Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P58890

- PDAD2_METMA

UniProt

P58890 - PDAD2_METMA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Pyruvoyl-dependent arginine decarboxylase 2

Gene

pdaD2

Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-arginine = agmatine + CO2.

Cofactori

Pyruvoyl group.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei40 – 412Cleavage (non-hydrolytic)By similarity

GO - Molecular functioni

  1. arginine decarboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Ligandi

Pyruvate

Enzyme and pathway databases

BioCyciMMAZ192952:GCK2-2654-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Pyruvoyl-dependent arginine decarboxylase 2 (EC:4.1.1.19)
Short name:
PvlArgDC 2
Cleaved into the following 2 chains:
Gene namesi
Name:pdaD2
Ordered Locus Names:MM_2595
OrganismiMethanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Taxonomic identifieri192952 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
ProteomesiUP000000595: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 4040Pyruvoyl-dependent arginine decarboxylase 2 subunit betaBy similarityPRO_0000023320Add
BLAST
Chaini41 – 183143Pyruvoyl-dependent arginine decarboxylase 2 subunit alphaBy similarityPRO_0000023321Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei41 – 411Pyruvic acid (Ser)By similarity

Interactioni

Protein-protein interaction databases

STRINGi192952.MM_2595.

Structurei

3D structure databases

ProteinModelPortaliP58890.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PdaD family.Curated

Phylogenomic databases

eggNOGiCOG1945.
HOGENOMiHOG000012204.
KOiK02626.
OMAiYKMSGKI.

Family and domain databases

Gene3Di3.50.20.10. 1 hit.
HAMAPiMF_01404. PvlArgDC.
InterProiIPR016104. Pyr-dep_his/arg-deCO2ase.
IPR016105. Pyr-dep_his/arg-deCO2ase_sand.
IPR002724. Pyruvoyl-dep_arg_deCO2ase.
[Graphical view]
PfamiPF01862. PvlArgDC. 1 hit.
[Graphical view]
PIRSFiPIRSF005216. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
ProDomiPD010449. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF56271. SSF56271. 1 hit.
TIGRFAMsiTIGR00286. TIGR00286. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P58890-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIPRKAFLTK GTGVHKDRLA SFELALRDAK IEKYNLVSVS SILPPNCKLV
60 70 80 90 100
PREEGLAELK PGAIVHCVLA RNDTNEPHRL MASAIGTAVP VNEENYGYIS
110 120 130 140 150
EHHSFGEEEI IAGEYAEDLA ATMLATTLGI EFDAEMAWHE REQVYKASGH
160 170 180
IFDTFHMCQT AKGDKDGKWT TTVAAMVFVT SKC
Length:183
Mass (Da):20,211
Last modified:July 11, 2002 - v1
Checksum:iEC848E8E644A2360
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008384 Genomic DNA. Translation: AAM32291.1.
RefSeqiNP_634619.1. NC_003901.1.
WP_011034508.1. NC_003901.1.

Genome annotation databases

EnsemblBacteriaiAAM32291; AAM32291; MM_2595.
GeneIDi1480937.
KEGGimma:MM_2595.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008384 Genomic DNA. Translation: AAM32291.1 .
RefSeqi NP_634619.1. NC_003901.1.
WP_011034508.1. NC_003901.1.

3D structure databases

ProteinModelPortali P58890.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 192952.MM_2595.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM32291 ; AAM32291 ; MM_2595 .
GeneIDi 1480937.
KEGGi mma:MM_2595.

Phylogenomic databases

eggNOGi COG1945.
HOGENOMi HOG000012204.
KOi K02626.
OMAi YKMSGKI.

Enzyme and pathway databases

BioCyci MMAZ192952:GCK2-2654-MONOMER.

Family and domain databases

Gene3Di 3.50.20.10. 1 hit.
HAMAPi MF_01404. PvlArgDC.
InterProi IPR016104. Pyr-dep_his/arg-deCO2ase.
IPR016105. Pyr-dep_his/arg-deCO2ase_sand.
IPR002724. Pyruvoyl-dep_arg_deCO2ase.
[Graphical view ]
Pfami PF01862. PvlArgDC. 1 hit.
[Graphical view ]
PIRSFi PIRSF005216. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
ProDomi PD010449. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF56271. SSF56271. 1 hit.
TIGRFAMsi TIGR00286. TIGR00286. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea."
    Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A., Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C., Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S., Bhattacharyya A., Lykidis A., Overbeek R.
    , Klenk H.-P., Gunsalus R.P., Fritz H.-J., Gottschalk G.
    J. Mol. Microbiol. Biotechnol. 4:453-461(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88.

Entry informationi

Entry nameiPDAD2_METMA
AccessioniPrimary (citable) accession number: P58890
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: July 11, 2002
Last modified: October 29, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3