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P58741 (UPPP2_AGRT5) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase 2

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein 2
Undecaprenyl pyrophosphate phosphatase 2
Gene names
Name:uppP2
Synonyms:bacA2, upk2
Ordered Locus Names:Atu0998
ORF Names:AGR_C_1833
OrganismAgrobacterium tumefaciens (strain C58 / ATCC 33970) [Reference proteome] [HAMAP]
Taxonomic identifier176299 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacteriumAgrobacterium tumefaciens complex

Protein attributes

Sequence length278 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 278278Undecaprenyl-diphosphatase 2 HAMAP-Rule MF_01006
PRO_0000151080

Regions

Transmembrane43 – 6321Helical; Potential
Transmembrane88 – 10821Helical; Potential
Transmembrane119 – 13921Helical; Potential
Transmembrane149 – 16921Helical; Potential
Transmembrane194 – 21421Helical; Potential
Transmembrane226 – 24621Helical; Potential
Transmembrane254 – 27421Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P58741 [UniParc].

Last modified March 5, 2002. Version 1.
Checksum: 819EF0CD1FCF13B8

FASTA27830,075
        10         20         30         40         50         60 
MSMGWMEAGF LGLLQGLTEF LPVSSSAHLR IAGEFLPSGA DPGAAFTAIT QIGTEMAVLV 

        70         80         90        100        110        120 
YFWSDIMRIA AAWLRQNLRL GEYNKADARL GWLIIVGSVP IVFLGLFFKD AIEHSLRNLY 

       130        140        150        160        170        180 
ITAVMLIVFG IVLGLADRIG EKRYKLNQLI WRDGILFGFA QAMALIPGVS RSGGTISAGL 

       190        200        210        220        230        240 
LLGYTREAAA RYSFLLAVPA VFGSGFYQLF KSIGEDNPVG WGQTGLATLI AFIVGYAVIV 

       250        260        270 
VFLKLVSTKS YMPFVWYRVV IGFILLALLG TGVISAGG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE007869 Genomic DNA. Translation: AAK86807.1.
PIRAF2699.
F97481.
RefSeqNP_354022.1. NC_003062.2.

3D structure databases

ProteinModelPortalP58741.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING176299.Atu0998.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK86807; AAK86807; Atu0998.
GeneID1133036.
KEGGatu:Atu0998.
PATRIC20811741. VBIAgrTum91616_1012.

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMASDIMRIA.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycAGRO:ATU0998-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP2_AGRT5
AccessionPrimary (citable) accession number: P58741
Entry history
Integrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: March 5, 2002
Last modified: May 14, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families