Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P58989

- CRA1_HOMGA

UniProt

P58989 - CRA1_HOMGA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Crustacyanin-A1 subunit

Gene
N/A
Organism
Homarus gammarus (European lobster) (Homarus vulgaris)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Binds the carotenoid astaxanthin (AXT) which provides the blue coloration to the carapace of the lobster.

GO - Molecular functioni

  1. pigment binding Source: UniProtKB-KW
  2. small molecule binding Source: InterPro

GO - Biological processi

  1. protein-chromophore linkage Source: UniProtKB-KW
  2. transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

Chromophore, Pigment

Names & Taxonomyi

Protein namesi
Recommended name:
Crustacyanin-A1 subunit
OrganismiHomarus gammarus (European lobster) (Homarus vulgaris)
Taxonomic identifieri6707 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMalacostracaEumalacostracaEucaridaDecapodaPleocyemataAstacideaNephropoideaNephropidaeHomarus

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 181181Crustacyanin-A1 subunitPRO_0000201009Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi12 ↔ 121
Disulfide bondi51 ↔ 173
Disulfide bondi117 ↔ 150

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Found in the carapace.

Interactioni

Subunit structurei

Oligomer; Can form dimers (beta-crustacyanin); or complexes of 16 subunits (alpha-crustacyanin). There are five types of subunits: A1, A2, A3, C1 and C2.1 Publication

Protein-protein interaction databases

MINTiMINT-242140.

Structurei

Secondary structure

1
181
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi7 – 115Combined sources
Helixi17 – 248Combined sources
Helixi25 – 273Combined sources
Helixi28 – 314Combined sources
Beta strandi33 – 419Combined sources
Beta strandi48 – 5811Combined sources
Beta strandi63 – 719Combined sources
Beta strandi74 – 8512Combined sources
Beta strandi91 – 977Combined sources
Beta strandi98 – 1003Combined sources
Beta strandi102 – 1109Combined sources
Beta strandi112 – 12312Combined sources
Beta strandi127 – 14115Combined sources
Helixi144 – 15613Combined sources
Helixi161 – 1633Combined sources
Beta strandi164 – 1663Combined sources
Beta strandi170 – 1734Combined sources
Helixi175 – 1784Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1GKAX-ray3.23A2-181[»]
1S44X-ray1.60A/B2-181[»]
ProteinModelPortaliP58989.
SMRiP58989. Positions 2-181.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP58989.

Family & Domainsi

Sequence similaritiesi

Belongs to the calycin superfamily. Lipocalin family.Curated

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR003057. Invtbrt_color.
IPR002345. Lipocalin.
IPR022271. Lipocalin_ApoD.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
[Graphical view]
PfamiPF00061. Lipocalin. 1 hit.
[Graphical view]
PIRSFiPIRSF036893. Lipocalin_ApoD. 1 hit.
PRINTSiPR01273. INVTBRTCOLOR.
PR00179. LIPOCALIN.
SUPFAMiSSF50814. SSF50814. 1 hit.

Sequencei

Sequence statusi: Complete.

P58989-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
DKIPNFVVPG KCASVDRNKL WAEQTPNRNS YAGVWYQFAL TNNPYQLIEK
60 70 80 90 100
CVRNEYSFDG KQFVIKSTGI AYDGNLLKRN GKLYPNPFGE PHLSIDYENS
110 120 130 140 150
FAAPLVILET DYSNYACLYS CIDYNFGYHS DFSFIFSRSA NLADQYVKKC
160 170 180
EAAFKNINVD TTRFVKTVQG SSCPYDTQKT V
Length:181
Mass (Da):20,652
Last modified:August 13, 2002 - v1
Checksum:i285EADC1A4F2E353
GO

Cross-referencesi

Web resourcesi

Protein Spotlight

Squeeze me - Issue 26 of September 2002

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1GKA X-ray 3.23 A 2-181 [» ]
1S44 X-ray 1.60 A/B 2-181 [» ]
ProteinModelPortali P58989.
SMRi P58989. Positions 2-181.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

MINTi MINT-242140.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei P58989.

Family and domain databases

Gene3Di 2.40.128.20. 1 hit.
InterProi IPR012674. Calycin.
IPR011038. Calycin-like.
IPR003057. Invtbrt_color.
IPR002345. Lipocalin.
IPR022271. Lipocalin_ApoD.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
[Graphical view ]
Pfami PF00061. Lipocalin. 1 hit.
[Graphical view ]
PIRSFi PIRSF036893. Lipocalin_ApoD. 1 hit.
PRINTSi PR01273. INVTBRTCOLOR.
PR00179. LIPOCALIN.
SUPFAMi SSF50814. SSF50814. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: X-RAY CRYSTALLOGRAPHY (1.15 ANGSTROMS) OF HOMODIMER.
  2. "The molecular basis of the coloration mechanism in lobster shell: beta-crustacyanin at 3.2-A resolution."
    Cianci M., Rizkallah P.J., Olczak A., Raftery J., Chayen N.E., Zagalsky P.F., Helliwell J.R.
    Proc. Natl. Acad. Sci. U.S.A. 99:9795-9800(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS) OF HETERODIMER OF A1 AND A3 IN COMPLEX WITH ASTAXANTHIN.

Entry informationi

Entry nameiCRA1_HOMGA
AccessioniPrimary (citable) accession number: P58989
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 13, 2002
Last sequence update: August 13, 2002
Last modified: October 29, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Protein Spotlight
    Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3