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Protein

p53 and DNA damage-regulated protein 1

Gene

Pdrg1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May play a role in chaperone-mediated protein folding.Curated

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Names & Taxonomyi

Protein namesi
Recommended name:
p53 and DNA damage-regulated protein 1
Gene namesi
Name:Pdrg1
Synonyms:Pdrg
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1915809. Pdrg1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 133133p53 and DNA damage-regulated protein 1PRO_0000058278Add
BLAST

Proteomic databases

EPDiP59048.
PaxDbiP59048.
PeptideAtlasiP59048.
PRIDEiP59048.

PTM databases

iPTMnetiP59048.
PhosphoSiteiP59048.

Expressioni

Gene expression databases

BgeeiENSMUSG00000027472.
CleanExiMM_PDRG1.
ExpressionAtlasiP59048. baseline and differential.
GenevisibleiP59048. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000028972.

Family & Domainsi

Sequence similaritiesi

Belongs to the prefoldin subunit beta family.Curated

Phylogenomic databases

eggNOGiENOG410IYXP. Eukaryota.
ENOG41127ER. LUCA.
HOGENOMiHOG000007729.
HOVERGENiHBG053553.
InParanoidiP59048.
OMAiGNMFIRM.
OrthoDBiEOG091G0USB.
PhylomeDBiP59048.
TreeFamiTF329240.

Family and domain databases

InterProiIPR030482. PDRG1.
IPR002777. PFD_beta-like.
IPR009053. Prefoldin.
[Graphical view]
PANTHERiPTHR21162:SF0. PTHR21162:SF0. 1 hit.
PfamiPF01920. Prefoldin_2. 1 hit.
[Graphical view]
SUPFAMiSSF46579. SSF46579. 1 hit.

Sequencei

Sequence statusi: Complete.

P59048-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSPEAERVL RYLVEVEELA EAVLSDKRQI VDLDTKRNQN REGLRALQKD
60 70 80 90 100
LSVSEDVMVC FGNMFIKMPH PKTKEMIQKD QEHLDKEIER LRSQLKVKVN
110 120 130
RLFEAQGKPE LKGFNLNPLS PDEVKALKVI LKG
Length:133
Mass (Da):15,382
Last modified:October 19, 2002 - v1
Checksum:i9CC5E82C14556E72
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY286302 mRNA. Translation: AAP45330.1.
BC031699 mRNA. Translation: AAH31699.1.
CCDSiCCDS16904.1.
RefSeqiNP_849270.1. NM_178939.2.
UniGeneiMm.12746.

Genome annotation databases

EnsembliENSMUST00000028972; ENSMUSP00000028972; ENSMUSG00000027472.
GeneIDi68559.
KEGGimmu:68559.
UCSCiuc008ngz.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY286302 mRNA. Translation: AAP45330.1.
BC031699 mRNA. Translation: AAH31699.1.
CCDSiCCDS16904.1.
RefSeqiNP_849270.1. NM_178939.2.
UniGeneiMm.12746.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000028972.

PTM databases

iPTMnetiP59048.
PhosphoSiteiP59048.

Proteomic databases

EPDiP59048.
PaxDbiP59048.
PeptideAtlasiP59048.
PRIDEiP59048.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000028972; ENSMUSP00000028972; ENSMUSG00000027472.
GeneIDi68559.
KEGGimmu:68559.
UCSCiuc008ngz.1. mouse.

Organism-specific databases

CTDi81572.
MGIiMGI:1915809. Pdrg1.

Phylogenomic databases

eggNOGiENOG410IYXP. Eukaryota.
ENOG41127ER. LUCA.
HOGENOMiHOG000007729.
HOVERGENiHBG053553.
InParanoidiP59048.
OMAiGNMFIRM.
OrthoDBiEOG091G0USB.
PhylomeDBiP59048.
TreeFamiTF329240.

Miscellaneous databases

ChiTaRSiPdrg1. mouse.
PROiP59048.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000027472.
CleanExiMM_PDRG1.
ExpressionAtlasiP59048. baseline and differential.
GenevisibleiP59048. MM.

Family and domain databases

InterProiIPR030482. PDRG1.
IPR002777. PFD_beta-like.
IPR009053. Prefoldin.
[Graphical view]
PANTHERiPTHR21162:SF0. PTHR21162:SF0. 1 hit.
PfamiPF01920. Prefoldin_2. 1 hit.
[Graphical view]
SUPFAMiSSF46579. SSF46579. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPDRG1_MOUSE
AccessioniPrimary (citable) accession number: P59048
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 19, 2002
Last sequence update: October 19, 2002
Last modified: September 7, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.