Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P58883

- PYRF_CALS4

UniProt

P58883 - PYRF_CALS4

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Orotidine 5'-phosphate decarboxylase

Gene

pyrF

Organism
Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Orotidine 5'-phosphate = UMP + CO2.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei106 – 1061Proton donorBy similarity

GO - Molecular functioni

  1. orotidine-5'-phosphate decarboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
  2. 'de novo' UMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Biological processi

Pyrimidine biosynthesis

Enzyme and pathway databases

BioCyciCSUB273068:GJEB-2765-MONOMER.
UniPathwayiUPA00070; UER00120.

Names & Taxonomyi

Protein namesi
Recommended name:
Orotidine 5'-phosphate decarboxylase (EC:4.1.1.23)
Alternative name(s):
OMP decarboxylase
Short name:
OMPDCase
Short name:
OMPdecase
Gene namesi
Name:pyrF
Ordered Locus Names:TTE1532
OrganismiCaldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis)
Taxonomic identifieri273068 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacteraceaeCaldanaerobacter
ProteomesiUP000000555: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 307307Orotidine 5'-phosphate decarboxylasePRO_0000134636Add
BLAST

Proteomic databases

PRIDEiP58883.

Interactioni

Protein-protein interaction databases

STRINGi273068.TTE1532.

Structurei

3D structure databases

ProteinModelPortaliP58883.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0284.
HOGENOMiHOG000245747.
KOiK01591.
OMAiHIHARHP.
OrthoDBiEOG6DZF33.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_01215. OMPdecase_type2.
InterProiIPR013785. Aldolase_TIM.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTiSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.
TIGRFAMsiTIGR02127. pyrF_sub2. 1 hit.

Sequencei

Sequence statusi: Complete.

P58883-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFVDRLIESV KAKKTPVVVG LDPRIEMIPD FIKEEAFRRK GNGVEGIAEA
60 70 80 90 100
MYLFNKGIID AVYDLIPAVK IQVAFYEAYG IEGFKAFFRT AEYAKSLGLI
110 120 130 140 150
VIADVKRGDI QDVAKMYSKA YLQNPLFDAI TVNPYMGEDS MVPYLEDVEK
160 170 180 190 200
FGKGIFVLVK TSNRSSKDVQ DIETKKGGYV YQEVAKMISR LSKVIVGKYG
210 220 230 240 250
YSSIGAVVGA TYPFEAKILR EEMPRCYFLV PGYGAQGATA EDVVNCFDEE
260 270 280 290 300
GYGAIINSSR GVIYAYRSDF WKEAYSEYEY GQAAREEVIL MTGMINNALV

KRKYIAS
Length:307
Mass (Da):34,399
Last modified:June 24, 2002 - v1
Checksum:iF1D89D49BDFEFE01
GO

Sequence cautioni

The sequence AAM24743.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008691 Genomic DNA. Translation: AAM24743.1. Different initiation.
RefSeqiNP_623139.1. NC_003869.1.

Genome annotation databases

EnsemblBacteriaiAAM24743; AAM24743; TTE1532.
GeneIDi996047.
KEGGitte:TTE1532.
PATRICi23897768. VBITheTen82880_1534.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008691 Genomic DNA. Translation: AAM24743.1 . Different initiation.
RefSeqi NP_623139.1. NC_003869.1.

3D structure databases

ProteinModelPortali P58883.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273068.TTE1532.

Proteomic databases

PRIDEi P58883.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM24743 ; AAM24743 ; TTE1532 .
GeneIDi 996047.
KEGGi tte:TTE1532.
PATRICi 23897768. VBITheTen82880_1534.

Phylogenomic databases

eggNOGi COG0284.
HOGENOMi HOG000245747.
KOi K01591.
OMAi HIHARHP.
OrthoDBi EOG6DZF33.

Enzyme and pathway databases

UniPathwayi UPA00070 ; UER00120 .
BioCyci CSUB273068:GJEB-2765-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_01215. OMPdecase_type2.
InterProi IPR013785. Aldolase_TIM.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00215. OMPdecase. 1 hit.
[Graphical view ]
SMARTi SM00934. OMPdecase. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
TIGRFAMsi TIGR02127. pyrF_sub2. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 15242 / JCM 11007 / NBRC 100824 / MB4.

Entry informationi

Entry nameiPYRF_CALS4
AccessioniPrimary (citable) accession number: P58883
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 24, 2002
Last sequence update: June 24, 2002
Last modified: October 29, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3