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P59082 (LFS_ALLCE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Lachrymatory-factor synthase
Gene names
Name:LFS
OrganismAllium cepa (Onion)
Taxonomic identifier4679 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaAsparagalesAmaryllidaceaeAllioideaeAllieaeAllium

Protein attributes

Sequence length169 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Produces lacrymatory factor (propanthial S-oxide) from 1-propenylsulphenic acid, an unstable compound resulting from the degradation of trans-1-propenyl-L-cysteine sulphoxide (PRENCSO) by alliinase.

Subcellular location

Vacuole Probable.

Biotechnological use

It may be possible to develop a non-lachrymal onion that still retains its characteristic flavor and high nutritional value by down-regulating the activity of this enzyme.

Ontologies

Keywords
   Cellular componentVacuole
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Cellular_componentvacuole

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Propeptide1 – 1212
PRO_0000021591
Chain13 – 169157Lachrymatory-factor synthase
PRO_0000021592

Sequences

Sequence LengthMass (Da)Tools
P59082 [UniParc].

Last modified November 8, 2002. Version 1.
Checksum: D1D2DBD00A244EF1

FASTA16919,057
        10         20         30         40         50         60 
MELNPGAPAV VADSANGARK WSGKVHALLP NTKPEQAWTL LKDFINLHKV MPSLSVCELV 

        70         80         90        100        110        120 
EGEANVVGCV RYVKGIMHPI EEEFWAKEKL VALDNKNMSY SYIFTECFTG YEDYTATMQI 

       130        140        150        160 
VEGPEHKGSR FDWSFQCKYI EGMTESAFTE ILQHWATEIG QKIEEVCSA 

« Hide

References

[1]"An onion enzyme that makes the eyes water."
Imai S., Tsuge N., Tomotake M., Nagatome Y., Sawada H., Nagata T., Kumagai H.
Nature 419:685-685(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 13-22.

Web resources

Protein Spotlight

No LFS, no cry - Issue 28 of November 2002

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB089203 mRNA. Translation: BAC21275.1.

3D structure databases

ProteinModelPortalP59082.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-13498.

Family and domain databases

Gene3D3.30.530.20. 1 hit.
InterProIPR019587. Polyketide_cyclase/dehydratase.
IPR023393. START-like_dom.
[Graphical view]
PfamPF10604. Polyketide_cyc2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLFS_ALLCE
AccessionPrimary (citable) accession number: P59082
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: November 8, 2002
Last modified: February 19, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Protein Spotlight

Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries