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P58890

- PDAD2_METMA

UniProt

P58890 - PDAD2_METMA

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Protein

Pyruvoyl-dependent arginine decarboxylase 2

Gene
pdaD2, MM_2595
Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-arginine = agmatine + CO2.UniRule annotation

Cofactori

Pyruvoyl group By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei40 – 412Cleavage (non-hydrolytic) By similarity

GO - Molecular functioni

  1. arginine decarboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Ligandi

Pyruvate

Enzyme and pathway databases

BioCyciMMAZ192952:GCK2-2654-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Pyruvoyl-dependent arginine decarboxylase 2 (EC:4.1.1.19)
Short name:
PvlArgDC 2
Cleaved into the following 2 chains:
Gene namesi
Name:pdaD2
Ordered Locus Names:MM_2595
OrganismiMethanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Taxonomic identifieri192952 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
ProteomesiUP000000595: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 4040Pyruvoyl-dependent arginine decarboxylase 2 subunit beta By similarityPRO_0000023320Add
BLAST
Chaini41 – 183143Pyruvoyl-dependent arginine decarboxylase 2 subunit alpha By similarityPRO_0000023321Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei41 – 411Pyruvic acid (Ser) By similarity

Interactioni

Protein-protein interaction databases

STRINGi192952.MM_2595.

Structurei

3D structure databases

ProteinModelPortaliP58890.

Family & Domainsi

Sequence similaritiesi

Belongs to the PdaD family.

Phylogenomic databases

eggNOGiCOG1945.
HOGENOMiHOG000012204.
KOiK02626.
OMAiYKMSGKI.

Family and domain databases

Gene3Di3.50.20.10. 1 hit.
HAMAPiMF_01404. PvlArgDC.
InterProiIPR016104. Pyr-dep_his/arg-deCO2ase.
IPR016105. Pyr-dep_his/arg-deCO2ase_sand.
IPR002724. Pyruvoyl-dep_arg_deCO2ase.
[Graphical view]
PfamiPF01862. PvlArgDC. 1 hit.
[Graphical view]
PIRSFiPIRSF005216. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
ProDomiPD010449. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF56271. SSF56271. 1 hit.
TIGRFAMsiTIGR00286. TIGR00286. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P58890-1 [UniParc]FASTAAdd to Basket

« Hide

MIPRKAFLTK GTGVHKDRLA SFELALRDAK IEKYNLVSVS SILPPNCKLV    50
PREEGLAELK PGAIVHCVLA RNDTNEPHRL MASAIGTAVP VNEENYGYIS 100
EHHSFGEEEI IAGEYAEDLA ATMLATTLGI EFDAEMAWHE REQVYKASGH 150
IFDTFHMCQT AKGDKDGKWT TTVAAMVFVT SKC 183
Length:183
Mass (Da):20,211
Last modified:July 11, 2002 - v1
Checksum:iEC848E8E644A2360
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008384 Genomic DNA. Translation: AAM32291.1.
RefSeqiNP_634619.1. NC_003901.1.

Genome annotation databases

EnsemblBacteriaiAAM32291; AAM32291; MM_2595.
GeneIDi1480937.
KEGGimma:MM_2595.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008384 Genomic DNA. Translation: AAM32291.1 .
RefSeqi NP_634619.1. NC_003901.1.

3D structure databases

ProteinModelPortali P58890.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 192952.MM_2595.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM32291 ; AAM32291 ; MM_2595 .
GeneIDi 1480937.
KEGGi mma:MM_2595.

Phylogenomic databases

eggNOGi COG1945.
HOGENOMi HOG000012204.
KOi K02626.
OMAi YKMSGKI.

Enzyme and pathway databases

BioCyci MMAZ192952:GCK2-2654-MONOMER.

Family and domain databases

Gene3Di 3.50.20.10. 1 hit.
HAMAPi MF_01404. PvlArgDC.
InterProi IPR016104. Pyr-dep_his/arg-deCO2ase.
IPR016105. Pyr-dep_his/arg-deCO2ase_sand.
IPR002724. Pyruvoyl-dep_arg_deCO2ase.
[Graphical view ]
Pfami PF01862. PvlArgDC. 1 hit.
[Graphical view ]
PIRSFi PIRSF005216. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
ProDomi PD010449. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF56271. SSF56271. 1 hit.
TIGRFAMsi TIGR00286. TIGR00286. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea."
    Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A., Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C., Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S., Bhattacharyya A., Lykidis A., Overbeek R.
    , Klenk H.-P., Gunsalus R.P., Fritz H.-J., Gottschalk G.
    J. Mol. Microbiol. Biotechnol. 4:453-461(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88.

Entry informationi

Entry nameiPDAD2_METMA
AccessioniPrimary (citable) accession number: P58890
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: July 11, 2002
Last modified: May 14, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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