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Reviewed, UniProtKB/Swiss-Prot P58766 (PLDZ1_ARATH)

Last modified November 3, 2009. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Phospholipase D zeta
      Short name=AtPLDzeta
      Short name=PLD zeta
    EC=3.1.4.4
Gene names
Name: PLDZETA
Ordered Locus Names: At5g25370
ORF Names: F18G18.110
OrganismArabidopsis thaliana (Mouse-ear cress) [Complete proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

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Protein attributes

Sequence length820 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Function

Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond.

Catalytic activity

A phosphatidylcholine + H2O = choline + a phosphatidate.

Cofactor

Calcium By similarity.

Subcellular location

Cytoplasm By similarity. Membrane; Peripheral membrane protein By similarity.

Domain

C2 domain is a calcium-binding fold, and the binding promotes the protein association with membranes. A lower affinity toward calcium can be anticipated for PLD alpha due to the absence of two potential calcium ligands.

Sequence similarities

Belongs to the phospholipase D family. C2-PLD subfamily.

Contains 1 C2 domain.

Contains 2 PLD phosphodiesterase domains.

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 820820Phospholipase D zeta
PRO_0000218817

Regions

Domain1 – 117117C2
Domain334 – 37138PLD phosphodiesterase 1
Domain662 – 68928PLD phosphodiesterase 2

Sites

Active site3391 Potential
Active site3411 Potential
Active site3461 Potential
Active site6671 Potential
Active site6691 Potential
Active site6741 Potential

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Sequences

Sequence LengthMass (Da)Tools
P58766-1 [UniParc].

Last modified April 3, 2002. Version 1.
Checksum: FFB9247276BCEB7B

FASTA82093,362
        10         20         30         40         50         60 
MTEQLLLHGT LEVKIYRIDK LHQRSRFNLC GKGNKEPTGK KTQSQIKRLT DSCTSLFGGH 

        70         80         90        100        110        120 
LYATIDLDRS RVARTMMRRH PKWLQSFHVY TAHSISKIIF TVKEDEPVSA SLIGRAYLPV 

       130        140        150        160        170        180 
TEVITGQPID RWLDILDENR RPIQGGSKLH VRVKFTHVTQ DVNWNKGIIL PSFNGVPNAY 

       190        200        210        220        230        240 
FNQREGCKVT LYQDAHVLNE YPDVTLTGGQ VIYKHHRCWE EIFDAIWEAK HLIYIAGWSV 

       250        260        270        280        290        300 
NTDVTLVRDP KRTRPGGDLK LGELLKKKAE ENVTVLMLVW DDRTSHEVFK RDGLMMTHDQ 

       310        320        330        340        350        360 
ETYDYFKNTK VRCVLCPRNP DNGDSIVQGF EVATMFTHHQ KTIVVDSEVD GSLTKRRIVS 

       370        380        390        400        410        420 
FLGGIDLCDG RYDTVEHPLF GTLNSVHAND FHQPNFDGAS IKKGGPREPW HDIHCKLDGP 

       430        440        450        460        470        480 
AAWDVLYNFE QRWMKQGSGR RYLISMAQLA EITVPPLPIV QPDNEEGWTV QVFRSIDDGA 

       490        500        510        520        530        540 
VEGFPEDPRE AASIGLISGK DNVIERSIQD AYVNAIRRAK NFIYIENQYF LGSSFGWNSR 

       550        560        570        580        590        600 
DINLNEINAL QLIPKEISLK IVSKIEAGER FSVYIVIPLW PEGKPGSASV QAILDWQRRT 

       610        620        630        640        650        660 
MEMMYTDIII ALRKKGLDAN PRDYLTFFCL GNREKGKVGE YLPPEKPEAN SDYARAQESR 

       670        680        690        700        710        720 
RFMIYVHSKM MIVDDEYIII GSANINQRSM DGGRDTEIAM GAYQPSHLLS TNNMRPVGQI 

       730        740        750        760        770        780 
FSFRISLWLE HLRVTTNAFQ CPESEECIRM VNATADELWG LYSAQEYPRN DDLPGHLLSY 

       790        800        810        820 
PISIGSNGEV TNLAGTEFFP DTNAKVVGEK SNYLPPILTS

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References

[1]"Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana."
Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K. expand/collapse author list , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.
Nature 408:823-826(2000) [PubMed: 11130714] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
+Additional computationally mapped references.

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Cross-references

Sequence databases

AC006258 Genomic DNA. No translation available.
IPIIPI00524711.
RefSeqNP_197919.1.
UniGeneAt.54992

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGP58766.

Genome annotation databases

GeneID832609.
GenomeReviewsGene locus AT5G25370 in contig BA000015_GR.
KEGGath:AT5G25370.
NMPDRfig|3702.1.peg.24735.

Organism-specific databases

TAIRAt5g25370.

Phylogenomic databases

OMAFRSIDDG.

Enzyme and pathway databases

BRENDA3.1.4.4. 302.

Gene expression databases

ArrayExpressP58766.
GenevestigatorP58766.
GermOnlineAT5G25370. Arabidopsis thaliana.

Family and domain databases

InterProIPR000008. C2_Ca-dep.
IPR015679. Phospholipase_D.
IPR011402. PLD_pln.
IPR001736. PLipase_D/transphosphatidylase.
IPR004019. YLP_motif.
[Graphical view]
PANTHERPTHR18896. Phospholipase_D. 1 hit.
PfamPF00614. PLDc. 2 hits.
PF02757. YLP. 2 hits.
[Graphical view]
PIRSFPIRSF036470. PLD_plant. 1 hit.
SMARTSM00239. C2. 1 hit.
SM00155. PLDc. 2 hits.
[Graphical view]
PROSITEPS50004. C2. False negative.
PS50035. PLD. 2 hits.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry namePLDZ1_ARATH
AccessionPrimary (citable) accession number: P58766
Entry history
Integrated into UniProtKB/Swiss-Prot: April 3, 2002
Last sequence update: April 3, 2002
Last modified: November 3, 2009
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

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Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents