DR   HGNC; HGNC:16428; TSPEAR-AS2.
DR   neXtProt; NX_P59090; -.
DR   InParanoid; P59090; -.
DR   PhylomeDB; P59090; -.
DR   PathwayCommons; P59090; -.
DR   Pharos; P59090; Tdark.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; P59090; Protein.
PE   5: Uncertain;
KW   Alternative splicing; Reference proteome.
FT   CHAIN           1..65
FT                   /note="Putative uncharacterized protein TSPEAR-AS2"
FT                   /id="PRO_0000079540"
FT   REGION          45..65
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         15..37
FT                   /note="FSGFLSNIRGPLAGEDGMGDTQL -> GARLCSQDPLEARPLPPTSSFVR
FT                   (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:12036297"
FT                   /id="VSP_003838"
FT   VAR_SEQ         38..65
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:12036297"
FT                   /id="VSP_003839"
SQ   SEQUENCE   65 AA;  7097 MW;  2B103050E43F93A0 CRC64;
     MGNPRLPRLL CALKFSGFLS NIRGPLAGED GMGDTQLARV RDSALKTPWR PAPCPPPAHS
     LDDWK
//