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Protein

Crustacyanin-A1 subunit

Gene
N/A
Organism
Homarus gammarus (European lobster) (Homarus vulgaris)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Binds the carotenoid astaxanthin (AXT) which provides the blue coloration to the carapace of the lobster.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

Chromophore, Pigment

Names & Taxonomyi

Protein namesi
Recommended name:
Crustacyanin-A1 subunit
OrganismiHomarus gammarus (European lobster) (Homarus vulgaris)
Taxonomic identifieri6707 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMalacostracaEumalacostracaEucaridaDecapodaPleocyemataAstacideaNephropoideaNephropidaeHomarus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002010091 – 181Crustacyanin-A1 subunitAdd BLAST181

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi12 ↔ 121
Disulfide bondi51 ↔ 173
Disulfide bondi117 ↔ 150

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Found in the carapace.

Interactioni

Subunit structurei

Oligomer; Can form dimers (beta-crustacyanin); or complexes of 16 subunits (alpha-crustacyanin). There are five types of subunits: A1, A2, A3, C1 and C2.1 Publication

Protein-protein interaction databases

MINTiMINT-242140.

Structurei

Secondary structure

1181
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi7 – 11Combined sources5
Helixi17 – 24Combined sources8
Helixi25 – 27Combined sources3
Helixi28 – 31Combined sources4
Beta strandi33 – 41Combined sources9
Beta strandi48 – 58Combined sources11
Beta strandi63 – 71Combined sources9
Beta strandi74 – 85Combined sources12
Beta strandi91 – 97Combined sources7
Beta strandi98 – 100Combined sources3
Beta strandi102 – 110Combined sources9
Beta strandi112 – 123Combined sources12
Beta strandi127 – 141Combined sources15
Helixi144 – 156Combined sources13
Helixi161 – 163Combined sources3
Beta strandi164 – 166Combined sources3
Beta strandi170 – 173Combined sources4
Helixi175 – 178Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1GKAX-ray3.23A2-181[»]
1S44X-ray1.60A/B2-181[»]
ProteinModelPortaliP58989.
SMRiP58989.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP58989.

Family & Domainsi

Sequence similaritiesi

Belongs to the calycin superfamily. Lipocalin family.Curated

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR003057. Invtbrt_color.
IPR002345. Lipocalin.
IPR022271. Lipocalin_ApoD.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
[Graphical view]
PfamiPF00061. Lipocalin. 1 hit.
[Graphical view]
PIRSFiPIRSF036893. Lipocalin_ApoD. 1 hit.
PRINTSiPR01273. INVTBRTCOLOR.
PR00179. LIPOCALIN.
SUPFAMiSSF50814. SSF50814. 1 hit.

Sequencei

Sequence statusi: Complete.

P58989-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
DKIPNFVVPG KCASVDRNKL WAEQTPNRNS YAGVWYQFAL TNNPYQLIEK
60 70 80 90 100
CVRNEYSFDG KQFVIKSTGI AYDGNLLKRN GKLYPNPFGE PHLSIDYENS
110 120 130 140 150
FAAPLVILET DYSNYACLYS CIDYNFGYHS DFSFIFSRSA NLADQYVKKC
160 170 180
EAAFKNINVD TTRFVKTVQG SSCPYDTQKT V
Length:181
Mass (Da):20,652
Last modified:August 13, 2002 - v1
Checksum:i285EADC1A4F2E353
GO

Cross-referencesi

Web resourcesi

Protein Spotlight

Squeeze me - Issue 26 of September 2002

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1GKAX-ray3.23A2-181[»]
1S44X-ray1.60A/B2-181[»]
ProteinModelPortaliP58989.
SMRiP58989.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-242140.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP58989.

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR003057. Invtbrt_color.
IPR002345. Lipocalin.
IPR022271. Lipocalin_ApoD.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
[Graphical view]
PfamiPF00061. Lipocalin. 1 hit.
[Graphical view]
PIRSFiPIRSF036893. Lipocalin_ApoD. 1 hit.
PRINTSiPR01273. INVTBRTCOLOR.
PR00179. LIPOCALIN.
SUPFAMiSSF50814. SSF50814. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCRA1_HOMGA
AccessioniPrimary (citable) accession number: P58989
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 13, 2002
Last sequence update: August 13, 2002
Last modified: November 2, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Protein Spotlight
    Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.