Reviewed,
UniProtKB/Swiss-Prot P59090 (CU090_HUMAN)
Last modified
December 15, 2009.
Version 39.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Alternative products · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Uncharacterized protein C21orf90 | ||
| Gene names |
| ||
| Organism | Homo sapiens (Human) [Complete proteome] | ||
| Taxonomic identifier | 9606 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Protein attributes
| Sequence length | 65 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Tissue specificity | Widely expressed. Not expressed in liver and muscle. Ref.1 |
Ontologies
| Keywords | |
|---|---|
| Coding sequence diversity | Alternative splicing |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| None. [Check GOA] | |
Alternative products
| This entry describes 2 isoforms produced by alternative splicing. [Align] [Select] | ||||||
| Isoform 1 (identifier: P59090-1) This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. | ||||||
| Isoform 2 (identifier: P59090-2) The sequence of this isoform differs from the canonical sequence as follows: 15-37: FSGFLSNIRGPLAGEDGMGDTQL → GARLCSQDPLEARPLPPTSSFVR 38-65: Missing. |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 65 | 65 | Uncharacterized protein C21orf90 | PRO_0000079540 | |||||
Natural variations | |||||||||
| Alternative sequence | 15 – 37 | 23 | FSGFL…GDTQL → GARLCSQDPLEARPLPPTSS FVR in isoform 2. | VSP_003838 | |||||
| Alternative sequence | 38 – 65 | 28 | Missing in isoform 2. | VSP_003839 | |||||
Sequences
References
| « Hide 'large scale' references | |
| [1] | "Nineteen additional unpredicted transcripts from human chromosome 21." Reymond A., Camargo A.A., Deutsch S., Stevenson B.J., Parmigiani R.B., Ucla C., Bettoni F., Rossier C., Lyle R., Guipponi M., de Souza S., Iseli C., Jongeneel C.V., Bucher P., Simpson A.J.G., Antonarakis S.E. Genomics 79:824-832(2002) [PubMed: 12036297] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), TISSUE SPECIFICITY. |
| [2] | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Cerebellum. |
Cross-references
Sequence databases | |
|---|---|
| AF426269 mRNA. Translation: AAM53525.1. AF426270 mRNA. Translation: AAM53526.1. BC101650 mRNA. Translation: AAI01651.1. BC101654 mRNA. Translation: AAI01655.1. | |
| IPI | IPI00171428. IPI00219882. |
| UniGene | Hs.592163 |
3D structure databases | |
| ModBase | Search... |
Proteomic databases | |
| PRIDE | P59090. |
Genome annotation databases | |
| Ensembl | ENST00000330490; ENSP00000333592; ENSG00000182912; Homo sapiens. [Genome view] |
Organism-specific databases | |
| GeneCards | GC21P044761. |
| HGNC | HGNC:16428. C21orf90. |
| PharmGKB | PA25878. |
| GenAtlas | Search... |
Phylogenomic databases | |
| InParanoid | P59090. |
| OMA | EDGMGDT. |
Gene expression databases | |
| ArrayExpress | P59090. |
| Bgee | P59090. |
| CleanEx | HS_C21orf90. |
| Genevestigator | P59090. |
| GermOnline | ENSG00000182912. Homo sapiens. |
Family and domain databases | |
| ProtoNet | Search... |
Entry information
| Entry name | CU090_HUMAN | ||||||||
| Accession | Primary (citable) accession number: P59090 Secondary accession number(s): Q3MIX8 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HPI (Human Proteome Initiative) | ||||||||
| Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. | ||||||||
Relevant documents
| Human chromosome 21 Human chromosome 21: entries, gene names and cross-references to MIM |

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