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P58740 (UPPP1_AGRT5) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase 1

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein 1
Undecaprenyl pyrophosphate phosphatase 1
Gene names
Name:uppP1
Synonyms:bacA1, upk1
Ordered Locus Names:Atu0294
ORF Names:AGR_C_505
OrganismAgrobacterium tumefaciens (strain C58 / ATCC 33970) [Reference proteome] [HAMAP]
Taxonomic identifier176299 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacteriumAgrobacterium tumefaciens complex

Protein attributes

Sequence length268 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 268268Undecaprenyl-diphosphatase 1 HAMAP-Rule MF_01006
PRO_0000151079

Regions

Transmembrane5 – 2521Helical; Potential
Transmembrane43 – 6321Helical; Potential
Transmembrane84 – 10421Helical; Potential
Transmembrane107 – 12721Helical; Potential
Transmembrane184 – 20421Helical; Potential
Transmembrane218 – 23821Helical; Potential
Transmembrane247 – 26721Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P58740 [UniParc].

Last modified March 5, 2002. Version 1.
Checksum: BFE3B436475ECA97

FASTA26828,615
        10         20         30         40         50         60 
MGDQSIISAL LLGIIEGLTE FIPVSSTAHV LLAGHFLGFK SPGNTFAVLI QLGAILAILL 

        70         80         90        100        110        120 
VYFQKLVSIA VAMPTSAKAR RFVLAVLVAF LPAAVIGALA HDFIKTVLFE TPMLICVVLI 

       130        140        150        160        170        180 
IGGFILLAVD RMPLKPKYTD IMDYPPSLAF KIGLFQCLAM IPGTSRSGAT IVGALLMGTD 

       190        200        210        220        230        240 
KRSAAEFSFF LAMPTMLGAF VLDLYKNRDA LSFDDSALIA VGFVAAFVSG LFVVRSLLDF 

       250        260 
VSRRGFAPFA WWRIVIGALG LVALLVIG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE007869 Genomic DNA. Translation: AAK86109.1.
PIRAF2612.
D97394.
RefSeqNP_353324.1. NC_003062.2.

3D structure databases

ProteinModelPortalP58740.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING176299.Atu0294.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK86109; AAK86109; Atu0294.
GeneID1132332.
KEGGatu:Atu0294.
PATRIC20810271. VBIAgrTum91616_0285.

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMAFAWWRIV.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycAGRO:ATU0294-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP1_AGRT5
AccessionPrimary (citable) accession number: P58740
Entry history
Integrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: March 5, 2002
Last modified: May 14, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families