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P58889

- PDAD1_METMA

UniProt

P58889 - PDAD1_METMA

Protein

Pyruvoyl-dependent arginine decarboxylase 1

Gene

pdaD1

Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (11 Jul 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-arginine = agmatine + CO2.

    Cofactori

    Pyruvoyl group.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei44 – 452Cleavage (non-hydrolytic)By similarity

    GO - Molecular functioni

    1. arginine decarboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. arginine catabolic process Source: InterPro

    Keywords - Molecular functioni

    Decarboxylase, Lyase

    Keywords - Ligandi

    Pyruvate

    Enzyme and pathway databases

    BioCyciMMAZ192952:GCK2-300-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Pyruvoyl-dependent arginine decarboxylase 1 (EC:4.1.1.19)
    Short name:
    PvlArgDC 1
    Cleaved into the following 2 chains:
    Gene namesi
    Name:pdaD1
    Ordered Locus Names:MM_0286
    OrganismiMethanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
    Taxonomic identifieri192952 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
    ProteomesiUP000000595: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 4444Pyruvoyl-dependent arginine decarboxylase 1 subunit betaBy similarityPRO_0000023318Add
    BLAST
    Chaini45 – 165121Pyruvoyl-dependent arginine decarboxylase 1 subunit alphaBy similarityPRO_0000023319Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei45 – 451Pyruvic acid (Ser)By similarity

    Interactioni

    Protein-protein interaction databases

    STRINGi192952.MM_0286.

    Structurei

    3D structure databases

    ProteinModelPortaliP58889.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PdaD family.Curated

    Phylogenomic databases

    eggNOGiCOG1945.
    HOGENOMiHOG000012204.
    KOiK02626.
    OMAiGYISEYH.

    Family and domain databases

    Gene3Di3.50.20.10. 1 hit.
    HAMAPiMF_01404. PvlArgDC.
    InterProiIPR016104. Pyr-dep_his/arg-deCO2ase.
    IPR016105. Pyr-dep_his/arg-deCO2ase_sand.
    IPR002724. Pyruvoyl-dep_arg_deCO2ase.
    [Graphical view]
    PfamiPF01862. PvlArgDC. 1 hit.
    [Graphical view]
    PIRSFiPIRSF005216. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
    ProDomiPD010449. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF56271. SSF56271. 1 hit.
    TIGRFAMsiTIGR00286. TIGR00286. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P58889-1 [UniParc]FASTAAdd to Basket

    « Hide

    MITKLIPKKV FFTSGAGTHP EKLESFEAAL RDACIEKFNL VTVSSILPPR    50
    CEIVTKEEGL KELSPGEIVF CVMSRISSND PGKTLTSSVG CALPVDISKH 100
    GYISEYHAYE ESAQDAGAHA VKLAESMYST WTKEEPLKTF SIPRSSTVKD 150
    SGDWMTVISA AVFVI 165
    Length:165
    Mass (Da):17,992
    Last modified:July 11, 2002 - v1
    Checksum:i5F56185DBD942D92
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008384 Genomic DNA. Translation: AAM29982.1.
    RefSeqiNP_632310.1. NC_003901.1.
    WP_011032240.1. NC_003901.1.

    Genome annotation databases

    EnsemblBacteriaiAAM29982; AAM29982; MM_0286.
    GeneIDi1478628.
    KEGGimma:MM_0286.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008384 Genomic DNA. Translation: AAM29982.1 .
    RefSeqi NP_632310.1. NC_003901.1.
    WP_011032240.1. NC_003901.1.

    3D structure databases

    ProteinModelPortali P58889.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 192952.MM_0286.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM29982 ; AAM29982 ; MM_0286 .
    GeneIDi 1478628.
    KEGGi mma:MM_0286.

    Phylogenomic databases

    eggNOGi COG1945.
    HOGENOMi HOG000012204.
    KOi K02626.
    OMAi GYISEYH.

    Enzyme and pathway databases

    BioCyci MMAZ192952:GCK2-300-MONOMER.

    Family and domain databases

    Gene3Di 3.50.20.10. 1 hit.
    HAMAPi MF_01404. PvlArgDC.
    InterProi IPR016104. Pyr-dep_his/arg-deCO2ase.
    IPR016105. Pyr-dep_his/arg-deCO2ase_sand.
    IPR002724. Pyruvoyl-dep_arg_deCO2ase.
    [Graphical view ]
    Pfami PF01862. PvlArgDC. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF005216. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
    ProDomi PD010449. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF56271. SSF56271. 1 hit.
    TIGRFAMsi TIGR00286. TIGR00286. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea."
      Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A., Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C., Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S., Bhattacharyya A., Lykidis A., Overbeek R.
      , Klenk H.-P., Gunsalus R.P., Fritz H.-J., Gottschalk G.
      J. Mol. Microbiol. Biotechnol. 4:453-461(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88.

    Entry informationi

    Entry nameiPDAD1_METMA
    AccessioniPrimary (citable) accession number: P58889
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 11, 2002
    Last sequence update: July 11, 2002
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3